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Summary Expression Gene Literature (11) GO Terms (20) Nucleotides (82) Proteins (29) Interactants (244) Wiki
XB-GENEPAGE-5959107
Gene Symbol: lgr4

Gene Name: leucine-rich repeat containing G protein-coupled receptor 4

Synonyms: ( Add synonyms , Nomenclature history )

Gene Function: glycoprotein hormone receptor

Protein Function :
Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and is involved in the formation of various organs. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates wi...[+]

Interactants: Loading ...
OMIM Diseases: BONE MINERAL DENSITY QUANTITATIVE TRAIT LOCUS 17; BMND17

 
Xenbase Gene ID XB-GENE-5959108 XB-GENE-17346282 XB-GENE-5959148
Gene Symbol lgr4 lgr4.L lgr4.S
Chromosome Chr04 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA RefSeq NCBI Nucleotide RefSeq
Protein RefSeq Swiss-Prot NCBI Protein TrEMBL RefSeq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine lgr4 lgr4.L lgr4.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards LGR4 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Lgr4 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
lgr4 ZFIN Ensembl
chicken
GEISHA LGR4 Ensembl
fruit fly
FLYBASE Lgr4 Ensembl
worm
WORMBASE
Publications
First Spatio-temporal expression profile of stem cell-associated gene LGR5 in the intestine during thyroid hormone-dependent metamorphosis in Xenopus laevis., PLoS One 2010                      
Most Recent RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6., Nature 2018    
All View All Papers 2 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 17 terms 3 terms 11 terms
PANTHER lgr4
KEGG Pathways K04309 K04309 K04309
KOG [T] Glycoprotein hormone receptor
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
Morpholino lgr4 MO1 , lgr4 MO2 , lgr4 MO3 lgr4 MO1 , lgr4 MO2 , lgr4 MO3 lgr4 MO1 , lgr4 MO2 , lgr4 MO3
Affymetrix 1.0 Str.14297.1.A1_at [+]
Affymetrix 2.0 Xl2.54861.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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