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XB-GENEPAGE-6462751
Gene Symbol:
ago3
Gene Name: argonaute 3, RISC catalytic component
Synonyms:
Argonaute3
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argonaute 3
( Gene Function: Translation initiation factor 2C (eIF-2C) and related proteins Protein Function
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Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and d...[+]
Interactants:
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Diseases: External Links:
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Xenbase Gene ID | XB-GENE-6462752 | XB-GENE-17336810 | XB-GENE-6488275 | |||||
Gene Symbol | ago3 | ago3.L | ago3.S | Chromosome | Chr2 | chr2L | chr2S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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Version 9.1
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CDS |
Gene model
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Entrez Gene |
100486574
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mRNA |
NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | ago3 | ago3.L | ago3.S | |||||
Orthology |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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worm |
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Publications | ||||||||
First |
Arginine methylation of Piwi proteins catalysed by dPRMT5 is required for Ago3 and Aub stability., Nat Cell Biol 2009 ![]() |
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Most Recent |
Expression of Alternative Ago2 Isoform Associated with Loss of microRNA-Driven Translational Repression in Mouse Oocytes., Curr Biol 2018 ![]() |
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All | View All Papers | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 11 terms | 0 term | 0 term | |||||
PANTHER | ago3 | |||||||
KEGG Pathways | ||||||||
KOG |
[J] Translation initiation factor 2C (eIF-2C) and related proteins
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | ago3 | |||||||
Clones | Horizon | |||||||
Plasmids | Addgene | Addgene |
Symbol legend:



