[provisional- machine annotated only] Gene Symbol: cbl [Predicted: Source is Human Entrez Gene] Gene Name: Cbl proto-oncogene, E3 ubiquitin protein ligase [Predicted: Source is Human Entrez Gene] Synonyms: c-cbl, rnf55 Add Xenopus synonyms Gene Function: Interactants: akt1(5) , ppp3ca(4) , abl1(1) , dab2ip(1) , egfr(1) , fgf2(1) , magi2(1) View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001128638|Xenopus (Silurana) tropicalis Cas-Br-M (murine) ecotropic retroviral transforming sequence (cbl), mRNA CGTTCTCGCTTGAGAAAAGGCGGAAGTGACGGCGGCGGCGCGGTGCTCGGCCCCGGGAGAATCATCTCCCCCTCCCAGCCCGGCGCACACAGGGAGGGCTGTGTCCGGGGGCCCCGTGTTCACCAGCCGCAGGAATTCCACCCTGCTGCTCCACGCTCACTGGTCACCATGGCGACCAACCTGCGAAAGGGCGGCGGGTTGATCGGGCTGGTGAAAGATGCTTTCCAGCCCCACCATCACCATCCGACTGCGCAGCCGGGGGCTGTGGACCGGAAGACGGTGGAGAAATGCTGGAAACTCATGGATAAGGTTGTTCGGTTGTGCCAGAATCAAAGGCTAGCTCTGAAGAATAGCCCTCCTTACATTCTAGACCTGCTTCCTGACACTTATCAACACCTTCGGACCATTATGTCCCGATATGAGGGGAAAATGGAGATTCTGGGAGAGAACGAATATTTTCGTGTTTTCATGGAAAACCTCTTGAAGAAGACCAAACAAACAATTAGCCTCTTTAAAGAGGGCAAAGAACGCATGTACGAGGAAAATTCTCAGCCAAGAAGGAACTTGACAAAATTATCACTCATCTTTAGTCACATGCTGGCAGAGCTGAAAGCTATCTTCCCTAATGGACAGTTCCAAGGAGATTCATTCCGAATCACAAAGGCAGATGCAGCAGAATTCTGGCGGAAAGCATTTGGAGAGAAAACTATAGTCCCCTGGAAGATTTTCCGTCTTGCACTGCATGATGTTCACCCAATCTCCTCTGGACTGGAAGCCATGGCTTTGAAATCCACAATTGACCTCACATGCAATGATTATATCTCTGTATTTGAGTTTGATATCTTTACCCGGCTTTTTCAGCCATGGTCCTCCCTTCTCAGGAACTGGAATAGTTTGGCAGTAACACACCCTGGATACATGGCCTTTCTGACGTATGATGAGGTCAAAGCTCGGCTGCAGAAATTCATCCACAAACCTGGGAGTTACATTTTTCGTCTGAGCTGCACGCGGCTAGGTCAGTGGGCTATTGGATATGTCACAGGCGATGGAAATATTTTACAGACCATCCCACACAACAAACCACTCTTCCAAGCACTGATCGATGGCTTCCGGGAAGGATTTTACCTCTTCCCTGATGGGCGCAACCAAAACCCAGATCTGACAGGCTTGTGTGAGCCCACTCCTCAGGACCACATCAAAGTCACTCAGGAGCAATATGAGCTGTACTGTGAGATGGGCTCCACCTTCCAGCTCTGCAAGATTTGTGCTGAGAATGACAAGGATGTTAAAATTGAGCCCTGTGGGCATCTAATGTGCACATCATGCCTCACCTCCTGGCAGGAATCTGAGGGGCAGGGCTGTCCTTTCTGTCGCTGTGAAATCAAAGGAACGGAGCCCATCGTCGTGGATCCCTTCGACCCAAGAGGTGGTGGTATGGCAGAATTGCTACGGCACTGTATGGATGGAACCCCTTCTCCTTGCTATGATGATGATGATGACGATAGTGGAAATGACTCTATCTTTGTGATGAAAGAATTGGCAGGTGCCAAGGTGGAAAGACCTCCTTCACCACTGTCTGCCACCCCACAAGCCTCACTTCCCCCTGTGCCTCCCCGTCTAGACCTGTTGCCACAGAGAGCACCCAATCAATCTGGCGCTTGCAGTCCAGCAACAAGTTCCAAGGCTTCCAGCAGTTCACACCACAAGGATAAACCTTTGCCCGTGCCCCCAACTCTGCGAGACCTTCCGCCTCCACCGCCCCCAGACAGACCTCACTCTATGCCATGTGAAAGCAGGCCTCAGAGGAGACCTCTTCCCTCTACCCCTGCAGAAAAGCCCCTTCCATTACCCACTAATCGACCTGGAGAAACCTGGCATCCACGTGCTGTTCCGAAAGCACCTGCCTCTAATTTGACTCCTGGTGACCCTTGGACTGGGGGAAGAGAGTTGACAAATCGACATTCTCTGCCTTTTACACTGCCTTCACACATTGATGAGAGGAGAGACCGACATGGAAGCACACAAAGCTTGGACAACACAGGCATAAGTGCCACCACAGAGTTATTTGGAGGACTAGATAATGATGATGCCAAAATGAAGCCATCCTCATCTGCAAATGCCATTTACTCTTTGGCCACCAGGCCTTTCCCGGTGTCAAAGCCTCCAACAGGGGATCATGTTGACAGTGGAGATGAGTCTGAATATATGTGTCCTTCATCAAGGCCCTTGATTCCTGCAGCAGTACCAAAATCTGAAGCCAGGAGACCACTAGAGACATTACCTGGCTTGCGGCCACCAGATCAGCAGACTGAAAGGGAGTCCTATGAAACCATGTACAATATCCAGTGCCAAGCTACCAATCCAGTTGTTGTGGAGCCCAGCAGGGAAGAAGAAACAAATTCTGCAATAGCCAACAATGGACCAGAGAACGATGACAATGAGGAAGATGGATATGACATACCGAAACCCCATTTGCCGATGGCTCCTGCCCGTCGCACCATGTCTGATGCTCCTAATGCCACACCTGCCTTCTGCTCTGGTGCCATTGGCAGGGACTCTGGAGCAGGGCTTTTGGAGTCTTCCCAGGTTCCTGAGCGTCCCCCAAAACCTTTTCCAAGGAGGATGAACTCTGAACGCAGGTCGGTAGTTGGAGGAGGTTCTGGGGATGCCCCTCCTGCACCACTATCCAGTGAGATTGAGAGCTTGCTGAGTCAAGGCTACTCCCAACAGGACGTGAACAAGGCCTTGCTCATAGCCCACAACAATATTGAAATGGCCCGCAACATCCTGCGTGAATTTGTGTCTATCCCTTCACCGGCTCATGTTGCCACATAGCATCTGTGGAACTTGGACACTCCAGCCCTAGGTGGGAAAGGGGAGGAGAGCAAGAAGAGCATACCTCCATCTCCTGGGCTTTTAAGCATCACAGGAGCAACTGTGGGACCAGTGTGGGTAGTTGTGGGTACAATGGTATTAAGAGGAGTGAGGTGCCCATAGTCCCTTACTGGAAGTAAACAGGGTATGGGCGTCAGCCTGCCCAATAACTAGAAGCATTACAAGTAATATGACCCATGGCCATATGAGCACTCCATTTAGGAATGATCAGATGCCCCATCTCTCCAATCCATTTGCTGCCTGTCTTCTAGAATTTCAGGTACATTAGGCTCGCATGGCTCTGTTTAATGTTTTGGACACATTGAACATGCTGCCAGTTAAAATAGATCTTTGAGTTGCCCACCAATGAGATGAGGGAGATCAGACGGTTATATATATTGTCATTCAATGTAATGTTTAACAACCCCTTTCATAACTGAATGGGTTTATTGGCACCTTTCTCTGCTGTTACAGAGGAACCTCACTCATTGAATGAAACTGCCTTAGGGTGAGGAACCTTTTATCACACAGGAGTAGGTGCTTTTGACCCTATTAAATGGCATTATTCAAAATGAGTTGGGTCTGCTCCCTTAGCCCTTTTTAATCCTTGTTTTGCTGTTTTTCAGTTACTGTGTGTGTATGTGTGTGTTTTTTTTTTTAACATGTGACTCAAGGCAATAAGGCACTCCAGGGTTTGGTCCCCCCACTCCCCAATATCCAGGGTGCCCTAATGCCATACAACTCAGGGTTAATGGGTGTCTCCCTCCAGGAGTGGATTAGTGGAAGCAGAATTCTGGAGGAGGTGGGAAGAATCCTTTTTCTAAAGGGTTAGGATGGTTCATGCAAGACCTATGTTAAGTACAAGCAAGTACATGCTTCTACATCAGACTGATGCTATTTCAAGTTTCACTGCCACTTAACATTTACTAGCATTAATGCATCACGTACAGAGAATAAATCCACAAACAATATTACAGATTGTGTGTAACCTATATGTGTATAATATCTATGTATATAAACGGGTATTTTTATATACATTATATATGTGTATGTATGTACATGTAAAAGCATTTATAGCTGCACCAGTTATTTCATCCCGTGTACATAAGCACGTAATGGCTTTCCCTACTCCATTCTGGGGCGAGATGAGCAACATACTATATACTTTGCCATATTCTCACACTAAGCAGCAGATTTATCAAAATTCACTATTACTTTTCGCAATTTGAAAAAAAGGCAGAGAAAAAACTCAAATATACGGAAATATTTTTAAAAACTCAAATTATTGCTTTCAATTTTTTTTTTTTTTTAAAAAGTGAATATTTGCATTAAAAACCCTGCAAGTAAAAGCTCCTGCGTTTTTATAGAAGTCGATGGGAGTGGTCTCCAAAATTTCAAGCTTTTTTTCTGTGATAAGATGCGCCTATTCTGTCTGAGGTTTTTTCTTAAATATGCTAGTGCTTGAGAATAGAAACATGCGGTTACAGAGAAAAAGTTGCTTGAGTTTTTTTTTGCATTTTTTCCCTTGATCTCAAACATTTTTGCCTTTTGAAGCTCATACACAGTCTCACTGCCAGTCTCTGTCCCTGTATCATTTTTTTTATTTCCTTACATGTCGGTGTGTGAAAGAGAAACTATTTATTTAATATTTTTTCTATAAATGTTCCATTTACCTAGAATTTATTAACAAACTGGATGCGTTTCTTCTTTTTTATGCATCCTAAAAGGTTTTCACTTAAAAAGAAGCCACAACAAATATGAAGACGTTAAAATAAAATGGAAGTATCCTTGCCACTAGTGCTTGCTTGGCCAGCTCTTTTGCTGACCTCACCCTGCTCTGCATAGATATACATATAGATACACACATCTACACGCAGCTTCTTTTTCTAAAGGTTTTTCATCTTGGTCCACTTAATTTTATAGCAGGAATACCACACATCCTTCAAGCAAATGTGAACTACAAAACTCAGATATTTTAGGCAGTTCTGGGTCTTGTAGTTCAAAACAACGAGAGGAGGAGTGAGAATAACATCCTAAAGCTGGCCATACACTGAAAGATTCTCGTCAACCGAGTGGATGTTTCCCCCCGATATACGCTATATACGACTTTGGCAATATCGGGCTGGCCAAATTATCAGATTACAGCCACGGAATTGCAGGCCGTCAGGGTGAAAAGCATATTGATGAGTCTATACTGTGCTTACCCCAACAATGCCCAATTGACATCTGGACGATTTTTGGGCAGATATCAGTTGGGCAGGCCCGTTGGAGGGCCCATACACAGGCAGATAAGCTGTCAACTAAGTTCGAATGGGCTGAATTGGCATCTTAAATCATCCAGTGTATAGCCATCATTAGTCTTTAGCATATACACACATACATGAGACCAAGTTGTGATTTTATTTGTAAGGGTTTACAAACAGAGTTCTGTGGGTTTGGCATCAGAAAGTGAAGGCTTATATTGCACCCACATTATAATCATGCATACTGTGGGGGAGAGGGCAGCCTCCTCCATATCCATGATTTAAGCAGTGTTAAAAGCTTGACAATAAATCTAACAGATTTTTTTTTATTATTATTGTATTTAATCAGGACCCCAAGGTAAATATTCTTACAAGCAAAGGGTCTGCAAATTCCCCTTGTTATGGATTTTGTTTGTATTTTAAGCCTGTGTTCTTCTAACGATTGTAGAGTATACTAAAAAAAAAAGTTATTTATTTAATGACTTTTCTTTTAACTAAAGAGCTTTTCTTATTTTATTTTCAGTTTGTTTTTCTGTACCAATTTATGGGGAAAAATATTTTTAAAATAAATTCTTTTTGTCTGTTTCAGTCTTAAAAAAAAAAAAAAAAAAAAAAAAA	NCBI Nucleotide >AF237765|Xenopus laevis Cbl proto-oncogene protein (Cbl) mRNA, partial cds