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Summary Expression Gene Literature (405) GO Terms (14) Nucleotides (249) Proteins (49) Interactants (839) Wiki
XB-GENEPAGE-853991
Gene Symbol:
pou2f1

Gene Name:
POU class 2 homeobox 1

Synonyms:
OTF-1 , NF-A1 , XOct1 , oct1 , pou2f1r , oct-1 ( Add synonyms , Nomenclature history )

Gene Function:
homeodomain transcription factor

Protein Function :
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and histone H2B. Acts downstream of Notch signaling du...[+]



Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-853992 XB-GENE-17345040 XB-GENE-853997
Gene Symbol pou2f1 pou2f1.L pou2f1.S
Chromosome Chr2 chr2L chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 549091
779060
399316
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. NCBI Protein NCBI Protein  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine pou2f1 pou2f1.L pou2f1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards POU2F1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Pou2f1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Pou2f1 Ensembl
zebrafish
chicken
GEISHA POU2F1 Ensembl
fruit fly
worm
Publications
First Anti-OTF-1 antibodies inhibit NFIII stimulation of in vitro adenovirus DNA replication., Nucleic Acids Res 1989  
Most Recent Sorafenib Activity and Disposition in Liver Cancer Does Not Depend on Organic Cation Transporter 1., Clin Pharmacol Ther 2020  
All View All Papers 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 13 terms 5 terms 11 terms
PANTHER pou2f1
KEGG Pathways K09364 K09364
KOG [K] Transcription factor OCT-1, contains POU and HOX domains
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks pou2f1
Morpholinos pou2f1 MO1 pou2f1 MO1 pou2f1 MO1
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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