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Summary Expression Gene Literature (21) GO Terms (21) Nucleotides (250) Proteins (51) Interactants (761) Wiki
XB-GENEPAGE-868099
Gene Symbol:
tle1

Gene Name:
transducin like enhancer of split 1

Synonyms:
grg1 , xgrg1 , esg , esg1 ( Add synonyms , Nomenclature history )

Gene Function:
transcriptional regulator

Protein Function :
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by r...[+]



Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-868100 XB-GENE-17341265 XB-GENE-6252455
Gene Symbol tle1 tle1.L tle1.S
Chromosome Chr1 Scaffold21
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2
CDS Gene model Gene model
Entrez Gene 100101799
779361
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine tle1 tle1.L tle1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards TLE1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Tle1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Tle1 Ensembl
zebrafish
tle2b Ensembl
chicken
GEISHA TLE1 Ensembl
fruit fly
worm
Publications
First Cloning and developmental expression of Xenopus cDNAs encoding the Enhancer of split groucho and related proteins., Gene 1997  
Most Recent Phosphorylation states change Otx2 activity for cell proliferation and patterning in the Xenopus embryo., Development 2018                              
All View All Papers 5 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 21 terms 0 term 2 terms
PANTHER tle1
KEGG Pathways
KOG [B] Transducin-like enhancer of split protein (contains WD40 repeats)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks tle1
Antibodies Tle1 Ab1 Tle1 Ab1 Tle1 Ab1
Morpholinos (on-target & off-target) tle1 MO1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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