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Summary Expression Gene Literature (27) GO Terms (10) Nucleotides (223) Proteins (18) Interactants (271) Wiki
XB-GENEPAGE- 5899284

Gene Symbol: gap43

Gene Name: growth associated protein 43

Synonyms: b-50 , pp46 , neuromodulin , gap43-b , gap43-a
Add Xenopus synonyms , Nomenclature history

Gene Function: Receptor-activated Ca2+-permeable cation channels (STRPC family)

Protein Function :
This protein is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.

Interactants: Loading ...

Disease Ontology:

OMIM Diseases:

Xenbase Gene ID XB-GENE-5899285 XB-GENE-6255794 XB-GENE-5899429
Gene Symbol gap43 gap43.L gap43.S
Chromosome Chr02 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq TrEMBL TrEMBL TrEMBL Refseq TrEMBL Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.21887 Xl.9994 Xl.1133
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 6 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine gap43 gap43.L gap43.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
MOD Entrez Gene Genetic Phenotypes Gene Expression
OMIM:Gene, HGNC, GeneCards GAP43 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
MGI, AGR Gap43 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
ZFIN, AGR gap43 ZFIN Ensembl
GEISHA GAP43 Ensembl
fruit fly
First: Cloning and embryonic expression of Xenopus laevis GAP-43 (XGAP-43). [Dev Biol 1995]
Most recent: Quantitative Proteomics After Spinal Cord Injury (SCI) in a Regenerative and a Nonregenerative Stage in the Frog Xenopus laevis. [Mol Cell Proteomics 2018]
View All Papers 10 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 3 terms 1 terms 8 terms
KEGG Pathways K20041 K20041 K20041
KOG [PT] Receptor-activated Ca2+-permeable cation channels (STRPC family)
Reagents tropicalis laevis.L laevis.S
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Antibody Gap43 Ab1 Gap43 Ab1 Gap43 Ab1
ORF gap43 ORF1 , gap43 ORF1 gap43.L ORF1 gap43.S ORF1
Affymetrix 1.0 Str.21887.1.S2_at Xl.9994.1.S1_at [+] Xl.1133.1.S1_at
Affymetrix 2.0 Xl2.9994.1.S1_at [+] Xl2.1133.1.S1_at

Symbol legend[+]
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Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556