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XB-GENEPAGE-
919630
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Gene Symbol: skp1
Gene Name: S-phase kinase-associated protein 1 Synonyms: skp1a Add Xenopus synonyms , Nomenclature history Gene Function: ubiquitin ligase component Protein Function  :
Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcriptio...[+]
Interactants: Loading ... 
OMIM Disease Associations: |
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| Xenbase Gene ID | XB-GENE-919631 | XB-GENE-919643 | XB-GENE-17344373 | ||||
| Gene Symbol | skp1 | skp1.L | skp1.S | ||||
| Chromosome | Chr03 | chr3L | chr3S | ||||
| Molecules | tropicalis | laevis.L | laevis.S | ||||
| Gene |
Genomic sequence
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Genomic sequence
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Genomic sequence
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| CDS |
Gene model
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Entrez Gene
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Entrez Gene
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| mRNA |
Refseq
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Refseq
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| Protein
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Refseq
TrEMBL
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Refseq
Swiss-Prot
TrEMBL
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| Genomic | tropicalis | laevis.L | laevis.S | ||||
| Genome Browser |
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| Links |
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| Genomic Synteny | Genomicus | ||||||
| Expression | tropicalis | laevis.L | laevis.S | ||||
| Ensembl | Ensembl | ||||||
| UniGene | Str.50335 [+] | Xl.57174 [+] | |||||
| RNA-Seq profile | Stage profile: |
Stage profile:
Tissue heatmap:
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| Experimental regulation |
Regulation heatmap:
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| Images | 52 expression image(s) for tropicalis and laevis | ||||||
| Data Mining | tropicalis | laevis.L | laevis.S | ||||
| XenMine | skp1 | skp1.L | skp1.S | ||||
| Phenotype | tropicalis | laevis.L | laevis.S | ||||
| Smith Morpholino Screen | |||||||
| Orthology |
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| human |
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| mouse |
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| zebrafish |
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| chicken |
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| fruit fly |
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| worm |
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| Publications | |||||||
| First: | The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin. [Oncogene 1999] | ||||||
| Most recent: |
High variability of expression profiles of homeologous genes for Wnt, Hh, Notch, and Hippo signaling pathways in Xenopus laevis. [Dev Biol 2017]
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| View All Papers | |||||||
| Functional Ontologies | tropicalis | laevis.L | laevis.S | ||||
| GO | 2 terms | 4 terms | 0 term | ||||
| PANTHER | skp1 | ||||||
| KEGG Pathways | K03094 | K03094 | |||||
| KOG |
[O] SCF ubiquitin ligase, Skp1 component
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| Reagents | tropicalis | laevis.L | laevis.S | ||||
| CRISPR / TALEN | CRISPR tools | CRISPR tools | CRISPR tools | ||||
| Clones | |||||||
| GE Dharmacon | GE Dharmacon | GE Dharmacon | |||||
| Source BioScience | Source BioScience | ||||||
| Affymetrix 1.0 | Str.21542.1.S1_at [+] | Xl.20950.1.S2_at | |||||
| Affymetrix 2.0 | Xl2.20950.2.S1_a_at [+] | ||||||
Symbol legend[+]
