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Summary Expression Gene Literature (37) GO Terms (21) Nucleotides (216) Proteins (17) Interactants (938) Wiki
XB-GENEPAGE-6257418
Gene Symbol: tbx6

Gene Name: T-box 6

Synonyms: dfnb67 , XTbx6 ( Add synonyms , Nomenclature history )

Gene Function: transcriptional activator

Protein Function :
Transcriptional activator. Plays a role in ventral mesoderm specification and acts together with nog during muscle differentiation. Mediates posterior pattern formation of the embryo, including specifi...[+]

Interactants: Loading ...
Diseases:  OMIM: SPONDYLOCOSTAL DYSOSTOSIS 5; SCDO5

External Disease Links: ClinVar, MalaCards, KEGG Disease, DECIPHER
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Xenbase Gene ID XB-GENE-6257419 XB-GENE-6254214 XB-GENE-17335269
Gene Symbol tbx6 tbx6.L tbx6.S
Chromosome scaffold_1489 Scaffold22 Scaffold29
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 4.1 Version 9.1 Version 9.2
CDS Gene model
Entrez Gene 493357
394428
108704289
mRNA RefSeq RefSeq NCBI Nucleotide
Protein RefSeq Swiss-Prot RefSeq Swiss-Prot TrEMBL Swiss-Prot NCBI Protein
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine tbx6 tbx6.L tbx6.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tgas124n10      
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards TBX6 OMIM Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Tbx6 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR tbx16l ZFIN Ensembl
chicken
GEISHA TBX6 Ensembl
fruit fly
worm
WORMBASE
Publications
First Characterization of the zebrafish tbx16 gene and evolution of the vertebrate T-box family., Dev Genes Evol 1998  
Most Recent Innate Immune Response and Off-Target Mis-splicing Are Common Morpholino-Induced Side Effects in Xenopus., Dev Cell 2018                              
All View All Papers 9 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 19 terms 12 terms 0 term
PANTHER tbx6
KEGG Pathways K10180 K10180
KOG
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks
Morpholinos tbx6 MO1 , tbx6 MO2 , tbx6 MO3 , tbx6 MO4 , tbx6 MO5 , tbx6 MO6 tbx6 MO1 , tbx6 MO2 , tbx6 MO3 , tbx6 MO4 , tbx6 MO5 , tbx6 MO6 tbx6 MO1 , tbx6 MO2 , tbx6 MO3 , tbx6 MO4 , tbx6 MO5 , tbx6 MO6
ORFs tbx6 ORF1
Clones Horizon Source BioScience Horizon Horizon

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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Version: 4.13.1
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