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Summary Expression Gene Literature (39) GO Terms (25) Nucleotides (218) Proteins (18) Interactants (950) Wiki
XB-GENEPAGE-6257418
Gene Symbol:
tbx6

Gene Name:
T-box 6

Synonyms:
dfnb67 , XTbx6 ( Add synonyms , Nomenclature history )

Gene Function:
transcriptional activator

Protein Function :
Transcriptional activator. Plays a role in ventral mesoderm specification and acts together with nog during muscle differentiation. Mediates posterior pattern formation of the embryo, including specifi...[+]


InterPro :
T-box sf , p53-like TF DNA-bd , TF T-box CS , TF T-box

Interactants:
Loading ...

Diseases: 


Disease Ontology:
spondylocostal dysostosis

OMIM:
SPONDYLOCOSTAL DYSOSTOSIS 5; SCDO5

External Links:
1/4
 
Xenbase Gene ID XB-GENE-6257419 XB-GENE-6254214 XB-GENE-17335269
Gene Symbol tbx6 tbx6.L tbx6.S
Chromosome Chr9 Scaffold22 Scaffold29
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model
Entrez Gene 493357
394428
108704289
mRNA RefSeq RefSeq NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. NCBI Protein NCBI Protein
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine tbx6 tbx6.L tbx6.S
Phenotype X. tropicalis X. laevis.L X. laevis.S
Smith Morpholino Screen tgas124n10      
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards TBX6 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Tbx6 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Tbx6 Ensembl
zebrafish
ZFIN, AGR tbx16l ZFIN Ensembl
chicken
GEISHA TBX6 Ensembl
fruit fly
Publications
First Characterization of the zebrafish tbx16 gene and evolution of the vertebrate T-box family., Dev Genes Evol 1998  
Most Recent Xenopus gpx3 Mediates Posterior Development by Regulating Cell Death during Embryogenesis., Antioxidants (Basel) 2020            
All View All Papers 9 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 23 terms 12 terms 0 term
PANTHER tbx6
KEGG Pathways K10180 K10180
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks
Antibodies Tbx6 Ab1
Morpholinos tbx6 MO5 , tbx6 MO6 , pou5f3.3 MO8
ORFs tbx6 ORF1
Clones Horizon Source BioScience Horizon Horizon
Plasmids Addgene Addgene

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