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Summary Expression Gene Literature (361) GO Terms (21) Nucleotides (242) Proteins (37) Interactants (669) Wiki
XB-GENEPAGE-6456076
Gene Symbol:
aplnr

Gene Name:
apelin receptor

Synonyms:
apj , apjr , hg11 , X-msr , msr , Xmsr , angio1 , Xangio1 , agtrl1 , aplnr-a , aplnr-b ( Add synonyms , Nomenclature history )

Gene Function:
G-protein coupled receptor

Protein Function :
Receptor for apelin receptor early endogenous ligand (apela) and apelin (apln) hormones coupled to G proteins that inhibit adenylate cyclase activity (PubMed:17412318). Plays a key role in early develo...[+]


InterPro :
GPCR Rhodpsn 7TM , ATII rcpt , GPCR Rhodpsn

Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-6456077 XB-GENE-6254056 XB-GENE-6255483
Gene Symbol aplnr aplnr.L aplnr.S
Chromosome Chr1 chr1L chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 613084
399306
379537
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine aplnr aplnr.L aplnr.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards APLNR OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Aplnr MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Aplnr Ensembl
zebrafish
chicken
GEISHA APLNR Ensembl
fruit fly
worm
Publications
First Expression of a new G protein-coupled receptor X-msr is associated with an endothelial lineage in Xenopus laevis., Mech Dev 1996          
Most Recent The secreted BMP antagonist ERFE is required for the development of a functional circulatory system in Xenopus., Dev Biol 2020  
All View All Papers 26 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 17 terms 17 terms 16 terms
PANTHER aplnr
KEGG Pathways K04174 K04174 K04174
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks aplnr
Morpholinos aplnr MO1 , aplnr MO2 , aplnr MO3 , aplnr MO4 aplnr MO1 , aplnr MO2 , aplnr MO3 , aplnr MO4 aplnr MO1 , aplnr MO2 , aplnr MO3 , aplnr MO4
ORFs aplnr ORF1 aplnr.L ORF1 aplnr.S ORF1 , aplnr.S ORF2
Clones EXRC Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list