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XB-GENEPAGE-
853411
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Gene Symbol: egr1
Gene Name: early growth response 1 Synonyms: Xegr-1 , tis8 , at225 , g0s30 , ngfi-a , znf225 , krox-24 , zif-268 , egr-1 , egr , egr1-a , egr1-b Add Xenopus synonyms , Nomenclature history Gene Function: zinc finger transcription factor Protein Function  :
Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine ...[+]
Interactants: Loading ... 
Disease Ontology Associations: OMIM Disease Associations: EARLY GROWTH RESPONSE 1; EGR1 |
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1/3 | Xenbase Gene ID | XB-GENE-853412 | XB-GENE-853419 | XB-GENE-6252570 | ||||||||||
| Gene Symbol | egr1 | egr1.L | egr1.S | ||||||||||
| Chromosome | Chr03 | chr3L | chr3S | ||||||||||
| Molecules | tropicalis | laevis.L | laevis.S | ||||||||||
| Gene |
Genomic sequence
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Genomic sequence
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Genomic sequence
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| CDS |
Gene model
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Entrez Gene
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Entrez Gene
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Entrez Gene
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| mRNA |
Refseq
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Refseq
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Refseq
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| Protein
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Refseq
Swiss-Prot
TrEMBL
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Refseq
Swiss-Prot
TrEMBL
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Refseq
Swiss-Prot
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| Genomic | tropicalis | laevis.L | laevis.S | ||||||||||
| Genome Browser |
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| Links |
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| Genomic Synteny | Genomicus | ||||||||||||
| Expression | tropicalis | laevis.L | laevis.S | ||||||||||
| Ensembl | Ensembl | ||||||||||||
| UniGene | Str.39717 [+] | Xl.637 | Xl.46707 | ||||||||||
| RNA-Seq profile | Stage profile: |
Stage profile:
Tissue heatmap:
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| Experimental regulation |
Regulation heatmap:
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| Images | 22 expression image(s) for tropicalis and laevis | ||||||||||||
| Data Mining | tropicalis | laevis.L | laevis.S | ||||||||||
| XenMine | egr1 | egr1.L | egr1.S | ||||||||||
| Phenotype | tropicalis | laevis.L | laevis.S | ||||||||||
| Smith Morpholino Screen | |||||||||||||
| Orthology |
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| human |
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| mouse |
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| zebrafish |
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| chicken |
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| fruit fly |
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| worm |
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| Publications | |||||||||||||
| First: | A nerve growth factor-induced gene encodes a possible transcriptional regulatory factor. [Science 1987] | ||||||||||||
| Most recent: |
Brg1 chromatin remodeling ATPase balances germ layer patterning by amplifying the transcriptional burst at midblastula transition. [PLoS Genet 2017]
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| View All Papers 3 paper(s) referencing morpholinos | |||||||||||||
| Functional Ontologies | tropicalis | laevis.L | laevis.S | ||||||||||
| GO | 15 terms | 13 terms | 11 terms | ||||||||||
| PANTHER | egr1 | ||||||||||||
| KEGG Pathways | K09203 | K09203 | K09203 | ||||||||||
| KOG |
[R] FOG: Zn-finger
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| Reagents | tropicalis | laevis.L | laevis.S | ||||||||||
| CRISPR / TALEN | CRISPR tools | CRISPR tools | CRISPR tools | ||||||||||
| Clones | |||||||||||||
| GE Dharmacon | GE Dharmacon | GE Dharmacon | |||||||||||
| Source BioScience | Source BioScience | Source BioScience | |||||||||||
| Morpholino | egr1 MO1 , egr1 MO2 | egr1 MO1 , egr1 MO2 | egr1 MO1 , egr1 MO2 | ||||||||||
| ORF | egr1 ORF2 | egr1 ORF1 | |||||||||||
| Affymetrix 1.0 | Str.27206.2.S1_at [+] | Xl.637.1.A1_at | |||||||||||
| Affymetrix 2.0 | Xl2.637.1.S1_s_at | ||||||||||||
Symbol legend[+]
