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Summary Expression Gene Literature (174) GO Terms (23) Nucleotides (319) Proteins (36) Interactants (528) Wiki
XB-GENEPAGE- 853081

Gene Symbol: aurka

Gene Name: aurora kinase A

Synonyms: Aurora-A , btak , stk15 , Aurora A , aik , ark1 , aura , stk6 , stk7 , aurora2 , pEg2 , Eg2 , aur-a
Add Xenopus synonyms , Nomenclature history


Gene Function: serine/threonine kinase

Protein Function:
Mitotic serine/threonine kinases that contributes to the regulation of cell cycle progression. Associates with the centrosome and the spindle microtubules during mitosis and plays a critical role in va...[+]


Interactants: YYY

OMIM Disease Associations: COLORECTAL CANCER; CRC
 
Xenbase Gene ID XB-GENE-853082 XB-GENE-866460 XB-GENE-17337404
Gene Symbol aurka aurka.L aurka.S
Chromosome scaffold_10 chr9_10L chr9_10S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq TrEMBL Refseq Swiss-Prot TrEMBL Refseq Swiss-Prot Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v7.1 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.25531 Xl.124 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 14 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine aurka aurka.L aurka.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tegg021k02      
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards AURKA OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Aurka MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN aurka ZFIN Ensembl
chicken
GEISHA AURKA Ensembl
fruit fly
worm
WORMBASE
Publications
First: Degradation of a developmentally regulated mRNA in Xenopus embryos is controlled by the 3'' region and requires the translation of another maternal mRNA. [Mol Cell Biol 1991]
Most recent: Chromosomal passenger complex hydrodynamics suggests chaperoning of the inactive state by nucleoplasmin/nucleophosmin. [Mol Biol Cell 2017]
View All Papers 3 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 12 terms 15 terms 16 terms
EC
PANTHER aurka
KEGG Pathways K11481 K11481 K11481
KOG [D] Serine/threonine protein kinase
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Antibody Aurka Ab1 , Aurka Ab2 , Aurka Ab3 , Aurka Ab4 Aurka Ab1 , Aurka Ab2 , Aurka Ab3 , Aurka Ab4
Morpholino aurka MO1 aurka MO1 aurka MO1
ORF aurka ORF1
Affymetrix 1.0 Str.25531.1.S1_at [+] Xl.124.1.S1_at Xl.4421.1.S1_at
Affymetrix 2.0 Xl2.124.1.S1_at Xl2.4421.1.S1_at

Symbol legend[+]

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