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Summary Expression Gene Literature (37) GO Terms (21) Nucleotides (200) Proteins (47) Interactants (558) Wiki
XB-GENEPAGE-853411
Gene Symbol:
egr1

Gene Name:
early growth response 1

Synonyms:
Xegr-1 , tis8 , at225 , g0s30 , ngfi-a , znf225 , krox-24 , zif-268 , egr-1 , egr , egr1-a , egr1-b ( Add synonyms , Nomenclature history )

Gene Function:
zinc finger transcription factor

Protein Function :
Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine ...[+]


InterPro :
P-loop NTPase , ATPase ArsA/GET3 euk , Anion-transp ATPase-like dom , ATPase ArsA/GET3 [+]

Interactants:
Loading ...

Diseases: 


External Links:
1/3
 
Xenbase Gene ID XB-GENE-853412 XB-GENE-853419 XB-GENE-6252570
Gene Symbol egr1 egr1.L egr1.S
Chromosome Chr3 chr3L chr3S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100038164
399162
414518
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine egr1 egr1.L egr1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards EGR1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Egr1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Egr1 Ensembl
zebrafish
ZFIN, AGR egr1 ZFIN Ensembl
chicken
GEISHA EGR1 Ensembl
fruit fly
worm
Publications
First A nerve growth factor-induced gene encodes a possible transcriptional regulatory factor., Science 1987  
Most Recent The role of nitric oxide during embryonic wound healing., BMC Genomics 2019                                                
All View All Papers 4 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 20 terms 16 terms 12 terms
PANTHER egr1
KEGG Pathways K09203 K09203 K09203
KOG [R] FOG: Zn-finger
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks egr1
Morpholinos (on-target & off-target) egr1 MO1 , egr1 MO2
ORFs egr1.L ORF1 egr1.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info