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Summary Expression Gene Literature (9) GO Terms (9) Nucleotides (76) Proteins (38) Interactants (255) Wiki
Gene Symbol:

Gene Name:
kringle containing transmembrane protein 2

krm2 , kremen 2 ( Add synonyms , Nomenclature history )

Gene Function:
dickkopf receptor, acetylglucosaminyltransferase

Protein Function :
Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6.

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External Links:
Xenbase Gene ID XB-GENE-855741 XB-GENE-17344872 XB-GENE-866619
Gene Symbol kremen2 kremen2.L kremen2.S
Chromosome Chr09 chr9_10L chr9_10S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 780393
mRNA RefSeq NCBI Nucleotide RefSeq
Protein RefSeq NCBI Protein RefSeq
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine kremen2 kremen2.L kremen2.S
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
HGNC AGR, OMIM:Gene, GeneCards KREMEN2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
MGI, AGR Kremen2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
RGD, AGR Kremen2 Ensembl
fruit fly
First Kremen proteins interact with Dickkopf1 to regulate anteroposterior CNS patterning., Development 2002          
Most Recent RARĪ³ is required for mesodermal gene expression prior to gastrulation in Xenopus., Development 2018                            
All View All Papers 3 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 7 terms 1 terms 3 terms
PANTHER kremen2
KEGG Pathways K23091 K23091 K23091
KOG [GO] beta-1,6-N-acetylglucosaminyltransferase, contains WSC domain
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks kremen2
Morpholinos kremen2 MO1 , kremen2 MO2 kremen2 MO1 , kremen2 MO2 kremen2 MO1 , kremen2 MO2
ORFs kremen2 ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience

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