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Summary Expression Gene Literature (28) GO Terms (15) Nucleotides (185) Proteins (32) Interactants (412) Wiki
XB-GENEPAGE- 853411

Gene Symbol: egr1

Gene Name: early growth response 1

Synonyms: Xegr-1 , tis8 , at225 , g0s30 , ngfi-a , znf225 , krox-24 , zif-268 , egr-1 , egr , egr1-a , egr1-b
Add Xenopus synonyms , Nomenclature history


Gene Function: zinc finger transcription factor

Protein Function :
Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine ...[+]


Interactants: Loading ...

Disease Ontology Associations:

OMIM Disease Associations: EARLY GROWTH RESPONSE 1; EGR1
1/3
 
Xenbase Gene ID XB-GENE-853412 XB-GENE-853419 XB-GENE-6252570
Gene Symbol egr1 egr1.L egr1.S
Chromosome Chr03 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq Swiss-Prot TrEMBL Refseq Swiss-Prot TrEMBL Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.39717 [+] Xl.637 Xl.46707
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 22 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine egr1 egr1.L egr1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards EGR1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Egr1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR egr1 ZFIN Ensembl
chicken
GEISHA EGR1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: A nerve growth factor-induced gene encodes a possible transcriptional regulatory factor. [Science 1987]
Most recent: Brg1 chromatin remodeling ATPase balances germ layer patterning by amplifying the transcriptional burst at midblastula transition. [PLoS Genet 2017]
View All Papers 3 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 15 terms 13 terms 11 terms
PANTHER egr1
KEGG Pathways K09203 K09203 K09203
KOG [R] FOG: Zn-finger
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Morpholino egr1 MO1 , egr1 MO2 egr1 MO1 , egr1 MO2 egr1 MO1 , egr1 MO2
ORF egr1 ORF2 egr1 ORF1
Affymetrix 1.0 Str.27206.2.S1_at [+] Xl.637.1.A1_at
Affymetrix 2.0 Xl2.637.1.S1_s_at

Symbol legend[+]
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