insr Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (50)

Nucleotides (56)

Interactants (71)

XB-GENEPAGE-920732

Gene Symbol: insr [provisional] Gene Name: insulin receptor [provisional] Synonyms: Xe-InsR, insulin receptor, hhf5, cd220 Add Xenopus synonyms Gene Function: growth factor receptor, contains protein kinase domain Interactants: ins(50) , irs1(10) , igf1(8) , rps6ka3(8) , mapk1(6) , grb2(4) , cdk1(3) View All	1/2

XB-GENE-920733

XB-GENE-920741

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		NCBI Nucleotide >XM_002934379\|PREDICTED: Xenopus (Silurana) tropicalis insulin receptor-like (LOC100492718), mRNA ATGGGACAGGGTGTATTGTGGGGTGAGGGGCACCCCAATAATAACCCCAAGAGCAAGGTGGGCTGGAAGTCCATTGCGGGAATATTCATCATTTTTATGCTCATTCTGTGCGACCAAAACGACGGGAAAATTTGCCCCAGTATGGATATCCGGAATAACATTAGTCAGTTCAGTATGCTTGAGGACTGTACAGTAATTGAAGGTCACCTTCAGATCTTGCTTATGTTCACCAGCAAACCAGAGAACTTCCGAGGGTTGAGATTTCCCAAGCTCACCATGATCACAGATTACCTCCTGCTTTTCCGGGTCTATGGCTTAGAAAGTCTAAAGGACCTTTTTCCCAACCTCACAGTTATCCGTGGTACTCACCTCTTTTTCAACTATGCCCTAGTCATCTTTGAGATGGTCCACCTGAAGGAGATTGGGCTCTACAACCTAATGAACATTACTAGGGGGTCTGTTAGAATTGAGAAAAATAATGAACTTTGTTATCTTTCTACGATTGATTGGTCCATAATTCTTGACTCTGTGGAGGATAACTACATTGAACTCAACAGGGACAATAAAGAGGAGTGTGGAGATGTTTGTCCTGGTGCAGGAAAAGGCAAGAGCAAATGCAAACAGATAGTAGTCAATGGAGCATTCATTGAGCGCTGCTGGACACAGGACCACTGTCAAACAGTGTGCCCTTCAGAATGCAAGGGAAGTGGTTGTTTGCCAGATGGACAGTGCTGCCACTCAGAGTGCCTTGGAAGCTGCAGAAAGCCTAATGATCCAACTGAGTGTACCGCCTGCCGGCATTACCAGTATCAGGGTGTGTGTATCAGTGCATGTCCCGAGGGGTCTTACCGGTTCCAGGGTTGGCGGTGCATTGACTTCAATACCTGTCAAGAAATGCACAACCGGTGCCCAAATAAGGAAAATTCCTGTCCTCCTTATGTCATCCACAAGGGAGAGTGCATGCCAGATTGCCCATCAGGCTATATTGCCAACTCAACTACCCGTACTTGTACACCATGCGCAGGACCTTGCCCCAAAGTTTGCACCATCTACCAAAGTGTCAAGACCATAGACTCTGTGACATCTGCTCAAGAATTAAGAGGGTGCACAGTGGTCAACGGTAGTCTTATCATCAACATCCGTGGAGGCAGTGAGGACAATTTACTGAACTTTAACTTTATAAGGACATCGCATGATATGGTGCTGTTAAAGTGGGATCCTTACTGGCCCCCTGATTACAGAGACCTCTTGGGCTTCATGGTGCATTATAAGGAAGCACCCTACCAGAATGTCACAGAATTTGATGGTCAGGATGCTTGTGGTTCCAATAGTTGGACAGTGGTAGATATGGATGCCCCAGAACGAAGTGCTGATGGCAAGACTCTATCTCCGGGATGTTTGCTCCGTAACCTGAAACCATGGACTCAGTATGCAGTGTTTGTTAAAACACTGGTATCCGGATCAGATGAAGGAAGAACTTATGGTGCAAAAAGCAAAATTATCTATATTCGTACCAATGAAACCATCCCCTCTGTTCCTCTGGATCCTTTCTCTGTGTCCAACTCAACCTCTCAGATTATTCTAAAATGGAAACCACCTTCTGAGCCCAATGGAAATGTCACTCACTACCTTGTGTACTGGCAAGAACAACCTGAAGACAGTGAACTTTATGAGCTGGATTACTGCAATAAAGGTCTTAAGTTGCCTTCCAGAACTTGGACTCCTCCCTCGGATATTGAGGAAAATGGAAATATAAATCAGACAGACCAACCTTCATCCAAGTGCTGTCCCTGTCCCAAAACTGATTTCCAAATCCAGAAAGAACAGGATGAATCAGCATTCAGAAAAACATTTGAAAATTATCTACATAATGAAGTTTTTATACCTAGACCTGTTCGAAAACGGCGTGAACTATTTGGAGTAGCCAATGGAACTCTGCCAGACCCAGTGACAGCCCCTTCTCTCTTCAATGCCTCCTCCACCCGTGCTCCGGATGAAACAGAGCCAAAGATATATTCACAGAAAGTTTGGTTTAAGGAGTCTCTAATGGTCACTGGCTTAAAGCATTTTACTGGTTACCGCATTGAGATTCATGCCTGCAACCACGAACTCTCCATGGGATGTAGCGTGGCAGCATATGTTAGTGCAAGGACAATGCCAGAGGCCACTGCCGACAATGTTGTGGGACCCATCACCTATGAGTATATTGAACCTAATATAATCCATTTAAAATGGCAAGAACCAAAAGATCCAAATGGGCTAATAGTTTTGTATGAGGTGCATTACTCCCGAGTTGGGGGCACAGAGGAAGTGATTAGCTGCGTGTCACAGAAGCAGTATAGCACAGACAAAGGGGCAAAACTCAGGGTATTAACCCCAGGGAATTACAGTGTAAAGATCCGTGCAACCTCCCTGGCAGGCAATGGATCATGGACAGAACCAGCCTACTTCCAAGTGCCAGACCACCCTCACAGCAGCATAGTGAAAATCGTCACTGGTCCAGTAATTGCAGTCATTCTTCTGCTTTTTGTCCTGGTTTACTGTGTTATTCAGAAGAAAAAAGATGCAGAAGGCCCAGTTGGACCACTCTACGCCTCCTCTAATCCTGAATATCTTAGTGCAAGTGAAGTCTACATCCCTGACGAATGGGAGGTACCACGTGATAAAATCAGCTTACTGCGAGAATTGGGCCAGGGCTCATTTGGAATGGTGTACGAGGGTATTGCCAAAGATATTATCAAGGGAGAGCCAGAAGTTCGTGTTGCTGTGAAAACTGTGAATGAGTCTGCAAGCCTTCGAGAGAGGATAGAATTCCTAAATGAGGCTTCTGTCATGAAGGCATTTAGCTGCCACCATGTGGTCCGTCTGCTTGGTGTGGTGTCCAAAGGTCAGCCAACACTTGTCATCATGGAGTTAATGACGCATGGGGATCTCAAAAGTTACCTGCGCTCACTGCGACCTGATGCAGAGAATAACCCAGGACGTCCTGCTCCTACCCTTAAAGAAATGATCCAGATGGCAGCGGAAATTTCAGATGGCATGGCATATCTCAATGCTAAAAAGTTTGTACACAGGGATCTGGCTGCTAGGAACTGCATGGTTGCTGAAGATTATACTGTGAAAATTGGAGATTTTGGAATGACACGAGATATCTATGAGACAGATTATTACCGAAAAGGGGGAAAGGGGCTGCTGCCTGTTAGATGGATGTCCCCTGAATCACTGAAAGATGGAGTGTTCACAACTTTCTCAGATGTCTGGTCCTTTGGAGTTGTTTTATGGGAAATAACGAGTTTGGCAGAACAGCCATATCAGGGACTTTCTAATGAGCAGGTCCTGAAGTTTGTCATGGATGGAGGTTCACTTGACCAACCGGAGAATTGCCCTCCAAGGCTGCATAGTCTGATGCAGATGTGCTGGCAGTATAACCCCAAGATGCGGCCTACCTTCTTGGAGATTATCGACATGTTAAAAGATGACCTGCATCTTAGTTTTCAGGAAGTCTCATTCTACTACAGTGACGAGAACAAGCCACCTGAAACAGATGATTTGGAAATTGATTTTGAAAATATGGAGAGCACACCCCTGGACCCTTCTTCCTGTTCTTTACGGGATCAGTCGAATCGGGGGAACATTTATGAAGAACACATCCCCTACACCCATATGAATGGTGGCAGAAAAAATGGACGTATACTGTCTTTGCCACGGTCCAGCCCATCCTAACATATAATACTCTGTAAAATTCTAAGCATCTTAACCCTCCGTCAAATCTCAGGACAGAACAATTCCCATGGCTAGAACATCAAACCAACAACACCCTCTTCAGGTTTTGAATGTCTCATTATCTAACTGGGTTCATGAATTTATTGTCATGTTTGTTTTGTTTTCTGACAGTTTTGACAGGCTGACTATAGGGCAAAACTGTGAACGGACATACAAGAGGTTGGTCTCCAATCTACACTAGAATGCCTATTTATTTTCAGTGGCTGTTAACCAGCAGTTTTTCAGTGTGGCATGGATATGGGAGGAAGAAGAGGAAATGCATCCATATGCAAATTACCAGAAAAGCACATGTGCGCACCAAAAAAAGATGAAAAATCCCTGCTGGTTCAACATGATATTTTTTATCTGTGGCGGATTAGCTTTTGGTGGATCTTGGCCTCCTCCTATTGGTTGACCAAGCCAAAGTGAAGTTTGGATGTTCATTGACCTCGGAGTATTTTAATCCTGCTGCTTTCTCTGAGAATGGGTGGAAAAATAAGACTAAACTTGGGTAATAAGAGAGTCTGGGAATGTAGGACAAGCCAGATGTACCTCACAGGGGGAATATCTTAACTCAGTGATAATCAGAAGCCCTCTCTGTCCCATTCACCTCTTCATTAACATGACCTGCTGAGAAGTTTTACCTACAGTAAAGAAGCCTTTTGCTATACTTAAGTGCAAAAACCGGGCTTCTGAGTTCGACCCCTCCTCCTCTCTGTTAAGTGGTGTGGTTTTCCAGCTTTGTTTGAGGCATGGAGGCCATAAAGGACATGAAAACTAGCTGCCTTTAAGGCCAACACAGATTTGGGGTCGGTTTTATGTTTGTTTGTCAGGTATGTTATTGATCAGACCAAAAATGGAGGAATTTCTCAACATCTTTCTCCTCCTACCTATTCAATCTCAAGATCATTGTCTATAGTTTTAACTTTTGTTTCGTTCTATATTGTACCTTTATGGAGTCACTGGGTTGATTTAGTTTAACTTCATTGAGAGGCAGTCATCGTGCCATTGAAACTCTGTTTTACAAAACCCCAACAAACAATAGGCCTCTGCAATATTTCAAGGGTTATGTAGGTAAGCTAAATCCTTTAATAACAGAAAGACCATGCTGCAAGCTTTTCTGACAGCAATGGGGTTAACCATTTGCTAGTAGCTTCTGTGGTTAATACAAAAGCTTGTTTCTGAGATTAGGACTCCTGCCTGGTGTGCATAATATTACAACTAAATATATAGCAGTTGCTTCTTTGCTATATATATATATATATAGCAGGCAGTACATCATGGTTGAATGC	