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Summary Expression Gene Literature (32) GO Terms (14) Nucleotides (81) Proteins (41) Interactants (235) Wiki
XB-GENEPAGE-852568
Gene Symbol:
dmrt1

Gene Name:
doublesex and mab-3 related transcription factor 1

Synonyms:
xdmrt1 , dmt1 , dmrt1-a , dmrt1-b ( Add synonyms , Nomenclature history )

Gene Function:
transcription factor

Protein Function :
Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and germ cell proliferation. Acts both as a transcription repressor and activa...[+]



Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-852569 XB-GENE-864801 XB-GENE-6255833
Gene Symbol dmrt1 dmrt1.L dmrt1.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100488257
735040
100048915
mRNA NCBI Nucleotide RefSeq RefSeq
Protein NCBI Protein RefSeq Swiss-Prot Swiss-Prot RefSeq Swiss-Prot Swiss-Prot Swiss-Prot
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine dmrt1 dmrt1.L dmrt1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards DMRT1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Dmrt1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Dmrt1 Ensembl
zebrafish
ZFIN, AGR dmrt1 ZFIN Ensembl
chicken
GEISHA DMRT1 Ensembl
fruit fly
worm
Publications
First The iron transporter DMT1., Int J Biochem Cell Biol 1999  
Most Recent Transcriptomic analysis identifies early cellular and molecular events by which estrogen disrupts testis differentiation and causes feminization in Xenopus laevis., Aquat Toxicol 2020  
All View All Papers 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 8 terms 11 terms 7 terms
PANTHER dmrt1
KEGG Pathways K19488 K19488
KOG [K] Transcription factor Doublesex
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks dmrt1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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Version: 4.14.0
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