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Summary Expression Gene Literature (28) GO Terms (13) Nucleotides (125) Proteins (41) Interactants (346) Wiki
XB-GENEPAGE- 852890

Gene Symbol: dlx2

Gene Name: distal-less homeobox 2

Synonyms: X-dll4 , tes1 , tes-1 , Xdll4
Add Xenopus synonyms , Nomenclature history


Gene Function: homeodomain and LIM zinc binding domain transcription factor

Protein Function:
Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sproutin...[+]


Interactants: Loading ...

OMIM Disease Associations:
1/3
 
Xenbase Gene ID XB-GENE-852891 XB-GENE-852896 XB-GENE-17342444
Gene Symbol dlx2 dlx2.L dlx2.S
Chromosome Chr09 chr9_10L chr9_10S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq TrEMBL Refseq Swiss-Prot TrEMBL Refseq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.9796 Xl.721
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 69 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine dlx2 dlx2.L dlx2.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards DLX2 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Dlx2 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN ZFIN dlx2a dlx2b ZFIN Ensembl
chicken
GEISHA DLX2 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Xenopus Distal-less related homeobox genes are expressed in the developing forebrain and are induced by planar signals. [Development 1993]
Most recent: A molecular atlas of the developing ectoderm defines neural, neural crest, placode, and nonneural progenitor identity in vertebrates. [PLoS Biol 2017]
View All Papers 7 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 9 terms 7 terms 3 terms
EC
PANTHER dlx2
KEGG Pathways K18488 K18488 K18488
KOG [K] Transcription factor DLX and related proteins with LIM Zn-binding and HOX domains
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Antibody Dlx2 Ab1 Dlx2 Ab1
ORF MGC80142 ORF1
Affymetrix 1.0 Str.9796.1.S1_at Xl.721.1.S1_at
Affymetrix 2.0 Xl2.721.1.S1_at Xl2.10415.1.S1_at

Symbol legend[+]

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