Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (771) GO Terms (6) Nucleotides (400) Proteins (37) Interactants (2656) Wiki
XB-GENEPAGE- 6052813

Gene Symbol: myc

Gene Name: MYC proto-oncogene, bHLH transcription factor

Synonyms: c-myc , cmyc , Xcmyc , X-cmyc , myc-b , myc-a
Add Xenopus synonyms , Nomenclature history


Gene Function: transcription factor

Protein Function:
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.


Interactants: Loading ...

OMIM Disease Associations: BURKITT LYMPHOMA; BL
1/3
 
Xenbase Gene ID XB-GENE-6052814 XB-GENE-6256575 XB-GENE-6053022
Gene Symbol myc myc.L myc.S
Chromosome scaffold_6 chr6L chr6S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq TrEMBL Refseq Swiss-Prot Refseq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.1141 [+] Xl.1155 Xl.826 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 84 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine myc myc.L myc.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards MYC OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Myc MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN ZFIN myca mycb ZFIN Ensembl
chicken
GEISHA MYC Ensembl
fruit fly
FLYBASE Myc Ensembl
worm
WORMBASE
Publications
First: Accurate and efficient transcription of human c-myc genes injected into Xenopus laevis oocytes. [Mol Cell Biol 1985]
Most recent: PFKFB4 control of AKT signaling is essential for premigratory and migratory neural crest formation. [Development 2017]
View All Papers 173 paper(s) referencing morpholinos 7 paper(s) referencing OMIMs
Functional Ontologies tropicalis laevis.L laevis.S
GO 3 terms 6 terms 3 terms
EC
PANTHER myc
KEGG Pathways K04377 K04377 K04377
KOG
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones     EXRC - 1 clone(s)
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Antibody Myc Ab5 , Myc Ab1 , Myc Ab2 , Myc Ab3 , Myc Ab4 , Myc Ab6 , Myc Ab7 , Myc Ab8 , Myc Ab9 , myc Ab10 Myc Ab5 , Myc Ab1 , Myc Ab2 , Myc Ab3 , Myc Ab4 , Myc Ab6 , Myc Ab7 , Myc Ab8 , Myc Ab9 , myc Ab10 Myc Ab5 , Myc Ab1 , Myc Ab2 , Myc Ab3 , Myc Ab4 , Myc Ab6 , Myc Ab7 , Myc Ab8 , Myc Ab9 , myc Ab10
Morpholino myc MO1 , myc MO2 , myc MO3 myc MO1 , myc MO2 , myc MO3 myc MO1 , myc MO2 , myc MO3
ORF myc ORF2 myc ORF3 , myc ORF1
Affymetrix 1.0 Str.1141.1.S2_at [+] Xl.1155.2.S1_x_at [+] Xl.826.3.S1_x_at [+]
Affymetrix 2.0 Xl2.1155.2.S1_x_at [+] Xl2.826.3.S1_x_at [+]

Symbol legend[+]

My Xenbase: [ Log-in / Register ]
version: [4.6.0]

Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556