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Summary Expression Gene Literature (51) GO Terms (2) Nucleotides (18) Proteins (4) Interactants (250) Wiki
XB-GENEPAGE-6054494
Gene Symbol: ptpn11

Gene Name: protein tyrosine phosphatase, non-receptor type 11

Synonyms: cfc , shp2 , bptp3 , ptp2c , ns1 , shp-2 , ptp-2 , ptpn11-a , ptpn11-b ( Add synonyms , Nomenclature history )

Gene Function:

Protein Function :

Interactants: Loading ...
Disease Ontology: juvenile myelomonocytic leukemia [+]

OMIM Diseases: JUVENILE MYELOMONOCYTIC LEUKEMIA; JMML [+]

 
Xenbase Gene ID XB-GENE-22063677 XB-GENE-22063678 XB-GENE-6254179
Gene Symbol ptpn11 ptpn11.L ptpn11.S
Chromosome Scaffold219188
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence
CDS
Entrez Gene
mRNA RefSeq
Protein RefSeq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine ptpn11 ptpn11.L ptpn11.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards PTPN11 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Ptpn11 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR ptpn11b ptpn11a ZFIN Ensembl
chicken
GEISHA PTPN11 Ensembl
fruit fly
worm
WORMBASE
Publications
First Synthesis of an ochre suppressor tRNA gene and expression in mammalian cells., EMBO J 1984  
Most Recent A YWHAZ Variant Associated With Cardiofaciocutaneous Syndrome Activates the RAF-ERK Pathway., Front Physiol 2019                    
All View All Papers 6 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 0 term 0 term 2 terms
PANTHER ptpn11
KEGG Pathways K07293
KOG
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon
Antibody Ptpn11 Ab1
ORF ptpn11.S ORF1
Affymetrix 1.0 Xl.936.1.S1_at
Affymetrix 2.0 Xl2.936.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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