egr2 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (137)

Nucleotides (55)

Interactants (453)

XB-GENEPAGE-853289

Gene Symbol: egr2 Gene Name: early growth response 2 (Krox-20 homolog) Synonyms: XKr20, EGR-2, Krox-20, XKrox-20, krox20 Add Xenopus synonyms Gene Function: zinc finger transcription factor Interactants: en2(72) , otx2(66) , hoxb9(37) , chrd(33) , snai2(30) , sox2(30) , nog(27) View All	1/3

XB-GENE-853290

XB-GENE-866474

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001100255\|Xenopus (Silurana) tropicalis early growth response 2 (Krox-20 homolog) (egr2), mRNA CTGCTCTGCCAGGGACACTACAACTGCACTGGCACTCTCACTGCTGGAAGCAATGCCAACATGTGCCTGCTAAGCCTACCCTTGGGATGCAGCTAGAGACGCGCCTCAGAGCTGCCAGGGACATCTAAAGAGCTGTTTGTTCCCCCACTATAACAATAATAATAATAATTCAGATTTGCTTGAATTGACCCTGGGGGCACTCGGTGAGACCATGGCTGCCAAAGCGGTAGATAAACTCCCAGTGACTTTTGGTAGTTTTGTGCATCAGTTCCCAGAAGGCATCTACCCCGGGGAGGATTCCACCCTGCCTGCCTCTGTGACCATCTTCCCTAATGTGGACCTGGGGGGACCCTTTGATCAGATGAACAGTGTGACAGGAGATGGAATGATCAGTGTGGATATGAATAATGAGAAGCGATCGCTGGATTTCTCCTACTCGTCCAACTACCCCTCTGCCCCCCGCAGCCAGCCCTTAGCCTATATGGGCAAGTTCTCCTTTGACCCCCAGTACCCCGGGGCCGGCTGGAATACAGAGGGAATCTTCAATATAGTGAGTGCTGCTAGCATCCTGGGGGTGCCCCCCTCCTCATCTTCCTCCACCACCTCCTCTAACGCCTCATCGGGGTCCCCCAACCTGAGTTGCAGCATGGCTCACCCCCAGAGTGACATGGACCATATCTACTCACCTCCCCCCTACTCCAGCTGCAATGAGATCTACCAGGACCCCTCGGCTTTCATTGGCACCTCCACAGGGGCACCCTACCCGCCCCCTTCCTACCCTTCTCCTAAGGGGGCGTCGGATGGGAGCGTCTTCCCCATGATCCCGGACTACTCGGCTCTCTTCCCTCCCCAATGCCAAAGAGACTTGCACTCCATGCCCGATAGGAAACCCTTTCCGTGCCCCCTGGACTCAATCCGGGTCCCCCCACCTCTCACCCCCCTCTCCACCATCCGCAATTTCACATTGGGGGGCTCCAGCAATGAGGGGTCCAGGCTGCCCAGCGCTTACAGCCCCCATAACTTACCACTTCGACCCATCCTCAGACCCAGAAAATACCCCAACCGCCCCAGTAAGACCCCTGTCCACGAAAGACCTTATCCCTGCCCGGCAGAGGGCTGCGACAGACGCTTCTCGCGTTCTGACGAACTGACCAGACATATCCGAATTCACACTGGCCACAAACCCTTCCAGTGTCGCATCTGTATGAGAAACTTCAGCCGCAGCGACCACTTGACTACTCACATCCGGACGCACACCGGGGAGAAACCTTTCGCCTGCGACTACTGCGGGAGAAAGTTCGCCCGGAGCGATGAGCGCAAAAGGCACACAAAAATCCATCTGCGGCAGAAGGAGAGGAAAAACTCGGCAACAGCGGCACCTAGCGGCAGTGCGACCCAAGAGCGACCGCTGAGCCTGAGTCCCGCAGGGACCGGTAACAGTATGTGCTCCACTGGGTCAAGCAGCGGCCAATTGGGACTGTGCCCTAGCCGGACAGGGTGACACACGGACAGTGTAACCCCCACACAGGGATCAAGGGGTCCGTCACTCCCACAAGGATTCCCCAAGAAATCGCACAGCCAGACTTAGTGGCAGTTATCTTTATCCAGGCAATCACCTAGGATACAAACTGGAAACAACCTCCAGCATTAACACCTTTTGATGGGGGGGGTCTATGGTGGGCAAGTTACTGTCAAACGCTAAATAAATGCTTGGTGTTTAGTTCTGGCAGCAAAGTCGAGGTGTGTAAGTCAGAAGGGAGTTAGTGACAAGTCAGTGTAATGTCACCAATAGGAGCTTATATATATGCCAGGGAATGCTTGGGCACAAGTGCTGGGCATCTGTACCATTCATGCAGGGGCTGAGTTGTGGGTTATTAAGGATAAATTCTCTTAGCCCTGCAGAGTTTGCTTAACTACAGCTCCCATCATTTATCTATTGGGAAAAGCAGAGAAAAAGCTGAGCCCCTGTGCAGCCTCTGCAGTAGCAGCTACAGTCCAGCTAATGGCTGCACAAAGGACACATGGGAAACATTTAATTACAAATTTGCAGCAGGGCAGTAATCCAGCAACTAGCTGCAAATAACCCAGGGTTACAATAATGGGTTGCTATTGGTTACTACCTTGGTGCAATTTTGCAGCTGGTCTAGTAACTGAAGGCCAAAAATAATTTCCAGTGAGACATTGTGGTACTGTCCCTTTCCCTTTCTCTCCAAAGCCCCTATGAAAGGAGAATAGCTACATTATTTTATTGGTTCTCCTACTGCAAAAAGACAGTCACATGATAAATCTCTGCCGAAACAGTGCAAAGTCTTGGCAGGAATTTCTCATAGTCAATCCAATCACATTATATTGCACCATTTAATATAAGCAAGCCATTAAAGTGACAGTGGCTGAATTTTGGGAGCAAACACAGTATATTAGAGTGTCGCTGTCTCATCCTTCAGCAGAAAAGGGGGTGTCTGATAGTCCTGGGTGGCCTAATAGACCTGGGCGGGTTGAGCTCCACAGAGTCAAGTGCTGAATAATCAGGTTTGCCTTTTATTTCTTACTAACCGTGTGTCATTTTCATGCGTGATTCTTACTTTTTTGTAACTTTTTGGGGGCTAAATTCAGGGAAAAATGGAGATATGGTAACTTTGAAAGGTGTTTTCTATCCTTTCCCATCCTTGGGGTGAAGCACCTGTAGTAGCCATAGTTTTGTGCACTTTATAACTTCATGACTGCTCCGGAGAGGCGGCATGATATGAAGGGAGGATGTCTGGAATTTCTAAAGCCTACCCTAGATTTAATATTTTCATTTTTTTCCTAATTAATAACATTATTTTTTTTTTGGTGTAACCAATACAGTGTGACTAACAGGAGTGCATTCTAAAGGTACTGTTACGTTTGGCACTGCTGAGTTGTGTAGAACCCTTACATCTCTTTAGGGGACTATTTTATTTCTTTTCAGTGTAAGCCCTGCTGCTGTTGATGAACTACAGATCCCAGAATCCTTAGCTGGGCCTTGTAGTTCAACAACGTGGCAGCAGACATCCACCGACTGTCAATAATGTTGATCTGCACTGTTTTACAGAGTTCCAGACCTTTTTGGTTGGAGTGAAACAGGACTCTGTATGTAATATAGAAGCGCCAGAGAGCCTAATTTATTTAAGGATGTATATAGTTTGTGTACGACGTTAGATTGCATGCCTCTCTGCTACTCAGTGTTCATGGTGCCTTGTGTGATGTGGACAATTCTCGCCCTGTCTGCATGTATATATAGGTTGCCTTATCCACGACACAGCGGTGGCCCGGGGGCCACCGTTTAACATAGCTGTACATTACTGCCAATTAATATTTGGAATTTTTTCTAGAATTTCTATTTTTGTACCCAAACGCACTGTTTTGTGACCCAAAAGTGTTAACTTTGTAGTTGAGTTTACAAAAAAATACAAAATACGGGATAAAAAAATAAGGAAAAAAAAAAGAATATGGCATTGACGGGGCTGCTTCTGTACTCGGAAATAAAGTGTTAAAGAGTTTACTTTATTAATAACCAGCCACTAACTGGAATGGAATCATGAAATGTACTTAGATACAAAGACTGTAAATAAATACTTTTCAACTATAAAAAAAAAAAAAAA	Refseq >NM_001085779\|Xenopus laevis early growth response 2 (Krox-20 homolog) (egr2), mRNA GCTCACAGCTGCCAAGGACATCTAAGGAGCTATTTATTCTCTCTCCCAATAATAATAATAATAATTCCTGTTGGGTTGAATTGACCCTGGGGGGGCACTTGCTCAGACCATGGCGGCTAAAGCAGTAGATAAACTGCCAGTGACTTTTGGTAGTTTTGTGCACCAGATCCCAGAAGGCTTCTACCCCGGGGAGGACTCTACTCTGCCCGCGTCGGTGACCATCTTCCCCAATGTGGATCTGGGGGGACCTTTGATTCAGATGAGCGGAGTGACAGGAGATGGAATGATCAGTGTGGATATGAATAATGACAAGCGGTCGCTGGATTTCTCCTACTCGTCCAACTACCCCTTGGCCCCTAGGACTCAGCCGATCGCCTATATGGGCAAGATCTCCATTGATCACCAGTACTCGGGCTCCGGCTGGAACACAGAAGGGATCTTCAATCTAGTGAGCGCCGCCAGTCTCCTGGGGGTCCCGCCCTCCTCCTGCTCCTCCACCAGCTCCTCCAACGCCTCCTCGGGGTCCCCCAACCTGAGCTGCAGCATGTCGCACCCCCAAAGTGACCTGGAGCACATCTACTCGCCCCCCCCATACTCCAGCTGTAATGAGATCTACCAGGACCCCCTCCGCTTTCCATGTGGTTCGCCCACAGCGGCCTCCTTACCCCCGCCCCCCTCTTACCCTTCTCCCAAGGGGGCGTCGGACGGGGGGATGTTCCCAATGATCCCCGACTACTCGGCGCTCTTCCCCCCCCAGTGCCAGAGAGACTTACATTCCGATAGGAAACCCTTCCCTTGCCCCCGTCACCCCTCACCCCTCTCCACCATCCGCAACTTCACTTTGGGGGGCTCCAGCGAGGGGCCCAGACTCGCCAGCGCTTACAGCCCCCAGAACTTACCCCTCCGGCCCATCCTCAGACCCAGAAAATACCCCAACCGCCCCAGTAAGACCCCAGTCCACGAGAGGCCGTACCCGTGCCCGGCGGAGGGTTGCGACAGACGCTTCTCTCGCTCCGACGAACTGACGCGACACATCCGAATCCACACGGGCCACAAACCCTTCCAGTGCCGGATCTGCATGAGAAACTTCAGCCGCAGCGACCACTTGACCACTCACATCCGGACACACACCGGCGAGAAGCCCTTTGCCTGCGATTACTGCGGCAGAAAGTTCGCGCGGAGCGACGAGCGCAAAAGACACACCAAGATCCACCTGCGGCAGAAGGAGCGGAAGAACTCGGCAACAGCGGCGTGGCGGCAACACGTCGCAAGAACGTCCCTTAAGCCTCAGTCCGGCAGGGACCGGCAGCCATGTGCTCTACTGGGTCCGGCAGCGGCCCATTGGGACTCGATAGATCCTAACAGGACAGGCTGACACTTACACAATGTCATCAAGGGATCAATTCATCCAGGTCTGGACTGAGAATCAAAATAGACCCTGGCATTATAGGTACACAGAGGTCCAATCAG
Protein		Refseq >NP_001093725\|early growth response 2 (Krox-20 homolog) [Xenopus (Silurana) tropicalis] MAAKAVDKLPVTFGSFVHQFPEGIYPGEDSTLPASVTIFPNVDLGGPFDQMNSVTGDGMISVDMNNEKRSLDFSYSSNYPSAPRSQPLAYMGKFSFDPQYPGAGWNTEGIFNIVSAASILGVPPSSSSSTTSSNASSGSPNLSCSMAHPQSDMDHIYSPPPYSSCNEIYQDPSAFIGTSTGAPYPPPSYPSPKGASDGSVFPMIPDYSALFPPQCQRDLHSMPDRKPFPCPLDSIRVPPPLTPLSTIRNFTLGGSSNEGSRLPSAYSPHNLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKNSATAAPSGSATQERPLSLSPAGTGNSMCSTGSSSGQLGLCPSRTG	Refseq >NP_001079248\|early growth response protein 2 [Xenopus laevis] MAAKAVDKLPVTFGSFVHQIPEGFYPGEDSTLPASVTIFPNVDLGGPLIQMSGVTGDGMISVDMNNDKRSLDFSYSSNYPLAPRTQPIAYMGKISIDHQYSGSGWNTEGIFNLVSAASLLGVPPSSCSSTSSSNASSGSPNLSCSMSHPQSDLEHIYSPPPYSSCNEIYQDPLRFPCGSPTAASLPPPPSYPSPKGASDGGMFPMIPDYSALFPPQCQRDLHSDRKPFPCPRHPSPLSTIRNFTLGGSSEGPRLASAYSPQNLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKNSATAAWRQHVARTSLKPQSGRDRQPCALLGPAAAHWDSIDPNRTG UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.42791	Xl.1086
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		135 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	EGR2	OMIM:607678 OMIM:145900 OMIM:605253
mouse		MGI	Egr2	All(10) Targeted, knock Out(3) Targeted, other(7)
zebrafish		ZFIN ZFIN	egr2b egr2a	5 Lines(s)

Publications
First:		Conserved segmental expression of Krox-20 in the vertebrate hindbrain and its relationship to lineage restriction. [Development 1991]
Most recent:		The XenopusTGFBI is required for embryogenesis throughregulation of canonical Wnt signalling. [Dev Biol 2013]
		View All Papers 45 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		nucleic acid binding zinc ion binding
Biological:
Cellular Component:		nucleus
EC:
KOG:		[R] FOG: Zn-finger

Reagents		tropicalis	laevis
Clones			EXRC - 2 clone(s)
		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		StrJgi.4574.1.S1_at [+] Str.35364.2.A1_at Str.35364.1.S1_s_at Str.42791.1.S1_at StrEns.7472.1.S1_s_at	Xl.1086.1.S1_at
Affymetrix 2.0			Xl2.1086.1.S1_at

Symbol legend[+]