Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (2) GO Terms (7) Nucleotides (90) Proteins (32) Interactants (7) Wiki
XB-GENEPAGE-6258150
Gene Symbol:
ada2

Gene Name:
adenosine deaminase 2

Synonyms:
idgfl , adgf , cecr1-a , cecr1-b , cecr1 ( Add synonyms , Nomenclature history )

Gene Function:


Protein Function :
Adenosine deaminase that may contribute to the degradation of extracellular adenosine, a signaling molecule that controls a variety of cellular responses. Stimulates cell proliferation.



Interactants:
Loading ...

Diseases: 


Disease Ontology:
Sneddon syndrome [+]

OMIM:
SNEDDON SYNDROME; SNDNS [+]

External Links:
 
Xenbase Gene ID XB-GENE-6258151 XB-GENE-6254244 XB-GENE-6251688
Gene Symbol ada2 ada2.L ada2.S
Chromosome Chr3 Scaffold27697 chr3S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 6.0 Version 9.2
CDS Gene model Gene model
Entrez Gene 100487564
779128
734202
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein RefSeq Swiss-Prot  More.. NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine ada2 ada2.L ada2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards ADA2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
rat
zebrafish
ZFIN, AGR ZFIN, AGR ada2a ada2b ZFIN Ensembl
chicken
GEISHA CECR1 Ensembl
fruit fly
Publications
First The extracellular adenosine deaminase growth factor, ADGF/CECR1, plays a role in Xenopus embryogenesis via the adenosine/P1 receptor., J Biol Chem 2008  
Most Recent Histone H3 tail acetylation modulates ATP-dependent remodeling through multiple mechanisms., Nucleic Acids Res 2011                
All View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 0 term 6 terms 4 terms
PANTHER ada2
KEGG Pathways K19572 K19572
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks ada2
Morpholinos cecr1 MO1 , cecr1 MO3 , cecr1 MO2
ORFs ada2.L ORF1
Clones Horizon Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info