Gene Symbol: tgif2 Gene Name: TGFB-induced factor homeobox 2 Synonyms: xtgif2 Add Xenopus synonyms Gene Function: homeodomain transcription factor Interactants: odc1(2) , vegt(2) , a2m(1) , aurka(1) , bmp4(1) , c19orf25(1) , chrd(1) View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		NCBI Nucleotide >XM_002932851|PREDICTED: Xenopus (Silurana) tropicalis TGFB-induced factor homeobox 2, transcript variant 1 (tgif2), mRNA CTAATGAAAAGATAAACTTGCAAGTCTGGGGCTTCACTTTTAACTGCTCAGAGCTACATCTCCCTCCCCACCTACCTACCTACCTCCCATTCACTCACCTGGGGGAAGGTGACAAGAAGCTGAACCCATCAGGGAGCATTGGAGAATGATGAATTCGACTTTTGAAAGCCTAATGACCGACCATGAGATTGACCACAGCCTCCATACGGACAGCGGGGAAGATGAAGGCAGTTCAGAGCTTGACATTTCAGGTGCCAAGAGGAAACGAAGGGGAAACCTCCCGAAGGATGCTGTGAAAATCCTGCGGGACTGGCTTTTTGAGCACCGCTTCAACGCTTACCCATCAGAACAAGAGAAACTCAGTCTGTCTGGGCAAACCAACCTCACTGTCCTGCAGATCTGTAACTGGTTCATTAATGCCCGCCGACGAGTTTTACCTGAGCTTTTGCGCAAAGATGGGAAAGACCCGAACCAGTTCACTATTTCACGTAAAGGTGGAAAGTCACCAGAAATGCCTTCCCCGAGAACCCCCACGTCGCTGCCCAGCGTCCTGGTAATGCCCCCTACAACTGCTGTCCCTGCGAGGATACTCTCCGTGCCTCTGCTGTACCCGGTAGCACAGCCGGTGGCTAACCTGGTTAGTCATGACCTAATCTTGCCCAGTATGGTGCCCACCATCAAGACCGAAGAGGGTAGCACGACTGTTTTATTGCCCAAGAAACGTGCCCGAAGCCCAACACATGAACTTGTCAACACACCACCTCCTTCCCCCTCGCCCCCTCTGCTGTTCGGAGGGGCAAGCATTAGCAGACTGAACATTTTGGCACAAGTGGCAACAATGTGCATGGCAGAAATGGAAGCTGAAGAGGCAAAAAGGGAGGCTGCCCGCTCTGCTCTTACATCATTGTACAAGGCTGCACCAATCACGACAAGCACCCCCAATTAGAGTTGTGCTGTCCAACTGAATAAAGAGGGGGTCACATTCCTGAACTCCCCCCTTCTTTATGAACAGTTTTGCGGGGGCACTTAAAATGGATGCTGAGGAAACAAGGATTTAACCATGTGACCAAAAAGGACATTCTGGCCCCAAAGATGGTGCGCAAACATGGCTTCCATGCCTGCAAAGAATGCACAACCCCTGATCTTGAAATTCGGGGGACCTTTGCTGCATGTTGGATTGGGAAGCAAAAGAAAGGTCCAAATATATTTTCTCATAAAAGAAACTTTATCTGTTTACATTGAGTATTTGTCCCCACTTTGTGTGTTGGGGGGGAGATTGGAATTGGGATTAGGGGCAATAAGGCACCTTGGGGCAAGACTGGTCGGCATCTTCCTTACTCCTTCCCAGCAAAGTGCCCAGTGTTGTGTAAATATGCTGCTACCCCCCTCCCCTTTTGTGCACTTTATAGGTCAAAATGGCCACCGGTTCCGCAGCTTGATGAGAGTACCGAGTATCCTTCACACCACTACAGCTGGATTTCCAGAGTCGCTTAGGCCGCACACGATAATGACTGAGCCGAGTCTGCCATACTCGGCACCACTGTACACAGTTGTTTGCTAAATACCCAAGTGTGCTTAAGGGGATGAGATTTATGCTGATGTTGTTGACTAATCCTCATTTATTGAACTTCCTTCCTGACACTGTTTGACAACCTTGGCCTCTCCAGCTGTTCTCAAAGGGCTACAACTCCCAGCATCCCAGGGAGTCTGCTGGGAGCTGCCGTTTTCCAACAGTTCGAGCGATAAAGGTTGTCTAAATATACGAGTTTACCTTATTTTTTTTTTTATTTTATTTTTTTTTATTTTGAACTGTGAATGTGTAGTAAATACCATGTATCTATTACTCCGTATCTATATTATCCAGTATTTGGTGCAGAGAAGATGGGTTTGCTCTCTGACATTATGTAGACTGGAAAGTGGGACAGAGGAATGTTTTAGTTCCTTTGCTGCCTTACAATATATGTCATTTACTGCCTCCTCAGCAGGTTATATATACAGCTAAAGGGATTGTGGGTATGGGAGGGGGGTGGGAGGTATAGGGTCCCCATTCATTTTCCCTGAAGGCGCAGTTTATTTTCTGTACGGATAAGGGCACTGCCCAATTGCTTACAGCATTTTATAGTGATGTAGAACAGTATCATCTTGACCACTGGGGGAGCTGTTACATTATGTTTTTTACATCAATAGGCTGCAATAATAGGATCATTACTGGTCATGGCTATATGGTTGTCTATGTAGAATCTTCCAATATGGCAGCTCCCACTTATGCAGATAAGCATCCATGGTATTATATGTTACATGGGAATAACTGGAGGATGAGATCTGACTATAAATAACATGTATTTTACCTATTAAAAGGAGCAATTATGTGGAAATGGTCAAAAGAATGGTTTCATGCTCAGTTTTCATTGGCACACAGGGAGATTTGGGGCATTTTGGCCCCAACTGCTGATAGTAGCTGGATGGGGGGACAATATCACCCCCTATTCAAATGAAGAAATAATGGCCTGAATGCTTGGAGCCATGATTTCTGCCAATTGCAATAGAGGTCAAATATCCCCATGCGCAGTCACTACTTTCCCTACATGGTTAAATACCCAGAACCTCCTGTTGCATTGCCCCTGTGGGCAGGTACCCAAAAGAGCAGCATGTTATTGATCGTTACTGCCAAAAAGCAGTCGCAGGGTGGAAATGTTCCTGTAACACTTAACCCTTTACTTCCTGCAAAGATATTTAAATGGTTGATGTCTTATTTTTAAAAGCAGAGATGTACAGTACAGTGTTTATTGTAGTATTCTTGACATTGAGATATTAAAGGTTCAACCCTTCTTGCCCAATTAAAGCAGAAATATACCTTAAGTCTTATTTACGTCTGCATGAGGCCAGAGCTTAATGCCATTCGCTTGTGTTTATACATTTTGCCTATAGCAAGTTAACCTCATATGTCATTGTCTGCCTCTATGTACGGGGTATTTACCCTTTACAATATTGGGGAATCATTTTCTGTTGCAAATAAATTGACCTGCAAAGCTGCAGTCCACTGTATCCAAAGTGGCTGCTGGGAATTGTAGTCTTCTACTAGTTAGAGTGCAGCAGACTTGTTATTGGGTGCAAGGGAAGGCTTTGCGCTAGCTCTTTGCGCTTCAGACTCATTGTAAGTATAAGCCTAATCATTATACTAGTCTTACCCCATATTGGCCACTAGATGGCAGCATTACCACCTAGCAGGTCTAGTGATACAATTGTGTGTAAGTAAGATTTAACCCAAAATCCTCTTTAAAGTAATGGGTAAAATGAGCTATAAGAATAGGGGGGGTTTAAAGAGTAAAATACAGTAAAGGCATGTGAGATGGAGTAGTAAAACAGCCCCACTTATAAATAAGCTGTTAAAGTTTTTACGTCAGTGCAATGTCTTTATTCTAAATAGGATGAGCTAGAATTGTTTGTATTTTGGATCAGAATGGAACAAGTCACATTATTCCTATGAAATTACCTCTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGGAAAAAACATTTCATGTATTTTTTCATGCCGTAGAGTCATTAAATTATATGAACTGGGAGATATTTTGGCATGCCAGCAAAAGGTGAAGCAATAGGGTGTCTTGGCTGGGACAGCAGCACCCATTGCCCGTGAATCTCATTTATTGGTTTTTATGGTACAAGCTGTATGAATGTTTTAACAGATTATTTCTGTGTGCATTTTTTTTTTTTTATAAAATTTGTAATAAAAAAAGTGTTTTGGAAAGTAACA	Refseq >NM_001094168|Xenopus laevis TGFB-induced factor homeobox 2 (tgif2), mRNA