aurka Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (134)

Interactants (93)

XB-GENEPAGE-853081

Gene Symbol: aurka Gene Name: aurora kinase A Synonyms: Aurora-A, btak, stk15, Aurora A, aik, ark1, aura, stk6, stk7, aurora2, pEg2, Eg2 Add Xenopus synonyms Gene Function: serine/threonine kinase Interactants: tpx2(25) , aurkb(24) , cdk1(16) , ccnb1.2(11) , ran(10) , mos(9) , pold1(9) View All

XB-GENE-853082

XB-GENE-866460

Molecules		tropicalis	laevis
Gene		JGI XT Genome 4.1 Ensembl
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001016570\|Xenopus (Silurana) tropicalis aurora kinase A (aurka), mRNA CAATCCGGTCTGTGTGAGAGCTGCTAGAGTCCCGGCCCGCACATTCGGCTGCCAGGCACATATAATGGAACGGGCTGTTAAAGAGAATCTTCCTTCTAATGTCAAGGTTTTCCACCCCACAATGGAGGGTCCCAAACGTATCCCAGTTACCCAGCCTCCGAGCACCCAGGTTAGACCTCCTGGGACTGCCGTCTCTGCCCAGAGGATATTGGGTCCCTCCAATGTGCCACAGCGAGTCGTGTCTCAGGCTCAGAAACCTGTTATGTCCGCTCAGAAACCTGTTATGTCCACTCAGAAGCCAATGACTCAGGGGCCACTGAGGCCAGTAACTCATGGGCATCAGGCTGGCAAACCACAGGGACCAAATGAGAATCGTACTCCACAGCAGACCAGCCATTCCTCCACTCCAAACGTGGAGAAGAAAGGAAGCACCGATCAAGGAAAGACTCTGGCTGTTCCCAAAGAGGAGGGCAAAAAGAAACAGTGGTGCCTGGAAGACTTTGAGATTGGGCGCCCCCTGGGCAAAGGGAAGTTTGGGAACGTGTATCTGGCGCGCGAGCGGGAGAGTAAATTCATCCTGGCGCTGAAAGTCCTGTTTAAAACTCAGCTGGAGAAGGCAGGGGTAGAGCACCAACTGCGGAGGGAGGTGGAAATTCAGTCCCATCTCAGGCATCCAAACATCCTCCGGCTATATGGGTACTTCCATGATGCCGCCCGAGTCTACCTAATCCTGGATTATGCCCCCGGCGGGGAGCTGTTCCGAGAGCTGCAGAAAGTCACCAGATTTGATGAGCAGAAGAGCGCCTTGTACATCAAACAGCTGGCAGAAGCCCTCCTGTACTGTCACTCCAAGAACGTGATACACCGGGATATCAAGCCAGAGAACTTGCTGCTCGGTGCCAACGGGGAACTGAAGATCGCTGACTTTGGTTGGTCTGTGCACGCGCCGTCCTCCAGGAGGACCACTCTGTGCGGAACCCTGGACTATCTCCCTCCTGAGATGATTGAGGGCCGAATGCACGACGAGAAGGTGGACTTGTGGAGCCTGGGAGTCCTCTGTTATGAGTTCCTTGTAGGGAAACCTCCATTTGAGACTGACACCCACCAGGAAACCTACAGACGTATTTCAAAGGTTGAATTTCAGTATCCTTCGTATGTATCGGAAGGAGCCAGAGATCTCGTATCGAAGCTGTTAAAGCACAACCCAAACCACAGGCTGTCCCTGAAGGGGGTTCTCGAACATCCGTGGATCATAGATAATTCTGCTCAAAAGCCCAAGAGGAAAGAGGGGCCGGTTACAGGGGCTCAATAGGAAATCCCCTGTGGATCTTTACTTTCCCAAATGTGAGAAGGCACAGCAATTTGCACCTGCTGGATACCCCCCTGCCCTGTTTAATGGGGGGGGGGGGGGGGTCACAATCTGGCAACTCACAGCTCAGTATTTGCTTATTGACTCCAACACAAGGCAATGTACCATGGAACACTCACCGCCTTGCGTGCCTTTTGTGAATGGGACTAGACTGCCTGATCTGGAACGACGGGTTCTTTAAAGGGGCCACGAGGCCCGGTGCTTTATAACTTCTATCGTCACAAACCACTGCTCTGCTACTGGCACAGGTTCCCTTTACTATGGATGTTTAACCCCAGATGCGGCAGTTATAAAACTGTATACGCACTGACAACTAAAATCTGCCGGTTCCGACACCACTGATTGATTATACAGAGATTGTAAGGTTTCCTTGGCCGGTGCAATAGTGATGTGAATGCCTTGGGTATATTTATTAGGCTGCTAATATGGCTGTCCCATTACACAGCTGCTCTGAATACTGAGAGAATGAATTCAGTGTAAATACCTATTCTGTATCAACTTATATCTCGTCTGTCCTTTTATGTGTTAACAACACTTTTTAGAAAAGCATAAAAATCTGTTCTAAGATGCTCCCTTTTCTTTCTGTGTTTTAAAATAAAGCTGATTGAAAAAGTTAAAAAAAAAAAAAAAAAAA	Refseq >NM_001088096\|Xenopus laevis aurora kinase A (aurka), mRNA