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XB-GENEPAGE-5995151
Gene Symbol:
smad4.2
Gene Name: SMAD family member 4, gene 2
Synonyms:
xsmad4
,
jip
,
dpc4
,
madh4
,
smad10
,
XSmad4b
,
XSmad4beta
,
Smad4b
,
Smad4beta
,
smad4.2-a
,
smad4.2-b
( Gene Function: TGFbeta receptor signaling protein SMAD and related proteins Protein Function
![]() Interactants:
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Diseases: Disease Ontology:
juvenile polyposis syndrome
OMIM:
PANCREATIC CANCER
External Links:
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Xenbase Gene ID | XB-GENE-5995152 | XB-GENE-6256010 | XB-GENE-5995204 | |||||
Gene Symbol | smad4.2 | smad4.2.L | smad4.2.S | Chromosome | Chr8 | chr8L | chr8S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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Version 9.1
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
100188925
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403356
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108700426
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mRNA |
NCBI Nucleotide
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser) |
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Proteomics | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Embryonic Protein Expression | Stage profile:![]() |
Stage profile:![]() |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | smad4.2 | smad4.2.L | smad4.2.S | |||||
Phenotype | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Smith Morpholino Screen | tegg032k01 | |||||||
Orthology |
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human |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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worm |
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Publications | ||||||||
First |
A human Mad protein acting as a BMP-regulated transcriptional activator., Nature 1996 |
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Most Recent |
Wip1 regulates Smad4 phosphorylation and inhibits TGF-β signaling., EMBO Rep 2020 |
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All | View All Papers 19 paper(s) referencing morpholinos 3 paper(s) referencing OMIMs 6 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 8 terms | 7 terms | 7 terms | |||||
PANTHER | smad4.2 | |||||||
KEGG Pathways | K04501 | K04501 | ||||||
KOG |
[TK] TGFbeta receptor signaling protein SMAD and related proteins
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | smad4.2 | |||||||
Antibodies | Smad4 Ab1 | Smad4 Ab1 | Smad4 Ab1 | |||||
Morpholinos | smad4.2 MO1 , smad4.2 MO2 , smad4.2 MO3 | smad4.2 MO1 , smad4.2 MO2 , smad4.2 MO3 | smad4.2 MO1 , smad4.2 MO2 , smad4.2 MO3 | |||||
ORFs | smad4.2.S ORF1 | |||||||
Clones | Horizon Source BioScience | Horizon Source BioScience | Horizon Source BioScience | |||||
Plasmids | Addgene | Addgene |
Symbol legend:



