Gene Symbol: nodal3.1 [provisional] Gene Name: nodal homolog 3, gene 1 [provisional] Synonyms: Xnr3, nr3, Xnr-3 Add Xenopus synonyms Gene Function: transforming growth factor beta and bone morphogenetic protein related protein Interactants: sia1(58) , chrd(37) , nodal(34) , gsc(32) , wnt8a(31) , t(29) , nodal1(22) View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_203533|Xenopus (Silurana) tropicalis nodal homolog (nodal), mRNA GGCACGAGGCAAGAAGCATCTCCTCAGCTGGAAGATATCAGGAGTCACCAAGAATCTACCCAGAGATGGCCTTTCTCAGCCTCTTCTTGTGCCTTGTGTTTAGCTCCCCACTGATGGCGATGCCTCCAGCCCTACAGGGGAGAAAGGCCATCAGTCCAGCTTCTATCCTAAAGGGCCCATCCACAGATAATGGAGCCAGAGACTTTCATGGAAGGAAGTTCCCCCATTTCATGATGCAGCTGTACCAGAATATCATCAGCAGAAGAGATAAAGATCTCTCCAACCTGGAACATCCAACTCTTCAGGAATCTGATACCGTCCAAAGCTTCATTGCTAAAAGTTACACTACAGTGGGAAATCACTGGACCTTGTTCTTTGACATGTCCTCCATCTCCACAAACAATGAGCTGAAGTTGGCTGAGCTACGTATTTGCCTCCCTTCCTTTGGGAAGTCCCACAGTGTGACAGTAGAGATCTACCATACCAAGGACACAAAGGAGAAATTATTCATGGGATCATTCAAGACCAAGATTTCTTCTGCACTAGATGCTGACTGCAAGGTCTTCAACCTCACCATGGTGCTGCACAACTATCTGATCAGGGGAAAGAGATTAATTAAGGATGAATACATACAGGCAAAGGGTCTCCTTCTGAGAGATCTAGAGAAGAGTGCTGCAGAGAAAGGAGCAGAAAATGTAGATACATTGAAACAAGATAAACATCATGTATCCGACTTTGCTGCAGAGAGAATCATACTGGTTGTGTTTGCTAAAGAAAGATCTCAAGCTAAACCTGATCCCCCCAGCCTTGGCAAGCAGCTGTTCCCTTTAAAGTATGGTATGGCTGATAATGCCAACAAGGTGAATGGATTCAGGAGACTTAGGAGGAACAAGAAAGAGAAAACAAGAATGGATGTGGGTACCACTCCCCCCAAACCTGTTGAAGAAATCAAACCCAAGTGCAGGAAGGTGGACATGTTTGTGGACTTTCAGAAGATCGGATGGGGCAGCTGGATTGTGTATCCCAAGGCATATAATGCATACAGATGTGAATCAGCCTGTGCAGTTCCACTGAATGAGACGGACGATGCAACAAACTATTCCTACATTAAGAGTTTGCTCCCTCTGAGCGACACGGAGAGAAGAGAATGCCCTTCCTGTGTCCCCGTGAAGATGAGGTCCATGTCAATGTTGTACTATGAGAATGAAGAGTTTATCCTGCGGCACCATGAAGAGATGATTGTAGAAGAATGTGGGTTCAAGGACATTTAACAGACTTTGTCTCTCAGACTTTTCTTTCCACATCCCACCAACTAAATTCTTATTAGATTCCTTATTTATGCCATGTTGTTTCTCTTTTAGACATATATTTATCTTTTTTATTTTGATTTTTGATCTGTTCTACTGAGAAGCTGATCTATGGATCCACTTTATACAGAGTCGCACTTCTTATTCCACTATTTATTGTTCACACGATATTGACTCCGTTAGCCCTGCTCTGTATTCAGTTTAAAATGTAATTGTAATTTTTTTAATTTAATGAACTTAGAAATATAGGCAATGTTGATTTACTATTTGCACATATTAATTCTGAAAATTGTGATACAGTTAAAATAAAAAAATGTTTAGTGAAAAAAAAAAAAAAAAAA	Refseq >NM_001085790|Xenopus laevis nodal homolog 3, gene 1 (nodal3.1), mRNA GTCTGAACAAGAAGCATCTCCTCAGTTGGAAGATATCTGGAGTCACCACAAATCTACCCAGAGATGGCATTTCTGAACCTGTTCTTCTGCCTTGTGTTTATCTCCCCACTGATGGCGATGCCTCCAGTCCTACAGGGGAGAAAGTCCATCAGTCCAGATTCTATCCTAAAGGACACATCCACAGATATTGGAGCCAGAGAATTTCAAGGAAGGAAGTTCCCCAATTTTATGATGCAGCTGTACCAGAATATCATCAGAGGTAGAGATAATGATCTATCCAACCTGGAACATCCTACTCTTCAGGAATCTGATACCGTCCAAAGCTTCATCGCTAAAAGTTATACTACAGTGGGGAATCGCTGGACCTTGTTCTTTGATATGTCCTCCATCTCTAGAAGCAACGAGCTGAAGTTGGCTGAGCTACGTATTTGCCTCCCTTCTTTTAGAAAGTCTCACAGTGTGACAGTAGACATCTACCATACCAATGACGGCAAGGAGAAATTATTCATGGGATCATTTAAGACCAAGCTTTCTTCTGCACTAGATTCTGACTGCAAGGTCTTCAATCTCACCATCTTGTTGCAGAACTTTCTGACCAGGGGAAAGAGGTTAATAAAGGATGAATACATACAGGCAAAAGGTCTCCATCTGAAAGATCTAGAGAAGAGTGCTACAGAAAAAGATACAGAAAATGTAGATACGATGAAGCAACATCAATATCACGTATCTGACTTTGCTGCAGAAAGAATAATGCTGGTTGTGTTTGCTAAAGAACAGTCTCATGCTAAACCTGATCCCCCCAGTCTTGGCCAGAAGCTGTTCCCTTCAAAGTATGGTATTGATGATAATGCCAACAAGGTGAATGGATTTCGGAGACTTAGAAGGAACAAGAAAGAGAAAACACAAATCCATGTGAGCACCGTTCCACCTAAACCTATTGAAGAGATCAAACCCGAGTGCAAGAAGGTGGACATGTTTGTGGACTTTCAGAAGATCGGATGGGGCAGCTGGATTATTTATCCCAAGGCATATAATGCATATAGATGTGAATCCACTTGTGCAGTTCCACAGAATGAGACAGAGAATGCAACAAACCATTCCTACATTAAGAGTTTGCTCCCTCTGAGTGACATGGAGAGAAAAGAGTGTCCCTCCTGTGTCCCCATGAAGATGATGTCCATGTCAATGTTGTACTATGAGAATGAAGATTTTATCCTGAGGCACCATGAAGAGATGATTGTAGAAGAATGTGGATTCAAGGACATGTAACACAGACTGTCTCCTAAACTTTTTTTACTACATCCAACTAACTACATCGTTTCTTGGATTCCTTATTTATGCCATGTTTTTAACATTACTGTTTTAGGCACATATTTATCTTTTGTTTTTTAGATTTGATTTTTAATCTGTTGTGCCGATCCATGGATCCACATTTTACAGAGCAGCACTTCTTGTCCCACTATTTATTGTGCACATGAGATTGGCTCTGTTTTCCAGTTAAAGCTATATTTTGTGCAATGTTTTATATTTTTTATGAAAAAGGGCAACATTGATATACAATGTAGATATTAATTCTAACATGGAATATCGTGATAGATTTGAATAAAAATGTTCAGCTAAAAAAAAAAAAAAAA
Protein		Refseq >NP_988864|nodal homolog 3-A precursor [Xenopus (Silurana) tropicalis] MAFLSLFLCLVFSSPLMAMPPALQGRKAISPASILKGPSTDNGARDFHGRKFPHFMMQLYQNIISRRDKDLSNLEHPTLQESDTVQSFIAKSYTTVGNHWTLFFDMSSISTNNELKLAELRICLPSFGKSHSVTVEIYHTKDTKEKLFMGSFKTKISSALDADCKVFNLTMVLHNYLIRGKRLIKDEYIQAKGLLLRDLEKSAAEKGAENVDTLKQDKHHVSDFAAERIILVVFAKERSQAKPDPPSLGKQLFPLKYGMADNANKVNGFRRLRRNKKEKTRMDVGTTPPKPVEEIKPKCRKVDMFVDFQKIGWGSWIVYPKAYNAYRCESACAVPLNETDDATNYSYIKSLLPLSDTERRECPSCVPVKMRSMSMLYYENEEFILRHHEEMIVEECGFKDI UniProtKB UniProtKB	Refseq >NP_001079259|nodal homolog 3-A precursor [Xenopus laevis] MAFLNLFFCLVFISPLMAMPPVLQGRKSISPDSILKDTSTDIGAREFQGRKFPNFMMQLYQNIIRGRDNDLSNLEHPTLQESDTVQSFIAKSYTTVGNRWTLFFDMSSISRSNELKLAELRICLPSFRKSHSVTVDIYHTNDGKEKLFMGSFKTKLSSALDSDCKVFNLTILLQNFLTRGKRLIKDEYIQAKGLHLKDLEKSATEKDTENVDTMKQHQYHVSDFAAERIMLVVFAKEQSHAKPDPPSLGQKLFPSKYGIDDNANKVNGFRRLRRNKKEKTQIHVSTVPPKPIEEIKPECKKVDMFVDFQKIGWGSWIIYPKAYNAYRCESTCAVPQNETENATNHSYIKSLLPLSDMERKECPSCVPMKMMSMSMLYYENEDFILRHHEEMIVEECGFKDM UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.7735	Xl.989
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		23 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human
mouse
zebrafish

Publications
First:		A nodal-related gene defines a physical and functional domain within the Spemann organizer. [Cell 1995]
Most recent:		The dual regulator Sufu integrates Hedgehog and Wnt signals in the early Xenopus embryo. [Dev Biol 2013]
		View All Papers 22 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		growth factor activity
Biological:
Cellular Component:
EC:
KOG:		[T] Transforming growth factor beta, bone morphogenetic protein and related proteins

Reagents		tropicalis	laevis
Clones		EXRC - 1 clone(s)	EXRC - 1 clone(s)
		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0			Xl.989.1.S1_s_at [+] Xl.989.1.S1_at
Affymetrix 2.0			Xl2.989.1.S1_s_at [+] Xl2.989.1.S1_at

Symbol legend[+]

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