Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (256) GO Terms (5) Nucleotides (57) Proteins (22) Interactants (815) Wiki
XB-GENEPAGE- 853289

Gene Symbol: egr2

Gene Name: early growth response 2 (Krox-20 homolog)

Synonyms: XKr20 , EGR-2 , Krox-20 , XKrox-20 , krox20
Add Xenopus synonyms , Nomenclature history


Gene Function: zinc finger transcription factor

Protein Function:
Sequence-specific DNA-binding transcription factor.


Interactants: YYY

OMIM Disease Associations: CHARCOT-MARIE-TOOTH DISEASE, DEMYELINATING, TYPE 1D; CMT1D [+]
1/3
 
Xenbase Gene ID XB-GENE-853290 XB-GENE-866474 XB-GENE-17340379
Gene Symbol egr2 egr2.L egr2.S
Chromosome Chr07 chr7L
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq TrEMBL Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.42791 Xl.1086
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 207 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine egr2 egr2.L egr2.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards EGR2 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Egr2 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN ZFIN egr2b egr2a ZFIN Ensembl
chicken
GEISHA EGR2 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Conserved segmental expression of Krox-20 in the vertebrate hindbrain and its relationship to lineage restriction. [Development 1991]
Most recent: Developmental neurogenesis in mouse and Xenopus is impaired in the absence of Nosip. [Dev Biol 2017]
View All Papers 83 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 5 terms 5 terms 0 term
EC
PANTHER egr2
KEGG Pathways K12496 K12496
KOG [R] FOG: Zn-finger
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones   EXRC - 2 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Affymetrix 1.0 StrJgi.4574.1.S1_at [+] Xl.1086.1.S1_at
Affymetrix 2.0 Xl2.1086.1.S1_at

Symbol legend[+]

My Xenbase: [ Log-in / Register ]
version: [4.5.0]

Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556