Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (33) GO Terms (11) Nucleotides (138) Proteins (21) Interactants (646) Wiki

Gene Symbol: dand5

Gene Name: DAN domain family member 5, BMP antagonist

Synonyms: 51-B6 , xCoco , coco , cer2 , crl2 , cerl2 , dante , grem3 , cktsf1b3 , S10-51-B6 , cerl2 , charon ( Add Xenopus synonyms , Nomenclature history )

Gene Function: maternal BMP/TGFbeta/Wnt inhibitor

Protein Function :
Plays an important role in regulating the left-right axis by blocking a tgfb1 cascade in the right posterior paraxial mesoderm. Functions as an inhibitor of bmp, tgfb1, nodal, activin and wnt signaling...[+]

Interactants: Loading ...
Disease Ontology:

OMIM Diseases:

Xenbase Gene ID XB-GENE-480809 XB-GENE-17340923 XB-GENE-865412
Gene Symbol dand5 dand5.L dand5.S
Chromosome Chr03 chr3L Scaffold20
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq TrEMBL Swiss-Prot Swiss-Prot TrEMBL Refseq Swiss-Prot Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine dand5 dand5.L dand5.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
MOD Entrez Gene Genetic Phenotypes Gene Expression
OMIM:Gene, HGNC, GeneCards DAND5 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
MGI, AGR Dand5 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
ZFIN, AGR dand5 ZFIN Ensembl
fruit fly
First Xenopus Dan, a member of the Dan gene family of BMP antagonists, is expressed in derivatives of the cranial and trunk neural crest., Mech Dev 2001      
Most Recent Asymmetric distribution of biomolecules of maternal origin in the Xenopus laevis egg and their impact on the developmental plan., Sci Rep 2018  
All View All Papers 4 paper(s) referencing morpholinos 33 paper(s) referencing OMIMs 33 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 7 terms 1 terms 6 terms
KEGG Pathways
Reagents tropicalis laevis.L laevis.S
GE Dharmacon GE Dharmacon GE Dharmacon
Antibody Dand5 Ab1
Morpholino dand5 MO1 , dand5 MO2 dand5 MO1 , dand5 MO2 dand5 MO1 , dand5 MO2
ORF dand5.S ORF1
Affymetrix 1.0 Str.3903.1.S1_at [+] Xl.25775.1.A1_at
Affymetrix 2.0 Xl2.51884.2.S2_at [+]

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.11.1

Major funding for Xenbase is provided by grant P41 HD064556