frzb2 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (74)

Nucleotides (164)

Interactants (195)

XB-GENEPAGE-876717

Gene Symbol: frzb2 [provisional] Gene Name: frizzled-related protein 2 [provisional] Synonyms: crescent, frizzled related protein Add Xenopus synonyms Gene Function: secreted wnt antagonist Interactants: nkx2-5(15) , dkk1(10) , wnt8a(10) , frzb(9) , szl(9) , chrd(8) , fgf8(8) View All	1/4

XB-GENE-876718

XB-GENE-876726

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001016688\|Xenopus (Silurana) tropicalis frizzled-related protein 2 (frzb2), mRNA GAAACATTTGCCTTTAGTGCAGCGCCTATAATGGCCCCTCAGTCGTGTCAGAGTCTGGGAAAGCTGTGTTCCCAGGGGCAACTGATTGTTTTGTTGTGCTTCTTGACATGTGGCTCGCAGTCTATGTATTTGGACTTCTTCGGCAGCTCTTCAAGATGCACGCGGATCCCGAGGAGCATGGCTCTGTGCTATGACATTGGATATTCAGAGATGAGGATCCCCAACTTGCTGGAACATGACACAATGGCCGAGGTGATCCAACAATCCTCCAGCTGGTTACCGCTGCTGGCAAGGGAGTGCCACCCCGATGCAAGGATATTCCTGTGCTCCCTATTTGCACCTATTTGCCTGGATCGGTATATCTACCCATGCCGCAGTCTGTGTGAGGCAGTACGGGGCAGCTGTGCCCCTATAATGGCCTGCTATGGGTACCCATGGCCTGAGATACTCAGATGCGATAAGTTTCCTGAGGACCACGGCATGTGCATCTCACCCATCACAAATGGCACCGGTTCTACCCGCAGAACAGTGCCCCGAGCCAGCTGTAGGGACTGTGAACTTGAAGAAGCCAGCACAGCCAAGGAGATACTGGATACCTTCTGTGATAATGATTTTGTTGCCAAGGTCCGTATCACCAAAAAGAACATCACTTCGGCTAACCTGTACGACTTTGATTTGGATTCCAAACTCGAGATCCTGAAACACGGCTCCTTGCCTAAAACAGACGTCCTCCCTAGGCTTCAGCAGTGGCTGGATTTGGATGCTACCTGTGTGCAGAATATCATGCGTGGGACCCGCACAGGCATCTACGTGATTGGCGGAGAAGTGCAAGAGGACAAGGTAGTGGTGAACAATGCCTACGCTTGGCAGAAAAAGAACAAAAACCTGCAGTTTGCCGTACGGAAATGGAAGAATCATAAGTGTCGGCCATAGGAATTCCCATTTTGTTCTAATGCTGAGAATATATCTATATCTGTAAATATCTATGCTAACTTACTATAAAAAAAAAACTTTTTGGAAAAAAAAAAAAAAA	Refseq >NM_001088556\|Xenopus laevis frizzled-related protein 2 (frzb2), mRNA CTTTTGTGCATCCATAAGGAAAATCCCAATGGCCCCTCAGCTGTGTCAGAGCCTGGGAAAGCCACTGATTGTTTTGCTGTGCTTCTTGGCGTGTGGCTCGCAATCTATGTATCTGGACTTCTTTGGCAGCTCCTCAAGATGCATGCGAATCCCAAAGAGTATGGCTCTCTGCTATGACATTGGATATTCGGAGATGAGGATCCCCAACTTGCTGGAACATGAGACGATGGCCGAGGCAATCCAACAATCCTCAAGCTGGTTACCTCTTTTGGCAAGAGAGTGCCATCCTGATGCAAGAATATTCCTCTGCTCACTCTTTGCACCTATTTGCTTTGATCGGTATATCTTCCCATGTCGCAGTCTGTGTGAGGCTGTAAGGAGCAGCTGTGCCCCTATCATGGCCTGTTATGGGTACCCTTGGCCTGAGATCCTCAAATGCGATAAGTTTCCTGAAGACCACGGCATGTGTATCTCAACTATCACAAATGATACTGGCTCTACCCGTAGAACAGTGCCCCGAGCCAGCTGTAGAGACTGTGAACTTGAAGAAGGCAGCACTTCCAAGGAGATACTGGATACATTCTGCCATAATGATTTTGTTGCCAAGGTCCGTATCACCAAAAAGAACATCACTTCCGCTAACCTTTACGACTTTGATTTGGATTCCAAACTTGAGATCCTGAAACACGGCTCGTTGCCCAAAACAGACGTCCTTCCTAGGCTTCAGCAGTGGCTGGATCTGGATGCTACCTGTGTGCAGAATATCATGCGTGGGACCCGCACAGGCGTCTATGTGATTTGTGCAGAAGTGCAAGAGGGGAAGGTAGTGGTGAACAATGCCTACGCATGGCAGAAAAAGAACAAAAACCTGCATTTCGCTGTACGGAAATGGAAGAATCACAAGTGTCGACCATAGGAATTCCCAATTCGTTGTACAGAAACCAAAGTCCTGTGTTGTGAAATAGTAGAAGCAGGGGCATTCACGAGAACTGTATATAATACTGTATATATCTATGTTAACTTACTATAAAACCTTATTGATAAAAAGAGCGGAGCGGTCTCCTACTGTTTGAGAGGACACCGTGTCATCAGAAAAGGGCAACAGTATATTATGAATAGATCTTTTAAGAAGAGTGGAGGTGAAATTGTGGGTTCTCTGGCCCCTGAGGACAATGGCTGTAGCATAGGTGATTTCAATTTGACATGGGCTACGTCACCCAGTGCACCCCAGTACAACCGGTAGGAATTCAGTGATATTTATAACACAGAATCAGACATGGAGACTCTTTCTAAAAGACACATGGGCTTATTTACTAACATAGCGGCTCAACTGAAATGACCCGATTGGCTGCTTTTAATACAAATACTAATAACTGCATTTGAGCAATTATGTTAGTAAATTAAACCTGCAGTAGTTCTATTGTTTACACCATAGCGAGGAAAGACATTTTCGAAGAACAGAAAAAGCTGCATTTTTTCAAAATATACTGTATATTTTTCTTAAAGGGAAACTGTTGCCAAAATGAAAATTTAATGGAGGCTTCATCATACGGAGATGAGAAACTTTCTAAATGCAATTAATTAGAAGAGAAACGGATGCTGAGAGAGGGATAGTGAACATAAACTTGATTATTTCATAAATGGTACAGAATTTTTAGTTGATTGTATTTAGAAAGTTTCTCGTTTCAGTATGAGGAAGCTTATATGGAATTTTCATTTTGGTGATGGTTCCCCTTTAGATGAAAAGTCACACAGTACTGTTTAAGTCTGTGTAAAAAAAAGTGGGATATATAAGAGACGTACCTACATGTAGTGACTGCAAAAATCTCTAGTGCACTTATAAATATAAAAATAATGTCATTATATATACTGGGACAGGGATGACGCCACACTAGAGCTTGAACATACACTGGCACCCAATAAAAGATGAAATAATAAAGCAGTGAGAATAGCTTCCCCGTGACTACAGTGACTACCAAAGACAGAAGGGTGGCTGAGAGGGCAATGTAATTATATTTTAGTGTAATGTGAAAAAACTGGGGAAGGGAAGCTTTTGCTATTCTGCTCAGCTATCTGGGCAATTTTATTTATAGGGTATATGTCCCCTTTAATTAGTACAGGTATGGGATCCGTTATCTGTAAACCCGTTATCCAGAAAATTCTGAATTACAGAAAGGCCATCTCTCATAGACTCCATTTTATTCAAATAATCCAAATTTTTAAAAATGATTTCCTTTTTCTCAAGTACTTGATCCAAACTCAGATATAATTAATCCTTATTGGAAGCAGAACCAGCCTATTGGGTTTATTTCATGTTTTCACAAGACTTAAGGTATGAAGATCCAAAATTCAGAAATATCCAAAAAAAAACATTCTGCATAACCGATTCCATACCTGTACTTCCATACAAACTGTAATTCTGTCTTTGGGAAACAGCCATGAAAGTGAAAGTCCTTAATACCGAAAATAATGACTTAATGATTTGCTATTAGTTAATTACCCCACAGTCAATACGAGAGCACTGTTGGTTAAATAGCAATCTTAGTGGAATGTAAAATATTTAAGGGGGTCATGGGGGGCTAAGATCTGTACAATGTGCAGCACATTTTCAGATGCTTATGAATATTCAATAAAATGCATTTAAAGGCAAATTGTGGAATGTTTATATGAAATATTTACATACATAAGGAGTGAGTTTTACATTAAAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001016688\|frizzled-related protein 2 [Xenopus (Silurana) tropicalis] MAPQSCQSLGKLCSQGQLIVLLCFLTCGSQSMYLDFFGSSSRCTRIPRSMALCYDIGYSEMRIPNLLEHDTMAEVIQQSSSWLPLLARECHPDARIFLCSLFAPICLDRYIYPCRSLCEAVRGSCAPIMACYGYPWPEILRCDKFPEDHGMCISPITNGTGSTRRTVPRASCRDCELEEASTAKEILDTFCDNDFVAKVRITKKNITSANLYDFDLDSKLEILKHGSLPKTDVLPRLQQWLDLDATCVQNIMRGTRTGIYVIGGEVQEDKVVVNNAYAWQKKNKNLQFAVRKWKNHKCRP	Refseq >NP_001082025\|frizzled-related protein 2 precursor [Xenopus laevis] MAPQLCQSLGKPLIVLLCFLACGSQSMYLDFFGSSSRCMRIPKSMALCYDIGYSEMRIPNLLEHETMAEAIQQSSSWLPLLARECHPDARIFLCSLFAPICFDRYIFPCRSLCEAVRSSCAPIMACYGYPWPEILKCDKFPEDHGMCISTITNDTGSTRRTVPRASCRDCELEEGSTSKEILDTFCHNDFVAKVRITKKNITSANLYDFDLDSKLEILKHGSLPKTDVLPRLQQWLDLDATCVQNIMRGTRTGVYVICAEVQEGKVVVNNAYAWQKKNKNLHFAVRKWKNHKCRP

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.76420 [+] Str.36177 Str.27074	Xl.619 [+] Xl.82715 Xl.83522
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		31 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human
mouse
zebrafish

Publications
First:		The cortex of Xenopus laevis embryos: regional differences in composition and biological activity. [Proc Natl Acad Sci U S A 1971]
Most recent:		Gastrulation and pre-gastrulation morphogenesis, inductions, and gene expression: similarities and dissimilarities between urodelean and anuran embryos. [Dev Biol 2012]
		View All Papers 5 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		transmembrane receptor activity
Biological:		multicellular organismal development
Cellular Component:		membrane
EC:
KOG:		[T] Smoothened and related G-protein-coupled receptors

Reagents		tropicalis	laevis
Clones		EXRC - 1 clone(s)	EXRC - 4 clone(s)
		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.27074.1.S1_at [+] Str.36177.1.A1_at	Xl.619.1.S1_at [+] Xl.619.1.S2_at
Affymetrix 2.0			Xl2.619.1.S2_at [+] Xl2.619.1.S1_at Xl2.53605.3.A1_at

Symbol legend[+]