GGTCGCAACCAAAACCCTGATCGTACAGGCTTGTGTGAGCCCACCCCTCAGGACCACATAAAAGTCACTCAGGAGCAATATGAGCTGTACTGTGAGATGGGCTCCACCTTCCAGCTCTGCAAGATCTGTGCTGAGAATGACAAGGATGTTAAAATTGAGCCCTGTGGGCATCTAATGTGCACATCATGCCTCACCTCCTGGCAGGAATCTGAGGGGCAGGGCTGTCCTTTCTGTCGCTGTGAAATCAAAGGAACTGAGCCCATCGTTGTGGATCCCTTTGACCCAAGATGTGGTGCTATGGCAGAATTGCTTCGGCAATGTATGGATGGAACCCCTTCGCCTTGTTATGATGATGATGACGATGATGAAGTGGAACTGACTCTTTCCTTTGTGATGAAAGAACTGGCAGGGTCCAAGGTGGAAAGACCCCCTTCTCCACTGTCTGTCACCCCACAAGCCTCACTCCCCCCTGTGCCTCCCCGTCTAGACTTGCTGCAGCAGAGGACACCTAACCAATCTGGAGCTTGCAGTCCAGCAACTAGTTCCAAGGCTTCCAGCAGTTCTCACCACAAGGATAAGCCTTTGCCTGTACCTCCAACTCTGCGAGACCTTCCGCCTCCACCACCCCCAGACAGACCTCATTCTATTGCAAGTGAGAGCAGGCCCCAGAGGAGACCTTTACCTTCTACCCCTGCAGAAAAGCCCCTTCTGTTGCCCACTAACCGACCTGGAGAAACCTGGCATCCACGTGCTGTTCCCAAAGCACCTGCCACTAATTTGACTCCTGGTGACCCTTGGACTGGTGGAAGAGAGCTGACAAATCGTCATTCTCTGCCTTTTACACTGCCTTCACACATTGATGAGAGGAGAGACCGACATGGAAGCACACAAAGCTTGGACAACACAGGCATAAGTGCAACCACAGAGTTGTTTGGAGGACTAGATAATGATGATGCCAAAATGAAGCCATCCTCATCTGCAAATGCCATTTACTCTTTGGCCACCAGGCCTTTCCCGGTGCCTCCAGTAGGGGATCATGTGGACAGTGGAGATGAGTCTGAATATATGTGTCCTTCATCAAGGCCCTTGATCCCTGCTCCAGTAGCAAAAACAGAAGCAAGGAGACCACTAGAGACAGTACCTAGCTTGTGGCCACCAGACCAGCAGACTGAAAGGGAATCCTATGAGACCATGTACAATATCCAGTGCCAAGCTACCACTCCAGTTGTTGTGGAGCCCAGCAGGGAAGGAGCAGAAACTAATTCTGCAATAGCTAACAATGGACCAGAGGATGATGACAATGAGGATGATGGATATGACATACCGAAGCCCCATTTGCCCATGGCTATTGCTCGCCGCACCCTCTCTGATGCCCCTAATGCCACACCTGCCTTCTGCCCTGGAACCATTAGCAGGGACTCCGGAGCAGGGCTTCCGGAGTCTTCTCAGGTTCCTGAGCGCCCCCCAAAACCTTTTCCAAGGAGGATGAACTCTGAACGCAGGCCAGTTGTTGGTGGAGGTTTTGGGGATGCTCCTCCTGCACCACTATCCAGCGAGATTGAAAGCTTGCTGAGTCAAGGTTACTCCCAACAGGACGTGAACAAAGCCTTGCTTATAGCCCGCAACAATATTGAAATGGCCCGTAACATCCTGCGTGAATTTGTGGCCATCCCTTCACCGGCTCATGTTGCCACATAGCAGCTGTGGAACTTGGACACTCCAGCCCTGGGTGGGAAAGGGGAGGAGAGCAAGAAGAGT
Protein		Refseq >NP_001122110|Cas-Br-M (murine) ecotropic retroviral transforming sequence [Xenopus (Silurana) tropicalis] MATNLRKGGGLIGLVKDAFQPHHHHPTAQPGAVDRKTVEKCWKLMDKVVRLCQNQRLALKNSPPYILDLLPDTYQHLRTIMSRYEGKMEILGENEYFRVFMENLLKKTKQTISLFKEGKERMYEENSQPRRNLTKLSLIFSHMLAELKAIFPNGQFQGDSFRITKADAAEFWRKAFGEKTIVPWKIFRLALHDVHPISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCTRLGQWAIGYVTGDGNILQTIPHNKPLFQALIDGFREGFYLFPDGRNQNPDLTGLCEPTPQDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQESEGQGCPFCRCEIKGTEPIVVDPFDPRGGGMAELLRHCMDGTPSPCYDDDDDDSGNDSIFVMKELAGAKVERPPSPLSATPQASLPPVPPRLDLLPQRAPNQSGACSPATSSKASSSSHHKDKPLPVPPTLRDLPPPPPPDRPHSMPCESRPQRRPLPSTPAEKPLPLPTNRPGETWHPRAVPKAPASNLTPGDPWTGGRELTNRHSLPFTLPSHIDERRDRHGSTQSLDNTGISATTELFGGLDNDDAKMKPSSSANAIYSLATRPFPVSKPPTGDHVDSGDESEYMCPSSRPLIPAAVPKSEARRPLETLPGLRPPDQQTERESYETMYNIQCQATNPVVVEPSREEETNSAIANNGPENDDNEEDGYDIPKPHLPMAPARRTMSDAPNATPAFCSGAIGRDSGAGLLESSQVPERPPKPFPRRMNSERRSVVGGGSGDAPPAPLSSEIESLLSQGYSQQDVNKALLIAHNNIEMARNILREFVSIPSPAHVAT	NCBI Protein >AAF43710|Cbl proto-oncogene protein [Xenopus laevis] GRNQNPDRTGLCEPTPQDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQESEGQGCPFCRCEIKGTEPIVVDPFDPRCGAMAELLRQCMDGTPSPCYDDDDDDEVELTLSFVMKELAGSKVERPPSPLSVTPQASLPPVPPRLDLLQQRTPNQSGACSPATSSKASSSSHHKDKPLPVPPTLRDLPPPPPPDRPHSIASESRPQRRPLPSTPAEKPLLLPTNRPGETWHPRAVPKAPATNLTPGDPWTGGRELTNRHSLPFTLPSHIDERRDRHGSTQSLDNTGISATTELFGGLDNDDAKMKPSSSANAIYSLATRPFPVPPVGDHVDSGDESEYMCPSSRPLIPAPVAKTEARRPLETVPSLWPPDQQTERESYETMYNIQCQATTPVVVEPSREGAETNSAIANNGPEDDDNEDDGYDIPKPHLPMAIARRTLSDAPNATPAFCPGTISRDSGAGLPESSQVPERPPKPFPRRMNSERRPVVGGGFGDAPPAPLSSEIESLLSQGYSQQDVNKALLIARNNIEMARNILREFVAIPSPAHVAT

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny

Expression		tropicalis	laevis
UniGene		Str.1437	Xl.7228
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	CBL
mouse		MGI	Cbl	All(9) Targeted, knock Out(3) Targeted, other(6)
zebrafish		ZFIN ZFIN	cbl cblb	1 Lines(s) 3 Lines(s)

Publications
First:		Functional expression of transcobalamin II cDNA in Xenopus laevis oocytes. [Biochem Biophys Res Commun 1991]
Most recent:		Calcineurin B-like protein CBL10 directly interacts with AKT1 and modulates K(+) homeostasis in Arabidopsis. [Plant J 2013]
		View All Papers

Functional Ontologies
GO: Molecular:
Biological:
Cellular Component:
EC:
KOG:

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.1437.1.S1_at	Xl.7228.1.S1_at
Affymetrix 2.0			Xl2.7228.1.S1_at

Symbol legend[+]

- Blast this sequence
   - Literature Or Expression Images