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Summary Expression Gene Literature (25) GO Terms (5) Nucleotides (607) Proteins (23) Interactants (482) Wiki
XB-GENEPAGE- 919630

Gene Symbol: skp1

Gene Name: S-phase kinase-associated protein 1

Synonyms: skp1a
Add Xenopus synonyms , Nomenclature history


Gene Function: ubiquitin ligase component

Protein Function:
Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcriptio...[+]


Interactants: YYY

OMIM Disease Associations:
 
Xenbase Gene ID XB-GENE-919631 XB-GENE-919643 XB-GENE-17344373
Gene Symbol skp1 skp1.L skp1.S
Chromosome Chr03 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq TrEMBL Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.50335 [+] Xl.57174 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 52 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine skp1 skp1.L skp1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards SKP1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Skp1a MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN skp1 ZFIN Ensembl
chicken
GEISHA SKP1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin. [Oncogene 1999]
Most recent: High variability of expression profiles of homeologous genes for Wnt, Hh, Notch, and Hippo signaling pathways in Xenopus laevis. [Dev Biol 2017]
View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 2 terms 4 terms 0 term
EC
PANTHER skp1
KEGG Pathways K03094 K03094
KOG [O] SCF ubiquitin ligase, Skp1 component
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Affymetrix 1.0 Str.21542.1.S1_at [+] Xl.20950.1.S2_at
Affymetrix 2.0 Xl2.20950.2.S1_a_at [+]

Symbol legend[+]

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