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Summary Expression Gene Literature (8) GO Terms (23) Nucleotides (74) Proteins (35) Interactants (247) Wiki
XB-GENEPAGE-919871
Gene Symbol:
intu

Gene Name:
inturned planar cell polarity protein

Synonyms:
pdzd6 , int , inturned , PDZ domain containing 6 , Xint ( Add synonyms , Nomenclature history )

Gene Function:
protein binding

Protein Function :
Plays a role in the definition of cell polarity via the planar cell polarity (PCP) cascade. Required for ciliogenesis by controlling the organization of the apical actin cytoskeleton and the positionin...[+]


InterPro :
PDZ 6 , PDZ , PDZ sf , INTU

Interactants:
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Diseases: 


Disease Ontology:
orofaciodigital syndrome XVII

OMIM:
OROFACIODIGITAL SYNDROME XVII; OFD17 [+]

External Links:
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Xenbase Gene ID XB-GENE-919872 XB-GENE-17332487 XB-GENE-919877
Gene Symbol intu intu.L intu.S
Chromosome Chr1 chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 100495950
734193
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine intu intu.L intu.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards INTU OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Intu MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Intu Ensembl
zebrafish
intu Ensembl
chicken
GEISHA INTU Ensembl
fruit fly
worm
Publications
First Isolation of the Xenopus homolog of int-1/wingless and expression during neurula stages of early development., Nucleic Acids Res 1989  
Most Recent The ciliopathy-associated CPLANE proteins direct basal body recruitment of intraflagellar transport machinery., Nat Genet 2016                                
All View All Papers 3 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 17 terms 0 term 14 terms
PANTHER intu
KEGG Pathways K22862 K22862
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks intu
Morpholinos (on-target & off-target) intu MO2 , intu MO1
Clones EXRC Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info