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Summary Expression Gene Literature (880) GO Terms (11) Nucleotides (406) Proteins (38) Interactants (3550) Wiki
XB-GENEPAGE-6052813

Gene Symbol: myc

Gene Name: MYC proto-oncogene, bHLH transcription factor

Synonyms: c-myc , cmyc , Xcmyc , X-cmyc , myc-b , myc-a ( Add Xenopus synonyms , Nomenclature history )

Gene Function: transcription factor

Protein Function :
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.

Interactants: Loading ...
Disease Ontology: Burkitt lymphoma

OMIM Diseases: BURKITT LYMPHOMA; BL

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Xenbase Gene ID XB-GENE-6052814 XB-GENE-6256575 XB-GENE-6053022
Gene Symbol myc myc.L myc.S
Chromosome Chr06 chr6L chr6S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq TrEMBL Refseq Swiss-Prot Swiss-Prot Refseq TrEMBL Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine myc myc.L myc.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards MYC OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Myc MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR myca mycb ZFIN Ensembl
chicken
GEISHA MYC Ensembl
fruit fly
FLYBASE Myc Ensembl
worm
WORMBASE
Publications
First Accurate and efficient transcription of human c-myc genes injected into Xenopus laevis oocytes., Mol Cell Biol 1985  
Most Recent A deficiency in SUMOylation activity disrupts multiple pathways leading to neural tube and heart defects in Xenopus embryos., BMC Genomics 2019                
All View All Papers 177 paper(s) referencing morpholinos 22 paper(s) referencing OMIMs 25 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 9 terms 6 terms 4 terms
PANTHER myc
KEGG Pathways K04377 K04377 K04377
KOG
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones     EXRC - 1 clone(s)
Dharmacon Dharmacon Dharmacon
Antibody Myc Ab5 , Myc Ab12 , Myc Ab9 , Myc Ab1 , Myc Ab2 , Myc Ab3 , Myc Ab4 , Myc Ab6 , Myc Ab7 , Myc Ab8 , myc Ab10 Myc Ab5 , Myc Ab12 , Myc Ab9 , Myc Ab1 , Myc Ab2 , Myc Ab3 , Myc Ab4 , Myc Ab6 , Myc Ab7 , Myc Ab8 , myc Ab10 Myc Ab5 , Myc Ab12 , Myc Ab9 , Myc Ab1 , Myc Ab2 , Myc Ab3 , Myc Ab4 , Myc Ab6 , Myc Ab7 , Myc Ab8 , myc Ab10
Morpholino myc MO1 , myc MO2 , myc MO3 myc MO1 , myc MO2 , myc MO3 myc MO1 , myc MO2 , myc MO3
ORF myc ORF1 myc.L ORF1 myc.S ORF1 , myc.S ORF2
Affymetrix 1.0 Str.1141.1.S2_at [+] Xl.1155.2.S1_x_at [+] Xl.826.3.S1_x_at [+]
Affymetrix 2.0 Xl2.1155.2.S1_x_at [+] Xl2.826.3.S1_x_at [+]

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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