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Summary Expression Gene Literature (56) GO Terms (7) Nucleotides (42) Proteins (23) Interactants (212) Wiki
XB-GENEPAGE-6048920
Gene Symbol:
gmnc

Gene Name:
geminin coiled-coil domain containing

Synonyms:
xgemc1 , gemc1 ( Add synonyms , Nomenclature history )

Gene Function:


Protein Function :
Regulator of DNA replication. Promotes initiation of chromosomal DNA replication by mediating topbp1- and cdk2-dependent recruitment of cdc45l onto replication origins.


Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-6048921 XB-GENE-17332996 XB-GENE-6465509
Gene Symbol gmnc gmnc.L gmnc.S
Chromosome Chr5 chr5L chr5S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100496151
108716972
100379535
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein TrEMBL NCBI Protein TrEMBL RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine gmnc gmnc.L gmnc.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards GMNC OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Gmnc MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Gmnc Ensembl
zebrafish
gmnc Ensembl
chicken
GEISHA GMNC Ensembl
fruit fly
worm
Publications
First GEMC1 is a TopBP1-interacting protein required for chromosomal DNA replication., Nat Cell Biol 2010          
Most Recent Conservation as well as divergence in Mcidas function underlies the differentiation of multiciliated cells in vertebrates., Dev Biol 2020  
All View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 5 terms 3 terms 5 terms
PANTHER gmnc
KEGG Pathways
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks gmnc
Morpholinos gmnc MO1 , gmnc MO2 , gmnc MO4 gmnc MO1 , gmnc MO2 , gmnc MO4 gmnc MO1 , gmnc MO2 , gmnc MO4
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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