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Summary Expression Gene Literature (9) GO Terms (7) Nucleotides (40) Proteins (22) Interactants (212) Wiki
XB-GENEPAGE-6048920
Gene Symbol:
gmnc

Gene Name:
geminin coiled-coil domain containing

Synonyms:
xgemc1 , gemc1 ( Add synonyms , Nomenclature history )

Gene Function:


Protein Function :
Regulator of DNA replication. Promotes initiation of chromosomal DNA replication by mediating topbp1- and cdk2-dependent recruitment of cdc45l onto replication origins.


Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-6048921 XB-GENE-17332996 XB-GENE-6465509
Gene Symbol gmnc gmnc.L gmnc.S
Chromosome Chr05 chr5L chr5S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100496151
108716972
100379535
mRNA NCBI Nucleotide NCBI Nucleotide RefSeq
Protein NCBI Protein NCBI Protein RefSeq Swiss-Prot
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine gmnc gmnc.L gmnc.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards GMNC OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Gmnc MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Gmnc Ensembl
zebrafish
gmnc Ensembl
chicken
GEISHA GMNC Ensembl
fruit fly
worm
Publications
First GEMC1 is a TopBP1-interacting protein required for chromosomal DNA replication., Nat Cell Biol 2010          
Most Recent Mcidas mutant mice reveal a two-step process for the specification and differentiation of multiciliated cells in mammals., Development 2019  
All View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 5 terms 3 terms 5 terms
PANTHER gmnc
KEGG Pathways
KOG
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks gmnc
Morpholinos gmnc MO1 , gmnc MO2 , gmnc MO4 gmnc MO1 , gmnc MO2 , gmnc MO4 gmnc MO1 , gmnc MO2 , gmnc MO4
Clones Horizon Source BioScience Horizon Horizon Source BioScience

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