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Summary Expression Gene Literature (7) GO Terms (10) Nucleotides (49) Proteins (15) Interactants (238) Wiki
XB-GENEPAGE-6050973
Gene Symbol:
trabd2a

Gene Name:
TraB domain containing 2A

Synonyms:
tiki1 , c2orf89 ( Add synonyms , Nomenclature history )

Gene Function:


Protein Function :
Metalloprotease that acts as a negative regulator of the Wnt signaling pathway: expressed in the Spemann-Mangold organizer and is required for anterior-neural patterning in head formation in embryos. A...[+]



Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-6050964 XB-GENE-17331876 XB-GENE-6488536
Gene Symbol trabd2a trabd2a.L trabd2a.S
Chromosome Chr01 Scaffold14253
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 6.0
CDS Gene model
Entrez Gene 100491951
mRNA RefSeq
Protein RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine trabd2a trabd2a.L trabd2a.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards TRABD2A OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
rat
zebrafish
ZFIN, AGR trabd2a ZFIN Ensembl
chicken
GEISHA TRABD2A Ensembl
fruit fly
Publications
First Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation., Cell 2012                        
Most Recent Establishing embryonic territories in the context of Wnt signaling., Int J Dev Biol 2021        
All View All Papers 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 10 terms 0 term 0 term
PANTHER trabd2a
KEGG Pathways
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks trabd2a
Clones Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info