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Summary Expression Gene Literature (33) GO Terms (9) Nucleotides (115) Proteins (27) Interactants (466) Wiki
XB-GENEPAGE- 6085858

Gene Symbol: mafb

Gene Name: v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B

Synonyms: kreisler , xmafb , valentino
Add Xenopus synonyms , Nomenclature history


Gene Function: basic leucine zipper (bZIP) transcription factor

Protein Function :
Acts as a transcriptional activator or repressor. Implicated in the regulation of cell-type specific gene expression and play a role in inductive events during lens development.


Interactants: Loading ...

Disease Ontology:
  

OMIM Diseases:
   MULTICENTRIC CARPOTARSAL OSTEOLYSIS SYNDROME; MCTO [+]
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Xenbase Gene ID XB-GENE-6085859 XB-GENE-17334208 XB-GENE-6085884
Gene Symbol mafb mafb.L mafb.S
Chromosome Chr10 chr9_10L chr9_10S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq NCBI Nucleotide Refseq
Protein Refseq Swiss-Prot NCBI Protein TrEMBL Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.10135 Xl.19807
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 74 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine mafb mafb.L mafb.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards MAFB OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Mafb MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR mafba mafbb ZFIN Ensembl
chicken
GEISHA MAFB Ensembl
fruit fly
worm
WORMBASE
Publications
First: Segmental regulation of Hoxb-3 by kreisler. [Nature 1997]
Most recent: Genome-wide transcriptomics analysis identifies sox7 and sox18 as specifically regulated by gata4 in cardiomyogenesis. [Dev Biol 2018]
View All Papers 5 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 9 terms 5 terms 6 terms
PANTHER mafb
KEGG Pathways K09036 K09036 K09036
KOG
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones     EXRC - 3 clone(s)
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Morpholino mafb MO1 mafb MO1 mafb MO1
Affymetrix 1.0 Str.10135.1.S2_at Xl.24839.1.S1_at
Affymetrix 2.0 Xl2.24839.1.S2_x_at [+]

Symbol legend[+]
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Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556