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Summary Expression Gene Literature (48) GO Terms (8) Nucleotides (286) Proteins (29) Interactants (188) Wiki
XB-GENEPAGE- 483949

Gene Symbol: tacc3

Gene Name: transforming acidic coiled-coil containing protein 3

Synonyms: maskin , xmaskin , eric1
Add Xenopus synonyms , Nomenclature history


Gene Function: Projectin/twitchin and related proteins

Protein Function:
Maternal RNA in oocytes remains in a dormant state as masking outcompetes eif4g to bind eif4e, thereby preventing translation. During oocyte maturation this complex dissolves and eif4g binds eif4e to a...[+]


Interactants: YYY

OMIM Disease Associations: BLADDER CANCER
 
Xenbase Gene ID XB-GENE-483950 XB-GENE-17343957 XB-GENE-865032
Gene Symbol tacc3 tacc3.L tacc3.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq Refseq TrEMBL Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.5836 Xl.25749 Xl.60072
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 6 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine tacc3 tacc3.L tacc3.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards TACC3 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Tacc3 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN tacc3 ZFIN Ensembl
chicken
GEISHA TACC3 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Maskin is a CPEB-associated factor that transiently interacts with elF-4E. [Mol Cell 1999]
Most recent: The microtubule plus-end-tracking protein TACC3 promotes persistent axon outgrowth and mediates responses to axon guidance signals during development. [Neural Dev 2017]
View All Papers 2 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 0 term 0 term 8 terms
EC
PANTHER tacc3
KEGG Pathways K14283 K14283
KOG [Z] Projectin/twitchin and related proteins
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Antibody Tacc3 Ab1 , Tacc3 Ab2 Tacc3 Ab1 , Tacc3 Ab2
Morpholino tacc3 MO1 , tacc3 MO2 tacc3 MO1 , tacc3 MO2 tacc3 MO1 , tacc3 MO2
ORF tacc3 ORF1
Affymetrix 1.0 Str.5836.1.S1_a_at Xl.580.1.S1_at
Affymetrix 2.0 Xl2.580.1.S1_a_at

Symbol legend[+]

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