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Summary Expression Gene Literature (129) GO Terms (10) Nucleotides (142) Proteins (26) Interactants (608) Wiki
XB-GENEPAGE-5995151
Gene Symbol:
smad4.2

Gene Name:
SMAD family member 4, gene 2

Synonyms:
xsmad4 , jip , dpc4 , madh4 , smad10 , XSmad4b , XSmad4beta , Smad4b , Smad4beta , smad4.2-a , smad4.2-b ( Add synonyms , Nomenclature history )

Gene Function:
TGFbeta receptor signaling protein SMAD and related proteins

Protein Function :



Interactants:
Loading ...

Diseases: 


Disease Ontology:
juvenile polyposis syndrome [+]

OMIM:
PANCREATIC CANCER [+]

External Links:
 
Xenbase Gene ID XB-GENE-5995152 XB-GENE-6256010 XB-GENE-5995204
Gene Symbol smad4.2 smad4.2.L smad4.2.S
Chromosome scaffold_6425 chr8L chr8S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100188925
403356
108700426
mRNA NCBI Nucleotide RefSeq NCBI Nucleotide
Protein NCBI Protein RefSeq NCBI Protein
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine smad4.2 smad4.2.L smad4.2.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tegg032k01      
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SMAD4 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Smad4 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Smad4 Ensembl
zebrafish
ZFIN, AGR smad4a ZFIN Ensembl
chicken
GEISHA SMAD4 Ensembl
fruit fly
worm
Publications
First A human Mad protein acting as a BMP-regulated transcriptional activator., Nature 1996  
Most Recent Wip1 regulates Smad4 phosphorylation and inhibits TGF-β signaling., EMBO Rep 2020  
All View All Papers 19 paper(s) referencing morpholinos 3 paper(s) referencing OMIMs 6 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 8 terms 7 terms 7 terms
PANTHER smad4.2
KEGG Pathways K04501 K04501
KOG [TK] TGFbeta receptor signaling protein SMAD and related proteins
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks smad4.2
Antibodies Smad4 Ab1 Smad4 Ab1 Smad4 Ab1
Morpholinos smad4.2 MO1 , smad4.2 MO2 , smad4.2 MO3 smad4.2 MO1 , smad4.2 MO2 , smad4.2 MO3 smad4.2 MO1 , smad4.2 MO2 , smad4.2 MO3
ORFs smad4.2.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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