CCTGAGGGGCAGGTGACAAGAAGCTCAACTCACCAGGAAGGAGTCAAGGATGATGAATTCTACTTTTGACAGCCTAGTGATAGACCACGAGATGGACCCCAGCCTCCATACGGACAGCGGGGAAGATGAAGGCAGTACAGAGCTTGATATTTCAGGTGCCAAGAGGAAACGCAGGGGAAACCTCCCAAAGGAGGCTGTGAAAATCCTGAGGGATTGGCTTTATGAGCACCGATTCAACGCTTACCCATCAGAGCAAGAGAAGCTGAGTCTGTCTGGGCAAACCAACCTCACAGTCCTGCAGATCTGTAACTGGTTTATAAACGCCCGCCGACGCATTTTACCTGAGCTACTGCGCAAGGATGGGAAAGACCCAAACCAATTCACAATTTCACGAAAAGGCGGGAAGTCACCAGAGATGTCTTCACCTTCACCAAGAACACCCACGCAACTGCCTAGTGTCTTGGTGATGCCCCCTACAACTACTGTCCCCGCAAGGATAGTGTCTATGCCTCTGCTGTACCCCGTAGCACAGTCGCTGACTAACCTGACAACCGTTAGTCATGACCTCATCTTGCCCAATATGGTGCCCACCATCAAGACTGAACAGTGTGGCACAACTGTTTTATTGCCCAAGAAACGGGCCCGGAGCCCAACAGATGAACTTGTCAACACTCCACCTCCTTCACCCTCACCCCCTCTGCTGTTCGGAGGGGCAAGTATTAGCCGACTAAACATTCTGGCCCAAGTGGCAACAATGTGCATGGCAGAAATGGAAGCTGAAGAGGCAAAAAGAGAGGCTGCCCGCTCTGCTCTTAATGCATTGTACAAGGCTGCACCAATCACGACCAGCACCCTCAATTAGAGTTGTGCTGTCCCACTAAATAAAGATGGGGGGGGTCACATTCCTAAATTTCCCCCGTCTTTATTGACTGTTTTGCTGGGGGCACTTACAATGGATGCTGGGAAAAATAACAATTTAAACATTTTGTGACCAAGAAGGACATTCCGGCCCCAAAGATGCTGCCCAAAAATGGCTTCCATGTCTGCAAAGAATGCACATCCCCTGATGTGAATGAAATTCAGGGGAACCTTTGCTGCACATTGGTTTGGGAGGTGAAAAAGAGGTCCAAATATATTTTCACATAAAAGAAACTTTATCTGTTTACAGTATTTATCCCCAGTCTTTCACTTTGCTTATTGGAGGGGAGATTGGGATTAGGGGCAATAAGGCACCTTGGGGCAAGACAGGCAGGTTGGCATCTTCCTTACTCCTTCCCAACAAAGTGCACAGTGCTGTGTTAATATGCTGCTACCCCCTTCCCCTTTTGTGCACTTTATAGGTCAAAATGGCCACCAGTTACGCAGCATACTAAGACTATGGAGTATCTTTCACACCACTACAGCTGGATTTCCAGAGTTGCTTAGACCGCACACTATAATGACTGAGCTGAGTCCGTCATACTTGGCACCACTGTACACAGTTGTTTGGTAATTACCCGAGTGTGCTTAAAGGGGATGAGATTTATGTTGATGTTGTTAACTATTCCTCATTTAAATGAACTTCCTTCCTGACACTGTTTGACTACATTGGCCTCTCCAGCTGTTAAGGAACGACTACAGCTCCCGGCATCCCAGAGAGCATGCTGGGAGTTGTCGATTCCCAACAGTTAGGGTGATCAAGGTTGTCTTAAAAAAAAACATTGAGTTTACCTTTTTTTTTTTATTTTGAACTGTGAATATGTAGTAAATACAGTGTATCTATTACTCCGTATCTATGTTATCCAGTATTTGGTGCAGAGAAGGTGAATTTGCTTTCTGACTTTATGTAGACTGGAAAGCAGGACAGAGGAATGTTTTAGTTCCTTTGCTGCCTTACATTATATGTCATTTACTGCCTCCTCAGCAGGGTATATATACAGCTGAAGGGATTAGGGAAAGGGAGGGTGGGAGGTATAGGGTCCCAAGTCATTTTTCATGCAAAAGACACATATGAAGGTGCAGTTTATTTCTTGTTTGCAGCATTTTATAAAGATGTAGAACAAGATCTTGACCACTAGGGGCGCTGTTACGTGCTTCCTTCACTGCATGTGAGTTGCTCTTACTAAGTAGAATAATACCCAGAACCCCCTCTTGCATTGCTTTGCCAAGGTGGAATTGGATTCCCAAAATACTCCCAGGAGCAGCATGTTATTGATTGTTACTAGGGATGCACTGAATGCACTATTTTTGATTCGGCCAAATCCTTCGTGAAAGATTCGGGCAGAATACCGAACCGGATCCAAACCCTAAATTGCATATTTAAATTAGGGGACTGAACAGAAGTAGTGGGGAACCTTTTTTTTTTTACTACCTTGTTATGTGACGAAAAGTAAAAATTCCCCTAACTCAACGTTGTAAATGTGCTTACAATTTGTTAAAAAAGTGTATGATGGACATTTCTGCAGACTGACCCCATGCACCTCTACCTTGCGTGTTTCGTGCCCTCCGGTACTTACTCATAGGTGATTGAGTAAGTATCGGAGGGAGCGAGATGCGTGGGGTGTGGGAGCATGGGGTCAGTCTTCAGAGGTGTTTTTATTGTATATTTTTTTGAATGAATTGTAGGCATGTTTACAACGTTTGAGTTATGGGAATTTTTTTTGAGATATTTGTGAAGTGTGCCTTGGGAAGCAGCACATTTCCCGGTAACACGAGTCCTTAGACTGACCTTTTTGAGTACTAGGACAAAAGTAACCTGATTTCCCTTCCTGCCCCTAATCTGCATATCCTAATTTACATATGCAAATTCGGGTTCAGCCAGGCACAAGGATTCTGCTGAATCCGAATCCTGCTGAAAAAGGCCGAATCCTGGATTTAGTGCATCCCTAATTGTTACTGCCAAAAAGCATCATTTTAACCTGTAACAGGATGAAAATATACCCATTAGACTCGCCCTCTATGTTCTGCATCATATATGAATTGTTGATGCCTTTTTTTTATGCAGAGATGTATAGTTACGGTGTTTCTTGTAGTGTTCTTCACATTCAGAGATATATATTAAAGGTTCTCGCCTTCACCAAATTTAAGCAGGAAAAAAAAAAAAAAAAAAAAA
Protein		NCBI Protein >XP_002932897|PREDICTED: homeobox protein TGIF2 isoform 1 [Xenopus (Silurana) tropicalis] MMNSTFESLMTDHEIDHSLHTDSGEDEGSSELDISGAKRKRRGNLPKDAVKILRDWLFEHRFNAYPSEQEKLSLSGQTNLTVLQICNWFINARRRVLPELLRKDGKDPNQFTISRKGGKSPEMPSPRTPTSLPSVLVMPPTTAVPARILSVPLLYPVAQPVANLVSHDLILPSMVPTIKTEEGSTTVLLPKKRARSPTHELVNTPPPSPSPPLLFGGASISRLNILAQVATMCMAEMEAEEAKREAARSALTSLYKAAPITTSTPN	Refseq >NP_001087637|TGFB-induced factor homeobox 2 [Xenopus laevis] MDPSLHTDSGEDEGSTELDISGAKRKRRGNLPKEAVKILRDWLYEHRFNAYPSEQEKLSLSGQTNLTVLQICNWFINARRRILPELLRKDGKDPNQFTISRKGGKSPEMSSPSPRTPTQLPSVLVMPPTTTVPARIVSMPLLYPVAQSLTNLTTVSHDLILPNMVPTIKTEQCGTTVLLPKKRARSPTDELVNTPPPSPSPPLLFGGASISRLNILAQVATMCMAEMEAEEAKREAARSALNALYKAAPITTSTLN

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.51993	Xl.7324
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		5 expression image(s) for tropicalis and laevis

Phenotype		tropicalis	laevis
Smith Morpholino Screen		tneu131c18

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	TGIF2
mouse		MGI	Tgif2	All(3) Targeted, other(3)
zebrafish

Publications
First:		Amplification and overexpression of aurora kinase A (AURKA) in immortalized human ovarian epithelial (HOSE) cells. [Mol Carcinog 2005]
Most recent:		Maternal Tgif1 regulates nodal gene expression in Xenopus. [Dev Dyn 2008]
		View All Papers 1 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		DNA binding transcription factor activity
Biological:		regulation of transcription, DNA-dependent
Cellular Component:		nucleus
EC:
KOG:		[K] Transcription factor MEIS1 and related HOX domain proteins

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.51993.1.S1_at	Xl.7324.1.S1_at
Affymetrix 2.0			Xl2.7324.1.S1_at [+] Xl2.7324.1.S2_at

Symbol legend[+]

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