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Summary Expression Gene Literature (32) GO Terms (6) Nucleotides (104) Proteins (26) Interactants (369) Wiki
XB-GENEPAGE- 855943

Gene Symbol: h2afx

Gene Name: H2A histone family member X

Synonyms: h2ax , h2a/x , h2a.x
Add Xenopus synonyms , Nomenclature history


Gene Function: chromatin structure

Protein Function:
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central ro...[+]


Interactants: YYY

OMIM Disease Associations:
 
Xenbase Gene ID XB-GENE-855944 XB-GENE-6493983 XB-GENE-17331618
Gene Symbol h2afx h2afx.L h2afx.S
Chromosome scaffold_7 Scaffold82179
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq TrEMBL Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v7.1 gene model
GBrowse
laevis genome v7.2 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.27366 [+] Xl.19141 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 1 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine h2afx h2afx.L h2afx.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards H2AFX OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI H2afx MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN h2afx ZFIN Ensembl
chicken
GEISHA H2AFX Ensembl
fruit fly
worm
WORMBASE
Publications
First: Occurrence of H1 subtypes specific to pronuclei and cleavage-stage cell nuclei of anuran amphibians. [Dev Biol 1991]
Most recent: CRN13 candidate effectors from plant and animal eukaryotic pathogens are DNA-binding proteins which trigger host DNA damage response. [New Phytol 2016]
View All Papers 2 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 5 terms 4 terms 0 term
EC
PANTHER h2afx
KEGG Pathways K11251 K11251
KOG [B] Histone 2A
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Antibody H2afx , Hist1h4a Ab4 H2afx , Hist1h4a Ab4
ORF h2afx ORF1
Affymetrix 1.0 Str.27366.1.S1_at Xl.19141.1.S1_x_at [+]
Affymetrix 2.0 Xl2.19141.1.S1_at [+]

Symbol legend[+]

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