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Summary Expression Gene Literature (3) GO Terms (9) Nucleotides (209) Proteins (39) Interactants (54) Wiki
XB-GENEPAGE-855724
Gene Symbol: kmt2d

Gene Name: lysine methyltransferase 2D

Synonyms: mll2 ( Add synonyms , Nomenclature history )

Gene Function: zinc-finger-like PHD finger, transcription factor

Protein Function :

Interactants: Loading ...
Disease Ontology: Kabuki syndrome

OMIM Diseases: KABUKI SYNDROME 1; KABUK1

 
Xenbase Gene ID XB-GENE-855725 XB-GENE-6486303 XB-GENE-17340804
Gene Symbol kmt2d kmt2d.L kmt2d.S
Chromosome Chr02 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model Gene model
Entrez Gene: 100494109
Entrez Gene: 108708548
Entrez Gene: 108708990
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein TrEMBL NCBI Protein NCBI Protein
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine kmt2d kmt2d.L kmt2d.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards KMT2D OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Kmt2d MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR kmt2d ZFIN Ensembl
chicken
GEISHA KMT2D Ensembl
fruit fly
worm
WORMBASE
Publications
First WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development., Cell 2005    
Most Recent Loss of function of Kmt2d, a gene mutated in Kabuki syndrome, affects heart development in Xenopus laevis., Dev Dyn 2019                    
All View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 9 terms 0 term 0 term
PANTHER kmt2d
KEGG Pathways
KOG [R] Putative transcription factor HALR/MLL3, involved in embryonic development
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon
Morpholino kmt2d MO1 , kmt2d MO2 kmt2d MO1 , kmt2d MO2 kmt2d MO1 , kmt2d MO2
Affymetrix 1.0 Str.29973.1.S1_at [+] Xl.16861.1.S1_at
Affymetrix 2.0 Xl2.13588.1.S1_at [+]

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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Version: 4.12.1


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