Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (180) GO Terms (23) Nucleotides (122) Proteins (44) Interactants (579) Wiki
XB-GENEPAGE-6053488
Gene Symbol:
fyn

Gene Name:
FYN proto-oncogene, Src family tyrosine kinase

Synonyms:
c-fyn , syn , slk , fyn-a , fyn-b ( Add synonyms , Nomenclature history )

Gene Function:
tyrosine kinase

Protein Function :
Tyrosine-protein kinase implicated in the control of cell growth. Plays a role in the regulation of intracellular calcium levels. Required in brain development and mature brain function with important ...[+]


InterPro :
GPCR 3 Ca sens rcpt-rel , GPCR 3 CS , GPCR 3 9-Cys sf , GPCR 3 vmron rcpt 2 [+]

Interactants:
Loading ...

Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-6053489 XB-GENE-6252893 XB-GENE-6053528
Gene Symbol fyn fyn.L fyn.S
Chromosome Chr5 chr5L chr5S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100488004
373609
379812
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine fyn fyn.L fyn.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards FYN OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Fyn MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Fyn Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR fyna fynb ZFIN Ensembl
chicken
GEISHA FYN Ensembl
fruit fly
worm
Publications
First Structure and expression of fyn genes in Xenopus laevis., Oncogene 1990  
Most Recent Uroplakins play conserved roles in egg fertilization and acquired additional urothelial functions during mammalian divergence., Mol Biol Cell 2018                    
All View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 21 terms 4 terms 2 terms
PANTHER fyn
KEGG Pathways K05703 K05703
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks fyn
Antibodies Fyn Ab1 Fyn Ab1 Fyn Ab1
ORFs fyn.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list