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Summary Expression Gene Literature (2) GO Terms (7) Nucleotides (136) Proteins (20) Interactants (238) Wiki
XB-GENEPAGE- 852756

Gene Symbol: kmt5b

Gene Name: lysine methyltransferase 5B

Synonyms: cgi85 , cgi-85 , suv4-20 h1 , SUV420H1
Add Xenopus synonyms , Nomenclature history


Gene Function: histone tail methylase

Protein Function:
Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in per...[+]


Interactants: YYY

OMIM Disease Associations:
1/3
 
Xenbase Gene ID XB-GENE-852757 XB-GENE-6253211 XB-GENE-866439
Gene Symbol kmt5b kmt5b.L kmt5b.S
Chromosome scaffold_4 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq Refseq
Protein NCBI Protein Refseq Swiss-Prot TrEMBL Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v7.1 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.35069 [+] Xl.71915 Xl.1754
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 11 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine kmt5b kmt5b.L kmt5b.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen ttpa011k01      
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards KMT5B OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Kmt5b MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN kmt5b ZFIN Ensembl
chicken
GEISHA KMT5B Ensembl
fruit fly
worm
WORMBASE
Publications
First: Defining synphenotype groups in Xenopus tropicalis by use of antisense morpholino oligonucleotides. [PLoS Genet 2006]
Most recent: Suv4-20h histone methyltransferases promote neuroectodermal differentiation by silencing the pluripotency-associated Oct-25 gene. [PLoS Genet 2013]
View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 0 term 7 terms 7 terms
EC
PANTHER kmt5b
KEGG Pathways K11429 K11429
KOG [B] Histone tail methylase
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Morpholino suv420h1 MO1 , suv420h1 MO2 , suv420h1 MO3 suv420h1 MO1 , suv420h1 MO2 , suv420h1 MO3 suv420h1 MO1 , suv420h1 MO2 , suv420h1 MO3
ORF suv420h1 ORF2 suv420h1 ORF1
Affymetrix 1.0 Str.16943.1.S1_at [+] Xl.24465.1.S1_at Xl.1754.1.S1_at
Affymetrix 2.0 Xl2.44518.1.S1_at Xl2.1754.1.S1_at

Symbol legend[+]

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