CGGAGAAGGAAGGAAGTAAGTGGCTGAGCTGCTGGGGGGGAAGACAGAGGTGCGTTCCAGTCGTGTGGGAAGAGGGAGCCTCAGGTTTTTGCGTCTGCAGCTAACCTTGCCTTGCCTCGCCTCGCCTCGCCTCGAACCTAACTATCTGACAGTTGCTACAGACTCGGCCTGCACATTTAGCTGCCAGGCATTCATAATGGAGCGGGCTGTTAAGGAGAACCACAAGCCTTCTAATGTGAAGATTTTTCACCCCATGACTGAGGGAGCTAAACGTATCCCAGTTAACCAGCCGCAGAGCACTCAGTTTAGGCCTCCTGGGACTGCAGTCTCTGCCCAGAGGATATTGGGTCCCTCTAATGTGCCGCAGCGAGTGTTGGCTCAGGCTCAGAAACCTATTCTGTCCAGTCAGAAGCCAACGACTCAGATCCCCCTGCGGCCAGCAACTCAAGGGCATCAGTCCAGCAAACCACAGGGACCAAATGAGAATCGCAATCCACAGCAGACAAGCCATTCCTCCACTCCAAATGTGGAAAAGAAAGGAAGCACCGATCAAGGAAAAACTTCAGCTGTTCCCAAAGAGGAGGGCAAAAAGAAACAATGGTGCCTGGAAGACTTTGAAATAGGGCGGCCCCTGGGCAAAGGGAAGTTTGGAAATGTTTATCTGGCACGCGAGCGGGAGAGTAAATTCATCCTGGCGCTGAAAGTCCTGTTTAAATCCCAGCTAGAGAAGGCGGGCGTAGAGCACCAGCTACGGCGGGAGGTGGAAATTCAGTCCCATCTCAGGCACCCCAATATTCTCCGGCTCTATGGCTATTTCCACGATGCTTCCAGAGTCTACCTAATCCTGGATTATGCCCCTGGTGGGGAGTTGTTCAGAGAGCTGCAGAAATGCACAAGATTTGATGATCAGAGAAGTGCCATGTACATCAAACAGCTGGCAGAAGCCCTCCTGTACTGTCACTCCAAGAAGGTGATACACAGGGACATCAAGCCAGAGAACTTGCTGCTTGGCTCCAATGGAGAACTGAAGATCGCCGACTTTGGCTGGTCTGTGCATGCTCCATCCTCCAGGAGGACCACTCTGTGTGGAACACTGGACTATCTACCTCCTGAGATGATCGAGGGCAGAATGCATGATGAGACGGTGGACTTGTGGAGTCTGGGAGTTCTCTGTTACGAATTCCTCGTAGGGAAACCTCCGTTTGAGACTGACACCCACCAGGAAACCTACAGACGTATTTCAAAGGTTGAATTTCAATATCCGCCATATGTATCGGAAGAGGCAAGAGATCTTGTCTCAAAGCTGTTAAAGCACAACCCAAACCACAGGCTGCCACTGAAAGGGGTTCTCGAACATCCATGGATCATAAAAAATTCTCAACTCAAGAAGAAAGACGAGCCCCTTCCAGGCGCCCAATAGGAAATCTCCTGAGGCTCCGACTCTCTTCCCAAATGTGAGAAGGCATAACCGTTTGCACCTGCTAGATAACGCCTCTTATTTTTAATTGGGAGGTGGCTAATCCTTCCAAAAGTGAGGGGTGATCATGATCTGGCAACTCATTGCTCAGTATTTGCTTATTGACTCAAACACAAGGCAATGTACCACGGAACACTCAGTCTTATGTGGCTTCTGTGAAAAGGACTGATCTAGATTTGGAACAACGGGTTCTTGCAAGGCCTGGTGCTTAATTTCCACTGCTCTGCTGTTGGCACAGGTTCTCTTTATATCTTGAAGGATATTTTTACACAGACCCGGCAGTCTGTATATGCACTGAGAACTGTAAAATCTGCTATTTCCGACTGCTACAACAAGCAAGTTATTCTCTACTGAATGCTGTAATATACGGAGATTCTGAGGTGCAATAGCGATATGAATACCTGGGTATATTTATTAGGCTGCTAATATGGCTGTCACCGTACAACGCTACTTGAATACTGAGTGAATGAACGAATGTAAATACATATTCTGTATTAATTTCGTATGTCCTTTTATATGTAACACTTTTTAAAAAGGCAAAAAATCTGTTCTAAGATGTTCCTTTTTTTTTTTTTTCTTCTTCTGTTTAAATGTTTTAAAATAAAGCTTTGATTAAAAAGAAAAAAAAAAAAAA
Protein		Refseq >NP_001016570\|aurora kinase A [Xenopus (Silurana) tropicalis] MERAVKENLPSNVKVFHPTMEGPKRIPVTQPPSTQVRPPGTAVSAQRILGPSNVPQRVVSQAQKPVMSAQKPVMSTQKPMTQGPLRPVTHGHQAGKPQGPNENRTPQQTSHSSTPNVEKKGSTDQGKTLAVPKEEGKKKQWCLEDFEIGRPLGKGKFGNVYLARERESKFILALKVLFKTQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDAARVYLILDYAPGGELFRELQKVTRFDEQKSALYIKQLAEALLYCHSKNVIHRDIKPENLLLGANGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFETDTHQETYRRISKVEFQYPSYVSEGARDLVSKLLKHNPNHRLSLKGVLEHPWIIDNSAQKPKRKEGPVTGAQ	Refseq >NP_001081565\|serine/threonine-protein kinase 6 [Xenopus laevis] MERAVKENHKPSNVKIFHPMTEGAKRIPVNQPQSTQFRPPGTAVSAQRILGPSNVPQRVLAQAQKPILSSQKPTTQIPLRPATQGHQSSKPQGPNENRNPQQTSHSSTPNVEKKGSTDQGKTSAVPKEEGKKKQWCLEDFEIGRPLGKGKFGNVYLARERESKFILALKVLFKSQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSAMYIKQLAEALLYCHSKKVIHRDIKPENLLLGSNGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDETVDLWSLGVLCYEFLVGKPPFETDTHQETYRRISKVEFQYPPYVSEEARDLVSKLLKHNPNHRLPLKGVLEHPWIIKNSQLKKKDEPLPGAQ UniProtKB

