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Summary Expression Gene Literature (816) GO Terms (10) Nucleotides (234) Proteins (33) Interactants (2250) Wiki
XB-GENEPAGE- 478788

Gene Symbol: tbxt

Gene Name: T-box transcription factor T

Synonyms: Xbra , X-bra , bra , Xbrachyury , brachyury , ntl , t-a , t-b , t
Add Xenopus synonyms , Nomenclature history


Gene Function: nuclear transcription factor

Protein Function :
Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Causes dorsal mesodermal differentiation of animal cap ectoderm when co-expressed with wnt8 and ...[+]


Interactants: Loading ...

Disease Ontology:
  

OMIM Diseases:
   NEURAL TUBE DEFECTS, SUSCEPTIBILITY TO; NTD [+]
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Xenbase Gene ID XB-GENE-478789 XB-GENE-6255736 XB-GENE-865212
Gene Symbol tbxt tbxt.L tbxt.S
Chromosome Chr05 chr5L chr5S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq TrEMBL TrEMBL Refseq TrEMBL Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.55517 [+] Xl.7970 Xl.514
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 464 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine tbxt tbxt.L tbxt.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tgas116l23      
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards TBXT OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR T MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR tbxtb tbxta ZFIN Ensembl
chicken
GEISHA T Ensembl
fruit fly
FLYBASE t Ensembl
worm
WORMBASE
Publications
First: Expression pattern of the mouse T gene and its role in mesoderm formation. [Nature 1990]
Most recent: Early specification and development of rabbit neural crest cells. [Dev Biol 2018]
View All Papers 197 paper(s) referencing morpholinos 9 paper(s) referencing OMIMs 12 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 4 terms 4 terms 10 terms
PANTHER tbxt
KEGG Pathways K10172 K10172 K10172
KOG [K] TBX2 and related T-box transcription factors
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 2 clone(s)   EXRC - 2 clone(s)
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Antibody T Ab1 , T Ab2 T Ab1 , T Ab2 T Ab1 , T Ab2
Morpholino t MO1 , t MO2 , t MO3 , t MO4 t MO1 , t MO2 , t MO3 , t MO4 t MO1 , t MO2 , t MO3 , t MO4
ORF tbxt ORF1 , tbxt ORF1 tbxt.L ORF1 tbxt.S ORF1
Affymetrix 1.0 Str.10814.1.S1_a_at [+] Xl.514.1.S1_at
Affymetrix 2.0 Xl2.7970.1.S1_at Xl2.514.1.S1_at

Symbol legend[+]
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