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Summary Expression Gene Literature (28) GO Terms (11) Nucleotides (417) Proteins (109) Interactants (427) Wiki
XB-GENEPAGE-486121
Gene Symbol:
btrc

Gene Name:
beta-transducin repeat containing E3 ubiquitin protein ligase

Synonyms:
Beta-TrCP , betaTrCP , fwd1 , fbw1a , fbxw1 , btrcp , fbxw1a , btrcp1 ( Add synonyms , Nomenclature history )

Gene Function:
F-box protein/ubiquitin protein ligase complex component

Protein Function :
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Proba...[+]


InterPro :
Beta-TrCP D , WD40 repeat CS , WD40 repeat dom sf , F-box dom [+]

Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-486122 XB-GENE-17339405 XB-GENE-865578
Gene Symbol btrc btrc.L btrc.S
Chromosome Chr7 chr7L chr7S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 549140
397988
394362
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein NCBI Protein  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine btrc btrc.L btrc.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards BTRC OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Btrc MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Btrc Ensembl
zebrafish
chicken
GEISHA BTRC Ensembl
fruit fly
worm
Publications
First Identification of new localized RNAs in the Xenopus oocyte by differential display PCR., Dev Genet 1996                  
Most Recent Claspin - checkpoint adaptor and DNA replication factor., FEBS J 2019  
All View All Papers 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 8 terms 1 terms 4 terms
PANTHER btrc
KEGG Pathways K03362 K03362
KOG [S] Beta-TrCP (transducin repeats containing)/Slimb proteins
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks btrc
Antibodies Btrc Ab1 Btrc Ab1
Morpholinos (on-target & off-target) btrc MO1 btrc MO1 btrc MO1
ORFs btrc.S ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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