Genomic

tropicalis

Genome Browser

Synteny

Xenbase G-Browse

GBrowse

Expression		tropicalis	laevis
UniGene		Str.25531	Xl.124
Gurdon EST/FL		ANHP475	IMAGE:6642394
Affymetrix 1.0		Str.25531.1.S1_at	Xl.124.1.S1_at
GEO data			GEO

Phenotype		tropicalis	laevis
Smith Morpholino Screen		tegg021k02

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene	AURKA	OMIM:114500
mouse		MGI	Aurka	All(5) Targeted, knock Out(1) Targeted, other(3) Gene Trapped(1)
zebrafish

Publications
First:		Degradation of a developmentally regulated mRNA in Xenopus embryos is controlled by the 3'' region and requires the translation of another maternal mRNA. [Mol Cell Biol 1991]
Most recent:		Defective membrane expression of the Na+-HCO3- cotransporter NBCe1 is associated with familial migraine. [Proc Natl Acad Sci U S A 2010]
		View All Papers

Functional Ontologies
GO: Molecular:		ATP binding protein kinase activity protein serine/threonine kinase activity More[+] protein tyrosine kinase activity
Biological:		protein amino acid phosphorylation
Cellular Component:
EC:
KOG:		[D] Serine/threonine protein kinase

Suppliers		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice	geneservice
		RZPD imagenes	RZPD imagenes

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