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Summary Expression Gene Literature (5292) GO Terms (11) Nucleotides (426) Proteins (60) Interactants (3711) Wiki
XB-GENEPAGE-6052813
Gene Symbol:
myc

Gene Name:
MYC proto-oncogene, bHLH transcription factor

Synonyms:
c-myc , cmyc , Xcmyc , X-cmyc , myc-b , myc-a ( Add synonyms , Nomenclature history )

Gene Function:
transcription factor

Protein Function :
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.


InterPro :
TRPM7 , Kinase-like dom sf , MHCK EF2 kinase , TRPM tetra sf [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
Burkitt lymphoma

OMIM:
BURKITT LYMPHOMA; BL

External Links:
1/4
 
Xenbase Gene ID XB-GENE-6052814 XB-GENE-6256575 XB-GENE-6053022
Gene Symbol myc myc.L myc.S
Chromosome Chr6 chr6L chr6S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 395024
399315
379052
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine myc myc.L myc.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards MYC OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Myc MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Myc Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR myca mycb ZFIN Ensembl
chicken
GEISHA MYC Ensembl
fruit fly
FLYBASE Myc Ensembl
worm
Publications
First Accurate and efficient transcription of human c-myc genes injected into Xenopus laevis oocytes., Mol Cell Biol 1985  
Most Recent Tbx2 mediates dorsal patterning and germ layer suppression through inhibition of BMP/GDF and Activin/Nodal signaling., BMC Mol Cell Biol 2020                
All View All Papers 179 paper(s) referencing morpholinos 22 paper(s) referencing OMIMs 27 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 10 terms 5 terms 6 terms
PANTHER myc
KEGG Pathways K04377 K04377 K04377
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks myc
Antibodies Myc Ab5 , Myc Ab12 , Myc Ab9 , Myc Ab1 , Myc Ab2 , Myc Ab3 , Myc Ab4 , Myc Ab6 , Myc Ab7 , Myc Ab8 , myc Ab10 Myc Ab5 , Myc Ab12 , Myc Ab9 , Myc Ab1 , Myc Ab2 , Myc Ab3 , Myc Ab4 , Myc Ab6 , Myc Ab7 , Myc Ab8 , myc Ab10 Myc Ab5 , Myc Ab12 , Myc Ab9 , Myc Ab1 , Myc Ab2 , Myc Ab3 , Myc Ab4 , Myc Ab6 , Myc Ab7 , Myc Ab8 , myc Ab10
Morpholinos myc MO1 , myc MO2 , myc MO3 myc MO1 , myc MO2 , myc MO3 myc MO1 , myc MO2 , myc MO3
ORFs myc ORF1 myc.L ORF1 myc.S ORF1 , myc.S ORF2
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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