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Summary Expression Gene Literature (64) GO Terms (12) Nucleotides (134) Proteins (25) Interactants (806) Wiki
XB-GENEPAGE- 920500

Gene Symbol: ventx1.1

Gene Name: VENT homeobox 1, gene 1

Synonyms: PV.1 , posterior-ventral 1 , Xvent-1b , ventx1.1-a , ventx1.1-b
Add Xenopus synonyms , Nomenclature history


Gene Function: homeodomain transcription factor

Protein Function:
Transcriptional repressor. Acts in a ventral signaling pathway downstream of bmp4, which suppresses dorsal mesoderm formation and leads to both ventral mesoderm and ventral ectoderm formation. Acts in ...[+]


Interactants: YYY

OMIM Disease Associations:
 
Xenbase Gene ID XB-GENE-920501 XB-GENE-920512 XB-GENE-6464310
Gene Symbol ventx1.1 ventx1.1.L ventx1.1.S
Chromosome scaffold_7 chr7L chr7S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq TrEMBL Refseq Swiss-Prot Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v7.1 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.43047 [+] Xl.1420 [+] Xl.79762
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 19 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine ventx1.1 ventx1.1.L ventx1.1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM, MalaCards, KEGG Disease, DECIPHER Protein Atlas, Allen Brain Atlas
mouse
MGI, IMPC Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN
chicken
fruit fly
worm
WORMBASE
Publications
First: A novel homeobox gene PV.1 mediates induction of ventral mesoderm in Xenopus embryos. [Proc Natl Acad Sci U S A 1996]
Most recent: Lineage commitment of embryonic cells involves MEK1-dependent clearance of pluripotency regulator Ventx2. [Elife 2017]
View All Papers 18 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 3 terms 10 terms 8 terms
EC
PANTHER ventx1.1
KEGG Pathways
KOG [K] Transcription factor tinman/NKX2-3, contains HOX domain
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Morpholino ventx1.1 MO1 , ventx1.1 MO2 , ventx1.1 MO3 ventx1.1 MO1 , ventx1.1 MO2 , ventx1.1 MO3 ventx1.1 MO1 , ventx1.1 MO2 , ventx1.1 MO3
Affymetrix 1.0 Str.43047.1.S1_at [+] Xl.203.1.S1_at
Affymetrix 2.0 Xl2.203.1.S1_at [+]

Symbol legend[+]

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