ppm1a Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (3)

Nucleotides (374)

Interactants (5)

XB-GENEPAGE-852653

Gene Symbol: ppm1a Gene Name: protein phosphatase, Mg2+/Mn2+ dependent, 1A Synonyms: pp2ca, pp2calpha, pp2c-alpha Add Xenopus synonyms Gene Function: serine/threonine protein phosphatase Interactants: rpn1(2) , abi1(1) , akt1(1) , cbl(1) , ppp3ca(1) , View All

XB-GENE-852654

XB-GENE-852658

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001016158\|Xenopus (Silurana) tropicalis protein phosphatase, Mg2+/Mn2+ dependent, 1A (ppm1a), mRNA CAAAAGAGGAGGAGGAGGTGGGGGAGTAGAGAGCTCAATCCCTCGTTCCCTCGGCCGCCCCAGCCTCCGCGTTTCTTTATATCCCCCTCTCATTCATACATTTTCCCCGTCTAGCGCAATTACTCTCATATCCGCCGCCTTCTGCTCTGTCCTTTCTTCTCGGTTCCTCCGGTTTGGGGGAGGGGGCAGGTAGATAAGAGGAATGAGTCGTCGGTCAGCCCGGGGCTGAGAGACGCTCCCTGTCACCGTCTGAATGCTCTGAAGAGGGGGGGCAACAGCCTCTCCTCATTGGCAGCCTCCGCACCCAGTCCAGCCGGAATAAAAAATTAATACACAATGGGAGCATTTTTAGACAAGCCAAAGATGGAGAAGCATAATGCTCATGGGCAGGGTAATGGACTGCGATATGGGCTTAGTAGTATGCAAGGTTGGCGTGTTGAAATGGAAGATGCTCATACTGCTGTTATTGGGCTGCCAAATGGACTTGATGCATGGTCATTTTTTGCTGTTTATGATGGTCATGCGGGATCCCAGGTTGCCAAATACTGCTGTGAGCATTTGCTGGATCACATCACTAGCAACCAGGATTTCAAAGGGACAGATGGACATCTGTCTGTGTGGAGTGTAAAAAATGGAATCAGAACAGGATTTCTCCAGATTGACGAACATATGAGGGTAATCTCAGAGAAGAAACATGGTGCTGACAGAAGTGGATCAACGGCTGTTGGGGTTATGACCTCCCCAAACCACATTTACTTCATCAACTGTGGAGACTCCAGAGGTTTACTTTGCAGGAGCAAGAAAGTGCATTTCTTTACACAGGATCATAAACCAAGCAATCCACTTGAAAAGGAGCGTATACAAAACGCTGGGGGCTCTGTGATGATTCAGCGTGTAAATGGGTCACTTGCTGTTTCAAGGGCTCTGGGTGACTTTGATTACAAATGTGTCCATGGAAAAGGCCCTACAGAGCAGCTTGTTTCACCTGAGCCTGAAGTTTATGAAATTGAGCGTTCAGAAGAAGATGACCAGTTTATAATTTTGGCATGTGATGGTATTTGGGATGTCATGGGGAACGAAGAGCTATGTGATTTTGTGTGGTCAAGACTTGAAGTTACTGATGACCTTGAAAGGGTGTGCAATGAAATAGTGGACACCTGCTTGTACAAGGGAAGCAGAGACAACATGAGTGTCATACTGATCTGTTTTCCAAGTGCTCCAAAAGTATTGCCTGAGGCAGTGAAAAGGGAGGCGGAACTGGACAAGTACCTGGAAGGCAGAGTAGAAGACATCATAAAGAAGCAGGGTGAAGAAGGGGTACCAGACTTAGTCCATGTGATGCGTACATTAGCCTCTGAGAACATCCCTAATCTCCCACCTGGTGGAGAATTGGCAAGCAAACGGAGTGTGATTGAAGCTGTGTACAACAGATTGAATCCATATAGAAATGATGACACTGATTCGGCATCAACAGATGATATGTGGTAAATCTGTTCATATAGCTATGGAGTTTACACTCATCCTCTGAATGAACATACAACCCAACCTCAGTGATCCTTCTTAGCGTCCAACCATAACCTTGCCATTTAAAGAAGGGAATGTGATGTGGGTGAGAGTGATGATGACACAGATTATTATCATCCCCAAAGTACAAGAACTATCCCAATAATTCTTTGTTTTCATATTTATCCCCATCTCCTCCTCACAGGCTTTTGTAAAATCTGTTTTTCTGTACACTTAATTCAGACAAGAATTCACCATGTAAATCAGATTCCAGCAATTTTTTTGTTGTATGATTTTTGTTTATGTAAAGTGCAATTGTCCTTGTATAAAGTGGTCGTATTTAATTATGGACTGCAAATTGCTCTAAAGGTTACAGGAAGTCTGGCTTGTTTGTGGCGCCACCACTTATCTAACCCTATACATATATGTGATGGTTTTAGATGGAAAAGGAAGCAGCAACATAACCAGCTGGATTCCCATGATCTTGTTCATAATATAGTAACATAGTGAATATTACTCGCCTGCCATTCTATCATAATGAATGTTCAAACCTTCTGCGGTTCAATTCAGTGCTAAAGGGGCCCTTAGCCAATCACATTGAGTTAAATGCCTCTGCTGCCTTAGAGCTTACACACATTCTTGTGGTTCTGATAAGCAAGTAAGAGTGCTACGGTCATTTAAGAACAAAGTGTACCCATGAATAAGGTGACACACTCTATTTACTAATCATTTGTGTGCGGGGAGAGGGAGGGGGCTGTTTTCATTTTTTAAACTACACTGACTGGGTCTGTTAGCTGGATCTGTTGCTGCTACAGAGTTTTCAATTACATTTTATCAATAAAGCTTGATTTGACTAATAAATATGTTCACAAAAAAGTAATTTCTCATTTCTGTCCTTTGAGACCATGCCATTAGGAATGGGGGGTATCCATTAACCTAGATTTGCTGTTTTCAGCTGTATCCAGTGCCTGCTGCAAAGCTGACAGCCTAACTCTATGGCTAATGTGTGTATTTCTCCTGACCACTTTCTTCTTTTAAATAATGAGATTTGCTGAAGATTTGTTCATTTATTCATTCGTTTAGAATTGTAGTATGTTACAGAAAACCTTTTTAATTTCTGGCTCTTTGGAATTAAATATAAAATTCTGCATATGGAAAGTGACAACCTTGCCATGTTTTCCCCATCCTTTTCTTTTATTATTTTTATTGTCTTCACTGTAAAGGTGCGGTGAATTCAGTCATGTTTGTCCCCTTGTTTATTTCAGTATGTGTGGCCCCTATGAAGCTTTGCAAGTTCTCTTTTGCTTTGTGTCCCAGGATCTGATAACACACGTATAGATGTGCAAGTCTGACCCAGTCAGTCTGAGCTGTGTACACTGAACATAATTGACATGGCTTACAAGTGTGTTTTATTCAGGTTGCTTCCTCATCTTCCAAAACATTCAAAAGGGAAGATAAATGATTCCACCTCTCCCTAAGGGGCGCTTAAGCATTTCCCTGTGACACCCAGAGTCTGTCACTTCTTTTATCTGCACTCCCATTAATAATGGCATTTAAACAGGAAGCCTGCCACAGGTTTTCTGCTCACCACTGTTTGTTATAGGGATCATTCTGTATCATTTGTATGTCCTCCCAACCCCAAGTGAGGAAATACTCAAGTCCAGCAACTCACACTTAATGTCAATTCTGAGCAGTGCTAGAAGGTAACTATATTTCTGTTGCAGGTTCCCAGTACATTAAATAGAAAGCTTTCTGGACCACTGTATGAAAGATTATTTGTATGAATTTTTCACAAATTTAAATTATGATTAAAAAACAAAGTTGGGCTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001086897\|Xenopus laevis protein phosphatase, Mg2+/Mn2+ dependent, 1A (ppm1a), mRNA CCCATCTCATTCATACATTTTCCCCGTCTAGCGTCATTCATTTCCTATCCGCCGCTTTTCTCCTCGGTTCCTCCGGTCTGGAGGAAGGGGTAGGTAGATCAGAGGAATGAGTCGTCGGTCAGCCCGGGGCTCAGAGACGCTCCCTGTCACCGTGTGAATGATCTGAAGAGGGGCGGCAAGAGCCTCTCATTAGCGGCAGCCTCGCACCCAGTCCAGCCGGAGTAAAGAATTGATACACAATGGGAGCATTTTTAGATAAGCCAAAGATGGAGAAGCATAATGCTCATGGGCAGGGCAATGAACTGCGGTATGGGCTTAGTAGCATGCAAGGTTGGCGCGTTGAAATGGAAGATGCCCATACAGCTGCTATTGGGCTACCAAATGGACTTGATGCATGGTCATTTTTTGCGGTCTATGACGGACACGCTGGATCCCAGGTTGCCAAGTACTGCTGTGAGCATTTGCTGGATCACATCACAAGCAACCAGGATTTCAAAGGGACAGATGGACATCTGTCTGTGTGGAGTGTAAAAAATGGAATCAGAACCGGATTTCTCCAGATTGATGAACATATGAGGGTAATCTCCGAGAAGAAACATGGCGCCGACAGAAGTGGATCGACGGCTGTTGGGGTGATGCTCTCCCCAAATCACATTTACTTTATCAACTGTGGAGACTCCAGAGGTTTACTTTGCAGGAGCAAGAAAGTGCATTTCTTTACACAGGATCATAAACCAAGCAATCCTCTCGAAAAGGAGCGCATACAAAATGCCGGGGGCTCTGTGATGATTCAACGTGTAAACGGGTCGCTTGCTGTTTCAAGGGCTCTGGGTGACTTTGACTACAAATGTGTCCATGGAAAAGGCCCTACGGAGCAGCTTGTTTCGCCTGAGCCTGAAGTTTATGAAATTGAGCGTTCAGAAGAAGATGACCAGTTTATCATTTTGGCATGTGATGGTATTTGGGATGTCATGGGAAACGAAGAGCTGTGTGATTTTGTGGGGTCAAGACTTGAAGTTACTGATGACCTTGAAAGGGTGTGCAATGAAATAGTGGACACCTGCCTGTACAAGGGAAGCAGAGACAACATGAGTGTCATACTGATCTGTTTTCCAAGTGCTCCAAAAGTATTGCCCGAGGCAGTGAAAAGGGAGGCGGAACTGGACAAGTACCTGGAAGGCAGAGTAGAAGACATCATAAAGAAGCAGGGTGAAGAAGGTGTACCAGACTTAGTCCATGTGATGCGCACATTAGCCTCCGAGAACATCCCTCATCTCCCACCTGGGGGCGAATTGGCCAGCAAACGGAGTGTGATTGAAGCAGTGTACAACAGATTGAATCCATATAGAAATGATGACACTGATTCTGCATCAACAGATGATATGTGGTAAATCTGTTCCTATAACTATGGAGTTTACACTCATCCTCCGAAAGAACCTACAACCCAACCTCAGTGATCCTTCTTAGCGTCCAACCATAACCTTGCCATTTACAGAAGGGAATGTGATGTGGGTGAGAGTGATGATACAGATTATCCCAATAATTTGTTTTCCTGTTTATCCCCCATCTCCTCCCCACAGGCTTTTTTTTGTAAAATTTCTGTACCTTTAATTCAAACAAGAATTCAACATGTAAATCAGACTCCAGCAAAAAATTTTTTTTTTTTTGTTGTATGATTTTTGTTTTTGTAAAGTGCAATTGTCCTTGTATAAAGTGGTCGTATTTAATTATGGACTGCAAATTGCTCTAAAGGTAACAGGAGGTCTGGCTTGTTTGTGACACCACCACTTATCTAACCCTATACATATATGTGATGGTTTTAGATGGAAAAGGAAGCAGCAACATAACCAGCTGGATTCCCATGATCTTGTTAATAATATTGTAATGTTAGTGAATATTACTAGCCTGCCATTCTTATCATAATGAATGTTGAACTTTCTGTGGTTAAATTCTATGCTGAAGGGGCCCTTAGCCAATCACGTTGAGTTAAATGCCTCCGCCGCCTTAGAGCTTAAACGCATTCCTTGGGTTTTCGAAAAGCAATTCTGAGAATGAAGACGAAAGGGGAACTAATCGTTTTGCGTGCAGAGAGGGAGAATAATGGGGAAACTTATTTTTAAAATTCCACTGGCTGGGTCTGTTGCTGCTACAGAGTCTTCAATTACATTTTATCAATAAAGCTTGATTTGACTAATAAATATATTCACAAAGGAGTAATTTCTCACTCTGTCCTTGGAGACCGCGCCAGTAGGAGAGGACGTAGAGTGTCAGCTCTGCAGCAGCTGCAAACAGTAACACTTGGGCTAATGTGTGTATTTCTCCTGACCACTTTTCTTTTTTTAAACAATGATAAACTTGCTTGAATATTTGTCAATTCAGAATTGTAGCATGTTACAGGACAAAAAGATTTAATTTCTGGATATTTGGAATTAAATATAGAATTCTGCATATGAAAAAAAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001016158\|protein phosphatase 1A [Xenopus (Silurana) tropicalis] MGAFLDKPKMEKHNAHGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPNGLDAWSFFAVYDGHAGSQVAKYCCEHLLDHITSNQDFKGTDGHLSVWSVKNGIRTGFLQIDEHMRVISEKKHGADRSGSTAVGVMTSPNHIYFINCGDSRGLLCRSKKVHFFTQDHKPSNPLEKERIQNAGGSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVYEIERSEEDDQFIILACDGIWDVMGNEELCDFVWSRLEVTDDLERVCNEIVDTCLYKGSRDNMSVILICFPSAPKVLPEAVKREAELDKYLEGRVEDIIKKQGEEGVPDLVHVMRTLASENIPNLPPGGELASKRSVIEAVYNRLNPYRNDDTDSASTDDMW	Refseq >NP_001080366\|protein phosphatase 1A [Xenopus laevis] MGAFLDKPKMEKHNAHGQGNELRYGLSSMQGWRVEMEDAHTAAIGLPNGLDAWSFFAVYDGHAGSQVAKYCCEHLLDHITSNQDFKGTDGHLSVWSVKNGIRTGFLQIDEHMRVISEKKHGADRSGSTAVGVMLSPNHIYFINCGDSRGLLCRSKKVHFFTQDHKPSNPLEKERIQNAGGSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVYEIERSEEDDQFIILACDGIWDVMGNEELCDFVGSRLEVTDDLERVCNEIVDTCLYKGSRDNMSVILICFPSAPKVLPEAVKREAELDKYLEGRVEDIIKKQGEEGVPDLVHVMRTLASENIPHLPPGGELASKRSVIEAVYNRLNPYRNDDTDSASTDDMW

