Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (26) GO Terms (11) Nucleotides (136) Proteins (20) Interactants (564) Wiki
XB-GENEPAGE- 480808

Gene Symbol: dand5

Gene Name: DAN domain family member 5, BMP antagonist

Synonyms: 51-B6 , xCoco , coco , cer2 , crl2 , cerl2 , dante , grem3 , cktsf1b3 , S10-51-B6
Add Xenopus synonyms , Nomenclature history


Gene Function: maternal BMP/TGFbeta/Wnt inhibitor

Protein Function:
Plays an important role in regulating the left-right axis by blocking a tgfb1 cascade in the right posterior paraxial mesoderm. Functions as an inhibitor of bmp, tgfb1, nodal, activin and wnt signaling...[+]


Interactants: YYY

OMIM Disease Associations:
 
Xenbase Gene ID XB-GENE-480809 XB-GENE-17340923 XB-GENE-865412
Gene Symbol dand5 dand5.L dand5.S
Chromosome Chr03 chr3L Scaffold20
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 9.1 JBrowse 9.1 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq TrEMBL Swiss-Prot TrEMBL Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.3903 [+] Xl.51884
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 6 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine dand5 dand5.L dand5.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards DAND5 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Dand5 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN dand5 ZFIN Ensembl
chicken
fruit fly
worm
WORMBASE
Publications
First: Xenopus Dan, a member of the Dan gene family of BMP antagonists, is expressed in derivatives of the cranial and trunk neural crest. [Mech Dev 2001]
Most recent: Leftward Flow Determines Laterality in Conjoined Twins. [Curr Biol 2017]
View All Papers 4 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 7 terms 1 terms 6 terms
EC
PANTHER dand5
KEGG Pathways
KOG
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Antibody Dand5 Ab1
Morpholino dand5 MO1 , dand5 MO2 dand5 MO1 , dand5 MO2 dand5 MO1 , dand5 MO2
ORF dand5 ORF1
Affymetrix 1.0 Str.3903.1.S1_at [+] Xl.25775.1.A1_at
Affymetrix 2.0 Xl2.51884.2.S2_at [+]

Symbol legend[+]

My Xenbase: [ Log-in / Register ]
version: [4.5.0]

Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556