|
XB-GENEPAGE-
919630
Gene Symbol: skp1
Gene Name: S-phase kinase-associated protein 1 Synonyms: skp1a Add Xenopus synonyms , Nomenclature history Gene Function: ubiquitin ligase component Protein Function ![]()
Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcriptio...[+]
Interactants: Loading ... ![]() OMIM Disease Associations: |
|
Xenbase Gene ID | XB-GENE-919631 | XB-GENE-919643 | XB-GENE-17344373 | ||||
Gene Symbol | skp1 | skp1.L | skp1.S | ||||
Chromosome | Chr03 | chr3L | chr3S | ||||
Molecules | tropicalis | laevis.L | laevis.S | ||||
Gene |
Genomic sequence
![]() |
Genomic sequence
![]() |
Genomic sequence
![]() |
||||
CDS |
Gene model
![]() |
||||||
Entrez Gene
|
Entrez Gene
|
||||||
mRNA |
Refseq
![]() ![]() |
Refseq
![]() ![]() |
|||||
Protein
![]() |
Refseq
![]() ![]() |
Refseq
![]() ![]() |
|||||
Genomic | tropicalis | laevis.L | laevis.S | ||||
Genome Browser |
|
||||||
Links |
|
||||||
Genomic Synteny | Genomicus | ||||||
Expression | tropicalis | laevis.L | laevis.S | ||||
Ensembl | Ensembl | ||||||
UniGene | Str.50335 [+] | Xl.57174 [+] | |||||
RNA-Seq profile | Stage profile:![]() |
Stage profile:![]() ![]() |
|||||
Experimental regulation |
Regulation heatmap:![]() |
||||||
Images | 52 expression image(s) for tropicalis and laevis | ||||||
Data Mining | tropicalis | laevis.L | laevis.S | ||||
XenMine | skp1 | skp1.L | skp1.S | ||||
Phenotype | tropicalis | laevis.L | laevis.S | ||||
Smith Morpholino Screen | |||||||
Orthology |
|
||||||
human |
|
||||||
mouse |
|
||||||
zebrafish |
|
||||||
chicken |
|
||||||
fruit fly |
|
||||||
worm |
|
||||||
Publications | |||||||
First: | The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin. [Oncogene 1999] | ||||||
Most recent: |
High variability of expression profiles of homeologous genes for Wnt, Hh, Notch, and Hippo signaling pathways in Xenopus laevis. [Dev Biol 2017]![]() |
||||||
View All Papers | |||||||
Functional Ontologies | tropicalis | laevis.L | laevis.S | ||||
GO | 2 terms | 4 terms | 0 term | ||||
PANTHER | skp1 | ||||||
KEGG Pathways | K03094 | K03094 | |||||
KOG |
[O] SCF ubiquitin ligase, Skp1 component
|
||||||
Reagents | tropicalis | laevis.L | laevis.S | ||||
CRISPR / TALEN | CRISPR tools | CRISPR tools | CRISPR tools | ||||
Clones | |||||||
GE Dharmacon | GE Dharmacon | GE Dharmacon | |||||
Source BioScience | Source BioScience | ||||||
Affymetrix 1.0 | Str.21542.1.S1_at [+] | Xl.20950.1.S2_at | |||||
Affymetrix 2.0 | Xl2.20950.2.S1_a_at [+] |
Symbol legend[+]