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.7047 [+] Str.63212 Str.41500	Xl.7338 [+] Xl.29723 Xl.72140
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	PPM1A
mouse		MGI	Ppm1a	All(4) Targeted, other(2)
zebrafish		ZFIN	ppm1bb	1 Lines(s)

Publications
First:		A protein kinase-phosphatase pair interacts with an ion channel to regulate ABA signaling in plant guard cells. [Proc Natl Acad Sci U S A 2009]
Most recent:		Reconstitution of abscisic acid activation of SLAC1 anion channel by CPK6 and OST1 kinases and branched ABI1 PP2C phosphatase action. [Proc Natl Acad Sci U S A 2012]
		View All Papers

Functional Ontologies
GO: Molecular:		CTD phosphatase activity calcium-dependent protein serine/threonine phosphatase activity calcium-dependent protein serine/threonine phosphatase regulator activity More[+] catalytic activity magnesium-dependent protein serine/threonine phosphatase activity myosin phosphatase activity myosin phosphatase regulator activity phosphoprotein phosphatase activity protein phosphatase type 2A activity protein phosphatase type 2B activity protein phosphatase type 2C activity protein serine/threonine phosphatase activity
Biological:		protein amino acid dephosphorylation
Cellular Component:		magnesium-dependent protein serine/threonine phosphatase complex myosin phosphatase complex protein serine/threonine phosphatase complex
EC:		phosphoprotein phosphatase
KOG:		[T] Protein phosphatase 1B (formerly 2C)

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.7047.1.S1_at [+] Str.41500.1.A1_x_at Str.41500.1.A1_at Str.7047.1.S2_at Str.7047.2.A2_at Str.7047.2.A1_at	Xl.12288.1.A1_at [+] Xl.7338.1.S1_at
Affymetrix 2.0			Xl2.7338.1.S1_at [+] Xl2.12288.1.A1_at

Symbol legend[+]