Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (125) GO Terms (34) Nucleotides (92) Proteins (39) Interactants (708) Wiki
XB-GENEPAGE-5966550
Gene Symbol:
thra

Gene Name:
thyroid hormone receptor alpha

Synonyms:
erba , c-erba , TRalpha ( Add synonyms , Nomenclature history )

Gene Function:


Protein Function :
High affinity receptor for triiodothyronine (T3).



Interactants:
Loading ...

Diseases: 


Disease Ontology:
congenital nongoitrous hypothryoidism 6

OMIM:
HYPOTHYROIDISM, CONGENITAL, NONGOITROUS, 6; CHNG6

External Links:
 
Xenbase Gene ID XB-GENE-5966551 XB-GENE-5966552 XB-GENE-17340389
Gene Symbol thra thra.L thra.S
Chromosome Chr10 chr9_10L chr9_10S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 734136
397942
108702484
mRNA RefSeq RefSeq NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. NCBI Protein NCBI Protein  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine thra thra.L thra.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards THRA OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Thra MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Thra Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR thraa thrab ZFIN Ensembl
chicken
GEISHA THRA Ensembl
fruit fly
worm
Publications
First Thyroid hormones are corequisites for estradiol-17beta in vitro induction of Xenopus vitellogenin synthesis and secretion., Dev Biol 1982  
Most Recent Evaluation of a multiplexed, multispecies nuclear receptor assay for chemical hazard assessment., Toxicol In Vitro 2020  
All View All Papers 1 paper(s) referencing OMIMs 4 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 28 terms 15 terms 11 terms
PANTHER thra
KEGG Pathways K05547 K05547 K05547
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks thra
Antibodies Thra-Thrb Ab1 , Thra Ab1 Thra-Thrb Ab1 , Thra Ab1 Thra Ab1 , Thra-Thrb Ab1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.15.0
Major funding for Xenbase is provided by grant P41 HD064556