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Summary Expression Gene Literature (2) GO Terms (5) Nucleotides (152) Proteins (20) Interactants (185) Wiki
XB-GENEPAGE- 481538

Gene Symbol: f2

Gene Name: coagulation factor II, thrombin

Synonyms: coagulation factor II
Add Xenopus synonyms , Nomenclature history


Gene Function: blood coagulation

Protein Function :
Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, ...[+]


Interactants: Loading ...

Disease Ontology Associations: PROTHROMBIN DEFICIENCY [+]

OMIM Disease Associations: COAGULATION FACTOR II; F2 [+]
 
Xenbase Gene ID XB-GENE-481539 XB-GENE-865465 XB-GENE-17331609
Gene Symbol f2 f2.L f2.S
Chromosome Chr04 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq TrEMBL TrEMBL TrEMBL Refseq TrEMBL Refseq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.8528 Xl.62198 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 2 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine f2 f2.L f2.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards F2 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR F2 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR f2 ZFIN Ensembl
chicken
GEISHA F2 Ensembl
fruit fly
worm
WORMBASE
Publications
First: RNA-Seq and microarray analysis of the Xenopus inner ear transcriptome discloses orthologous OMIM(®) genes for hereditary disorders of hearing and balance. [BMC Res Notes 2015]
Most recent: Quantitative Proteomics After Spinal Cord Injury (SCI) in a Regenerative and a Nonregenerative Stage in the Frog Xenopus laevis. [Mol Cell Proteomics 2018]
View All Papers 1 paper(s) referencing Disease Ontologies
Functional Ontologies tropicalis laevis.L laevis.S
GO 5 terms 5 terms 5 terms
PANTHER f2
KEGG Pathways K01313 K01313 K01313
KOG [E] Trypsin
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
ORF f2 ORF1 lpa-prov ORF1
Affymetrix 1.0 Str.8528.1.S1_at
Affymetrix 2.0 Xl2.29409.1.S1_at [+] Xl2.22112.1.S1_at

Symbol legend[+]
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