Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (54) GO Terms (9) Nucleotides (98) Proteins (28) Interactants (252) Wiki
XB-GENEPAGE- 868376

Gene Symbol: nanos1

Gene Name: nanos homolog 1

Synonyms: nos1 , xcat-2 , xnos1 , xcat2
Add Xenopus synonyms , Nomenclature history


Gene Function: RNA binding

Protein Function:
Acts as a translational repressor. Can mediate repression affecting different steps in the translation process: cap-driven, IRES-driven, polyadenylated RNAs or nonpolyadenylated RNAs. Essential for the...[+]


Interactants: Loading ...

OMIM Disease Associations: SPERMATOGENIC FAILURE 12; SPGF12
 
Xenbase Gene ID XB-GENE-868377 XB-GENE-6252322 XB-GENE-17337752
Gene Symbol nanos1 nanos1.L nanos1.S
Chromosome scaffold_83 chr7L
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Swiss-Prot Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.66510 Xl.1145
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 24 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine nanos1 nanos1.L nanos1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards NANOS1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Nanos1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN nanos1 ZFIN Ensembl
chicken
GEISHA NANOS1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: The frog prince-ss: a molecular formula for dorsoventral patterning in Xenopus. [Genes Dev 1993]
Most recent: Maternal Dead-end 1 promotes translation of nanos1 by binding the eIF3 complex. [Development 2017]
View All Papers 4 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 8 terms 9 terms 0 term
EC
PANTHER nanos1
KEGG Pathways K18741 K18741
KOG [R] Nanos and related proteins
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Antibody Nanos1 Ab1 , Nanos1 Ab2 Nanos1 Ab1 , Nanos1 Ab2
Morpholino nanos1 MO1 nanos1 MO1 nanos1 MO1
Affymetrix 1.0 Str.3.1.S1_a_at Xl.1145.1.S1_at
Affymetrix 2.0 Xl2.1145.1.A1_at

Symbol legend[+]

My Xenbase: [ Log-in / Register ]
version: [4.6.0]

Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556