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Summary Expression Gene Literature (10) GO Terms (18) Nucleotides (204) Proteins (34) Interactants (224) Wiki
XB-GENEPAGE-6041868
Gene Symbol:
col4a5

Gene Name:
collagen, type IV, alpha 5

Synonyms:
ats , asln , ca54 ( Add synonyms , Nomenclature history )

Gene Function:
Collagens (type IV and type XIII), and related proteins

Protein Function :
Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.


InterPro :
Serralysin-like metalloprot C , CTDL fold , Collagen IV NC , Collagen [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
X-linked Alport syndrome

OMIM:
ALPORT SYNDROME 1, X-LINKED; ATS1

External Links:
 
Xenbase Gene ID XB-GENE-6041869 XB-GENE-17331745 XB-GENE-6486725
Gene Symbol col4a5 col4a5.L col4a5.S
Chromosome Chr8 chr8L chr8S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100492984
108698395
108700098
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. NCBI Protein NCBI Protein  More.. NCBI Protein
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine col4a5 col4a5.L col4a5.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards COL4A5 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Col4a5 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Col4a5 Ensembl
zebrafish
ZFIN, AGR col4a5 ZFIN Ensembl
chicken
GEISHA COL4A5 Ensembl
fruit fly
Publications
First Andersen-Tawil syndrome: new potassium channel mutations and possible phenotypic variation., Neurology 2005  
Most Recent Amphetamine enantiomers inhibit homomeric α7 nicotinic receptor through a competitive mechanism and within the intoxication levels in humans., Neuropharmacology 2019  
All View All Papers 3 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 17 terms 4 terms 0 term
PANTHER col4a5
KEGG Pathways K22669
KOG [W] Collagens (type IV and type XIII), and related proteins
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks col4a5
Clones Horizon Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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