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Summary Expression Gene Literature (37) GO Terms (13) Nucleotides (202) Proteins (7) Interactants (916) Wiki
XB-GENEPAGE- 6257418

Gene Symbol: tbx6

Gene Name: T-box 6

Synonyms: dfnb67 , XTbx6
Add Xenopus synonyms , Nomenclature history

Gene Function: transcriptional activator

Protein Function :
Transcriptional activator. Plays a role in ventral mesoderm specification and acts together with nog during muscle differentiation. Mediates posterior pattern formation of the embryo, including specifi...[+]


Interactants: Loading ...

Disease Ontology:
  

OMIM Diseases:
   SPONDYLOCOSTAL DYSOSTOSIS 5; SCDO5
1/4
 

Xenbase Gene ID XB-GENE-6257419 XB-GENE-6254214 XB-GENE-17335269
Gene Symbol tbx6 tbx6.L tbx6.S
Chromosome scaffold_1489 Scaffold22 Scaffold29
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence
CDS
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Swiss-Prot Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus PANTHER
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.1637 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 25 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine tbx6 tbx6.L tbx6.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tgas124n10      
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards TBX6 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Tbx6 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR tbx16l ZFIN Ensembl
chicken
GEISHA TBX6 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Characterization of the zebrafish tbx16 gene and evolution of the vertebrate T-box family. [Dev Genes Evol 1998]
Most recent: Innate Immune Response and Off-Target Mis-splicing Are Common Morpholino-Induced Side Effects in Xenopus. [Dev Cell 2018]
View All Papers 9 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 13 terms 13 terms 0 term
PANTHER tbx6
KEGG Pathways K10180 K10180
KOG
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience
Morpholino tbx6 MO1 , tbx6 MO2 , tbx6 MO3 , tbx6 MO4 , tbx6 MO5 , tbx6 MO6 tbx6 MO1 , tbx6 MO2 , tbx6 MO3 , tbx6 MO4 , tbx6 MO5 , tbx6 MO6 tbx6 MO1 , tbx6 MO2 , tbx6 MO3 , tbx6 MO4 , tbx6 MO5 , tbx6 MO6
ORF tbx6 ORF1 , tbx6 ORF1
Affymetrix 1.0 Str.1637.1.S1_at Xl.9564.1.A1_at
Affymetrix 2.0 Xl2.9564.1.A1_at

Symbol legend[+]
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