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Summary Expression Gene Literature (88) GO Terms (15) Nucleotides (426) Proteins (54) Interactants (258) Wiki
XB-GENEPAGE-853954
Gene Symbol:
ocln

Gene Name:
occludin

Synonyms:
occludin , ocln-a , ocln-b ( Add synonyms , Nomenclature history )

Gene Function:
RNA polymerase II elongation factor

Protein Function :
May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.


InterPro :
PNMA , Znf CCHC sf , Znf CCHC , Occludin ELL [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
pseudo-TORCH syndrome 1

OMIM:
PSEUDO-TORCH SYNDROME 1; PTORCH1

External Links:
 
Xenbase Gene ID XB-GENE-853955 XB-GENE-6253861 XB-GENE-866529
Gene Symbol ocln ocln.L ocln.S
Chromosome Chr1 chr1L chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 548702
108717687
398133
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein NCBI Protein  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine ocln ocln.L ocln.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards OCLN OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Ocln MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Ocln Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR oclna oclnb ZFIN Ensembl
chicken
GEISHA OCLN Ensembl
fruit fly
worm
Publications
First A synthetic peptide corresponding to the extracellular domain of occludin perturbs the tight junction permeability barrier., J Cell Biol 1997              
Most Recent Transcriptome profiling reveals male- and female-specific gene expression pattern and novel gene candidates for the control of sex determination and gonad development in Xenopus laevis., Dev Genes Evol 2019          
All View All Papers 2 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 15 terms 4 terms 4 terms
PANTHER ocln
KEGG Pathways K06088 K06088 K06088
KOG [K] RNA polymerase II elongation factor
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks ocln
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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