Refseq >NM_001088233\|Xenopus laevis insulin receptor (insr), mRNA CTGAGCTGTCACAATCACAGCATTAAATAAAGACCTTACTTAGGGACATTGTTTTTTGTTNTTAATTGGATTTTTAATTATTTTTTTTTTACCTTTTGTCCTTGCCAATTTTAGTAAGCCAGACTTCCCCCCTATAGCTGCTGCTGGGGAAATACTACTACAAGGTGGGGGAGCTGAGCTATAGGCATGGGACAGGGTGTATTGAGGGGTGAGGGGCACCCCAATAATAACCCCAATAGCAAGGTGGGCTGGAAGTCACTTGTGGGAATAATCACCATTTTTATGCTTATTCTGTGCGACCAAAGCGACGGCAAAATTTGCTACAGTATGGATATCCGAAATAATATAAGTCAGTTCAGTATGCTTGAGGACTGTACAGTAATTGAGGGTCACCTTCAGATCTTGCTTATGTTCACCAGCAAACCAGAGAACTTCCGAGGGTTGAGATTTCCCAAGCTCACGACGATCACAGATTACCTCCTGCTCTTTCGGGTCTACGGCTTAGAAAGTCTAAAGGACCTTTTCCCCAACCTTACAGTTATCCGTGGTACTCGCCTCTTTTTCAACTATGCCTTAGTGATTTTTGAGATGGTCCACNTAAAGGAGATTGGGCTCTACAACCTAATGAACATTACTAGAGGGTCTGTTCGAATTGAGAAAAATAATGAGCTTTGTTATCTTTCTACAATTGATTGGTCCATAATTCTTGACTCTGTGGAGGATAATTACATTGAGCTCAACAGAGACAATAAAGAGGAGTGTGGAGATGTTTGTCCTGGCACAGTAAAAGGCAAGAGTAAGTGCAAACATACGTTAGTCAACGGAGCATTGGTTGAGCGCTGCTGGACACAGGACCACTGTCAAAAAGTGTGCCCTTCAGATTGCAAGGGGAGTGGTTGTTTGCCAGATGGACAGTGCTGCCACCCAGAGTGCCTAGGAAGCTGCCGCAAGCCTAATGATCCATCTGAGTGTACCGCCTGCCGGCATTTCCAGAATGAGGGTGTATGTGTCACTGCATGTCCCAAAGGGTCTTACCAGTTCCAGGGTTGGCGCTGCATTGACTTCAATACCTGTCAAGAATTGAACAGCAGGTGCCAAAATTCACGGGATAACTCCTGTCCTCCATACGTCATCCACAAGGGAGAGTGCATGCCAGATTGCCCATCAGGCTATATTGCCAACTCAACCACCCGTACTTGTACACCATGCGCAGGACCTTGCCCCAAAGTTTGCACCATCTTCCAGAATGTCAAGACCATTGACTCTGTGACATCTGCTCAAGAATTAAGAGGGTGCACAGTAATCAACGGTAGTCTTATCATCAACCTCCGTGGAGGCAATAATATCGCAACAGAATTAGAAGCCAACCTGGGACTCATAGAAGAGATTTCTGGATATCTTAAGATCAGAAGATCATATGCATTGGTGTCATTGTCATTCTTCCGCAAGTTGCGTTTAATTAGGGGAGAAGTGTTGGAAGCAGGCAACTATTCTTTCTATGCTTTGGATAATCCCAGCCTACGCCAGCTGTGGGACTGGCATAAGCACAACCTGACCATCATACATGGCAAGCTCTTCTTTCATCACAATCCACGACTATGTCTATCGCAAATTCACCAAATGGAGGAGGTTACAGGAACAAAGGGCCGGCAGGACAAAAATGACATTGCCACAAAGACCAATGGAGACCAGGCATCCTGCGAGGACAATTTGCTGACCTTTAACTTTATAAAGACATCACATGATATGGTGCTGTTAAGGTGGGATGCATACTGGCCCCCTGATTACAGAGACCTCTTGGGCTTCATGGTACATTATAAGGAAGCCCCCTTCCAGAATGTGACAGAATTTGATGGTCAGGATGCTTGTGGTTCCAATAGTTGGACAGTGGTAGATATGGATGCCCCAGAACGAAGTGCTGATGGCAAGACTCAGTCTCCAGGATGTTTGCTCCGTAGCCTGAAACCATGGACTCAGTATGCAGTATTTGTTAAAACACTGGTGTCTGGATCAGATGAAGGGAGAACTTATGGCGCAAAAAGCAAAATTATCTACATTCGTACTAATGAAACCATCCCCTCAGTCCCTTTGGATCCTTTCTCTGTGTCCAACTCAACCTCTCAGATTATCCTGAAATGGAAACCACCTTCTGAGCCCAATGGAAATGTCACCCACTACCTTGTGTACTGGCAAGAGCAGCCTGAAGACAGTGATCTTTATGAAGTGGATTACTGCAATAAAGGGCTTAAGTTGCCTTCTAGAACATGGACTCCTCCCACAGAGATTGATGAAAATGGAAATGAAAATCAGACAGAACATACTTCAGTCAACAAGTGCTGTCCCTGTCCCAAAACTGAGTTCCAGATCCAGAAAGAACAGGATGAGTCAGCATTCAGAAAAACATTTGAAAATTATCTACACAATGAAGTATTTATTCCTAGACCTGTTAGGAAACGGCGTGACCTCTTTGGAGTAGCCAATGGAACTTTGCCAGACCCAGTGACAGCCCCTCCTCTGTTCAATGTCTCTTCCACCCGTGCTCCTGATGAACCAGAGCCCAAGATATACTCACAGAAAGTTTGGTTCAAGGAGTCTGTATTAATCTCTGGCTTAAAGCATTTCACTGGTTACCGCATTGAAATCCATGCATGCAATCACGAACTCTCCATGGGATGCAGCGTGGCAGCATATGTTAATGCAAGGACTATGCCAGAGGCCACGGCTGACAAAGTTGTTGGACCCATCACCTATGAGTATGTTGAACCTAATATAATTCACTTAAAATGGCAAGAACCAAAAGATCCAAATGGGCTGATAGTCTTGTATGAGGTGCATTACTCCAGAGTTGGGGGCATAGAGGAAGTGATCACCTGTGTGTCACAGAAGCAGTATAACACAGACAAAGGGGGAAAACTCAGGGTATTAACACCAGGGAATTACAGTGTTAAGATCCGTGCAACCTCCTTGGCAGGCAATGGATCATGGACAGAACAGGCCTACTTCCAAGTGCCAGACCACCCTCACAGCAACATAGTAAAGATCATCACTGGTCCAATAATTGCAGTCTTTCTTCTCCTTATTGTCCTGGTGTACTGCGTTGTTCAGAAGAAAAAAGATGCAGAAGGTCCAGCTGGACCACTGTACACCTCCTCTAACCCTGAATATCTGAGTGCAAGTGAAGTCTACATCCCTGATGAATGGGAGGTACCACGTGATAAGATCAATTTGCTTCGAGAATTGGGCCAGGGCTCATTTGGAATGGTGTATGAGGGAATCGCCAAAGATATTATCAAGGGAGAGCCGGAAGTTCGTGTAGCTGTGAAAACTGTGAATGAATCTGCAAGCCTCCGAGAGAGGATAGAATTCCTAAATGAGGCTTCTGTCATGAAGGCATTCAACTGCCACCATGTGGTCCGTCTGCTTGGTGTGGTGTCCAAGGGTCAGCCAACACTCGTCATCATGGAGTTAATGGCGCATGGGGATCTCAAGAGTTACCTGCGCTCACTGCGACCTGATGCAGAGAATAACCCAGGACGTCTTGCTCCTACCCTTAAAGAAATTATCCAGATGGCAGCAGAGATTTCAGACGGCATGGCATATCTTAATGCTAAAAAGTTTGTGCACAGGGATCTGGCTGCTAGGAACTGCATGGTTGCTGACGATTATGCTGTGAAAATTGGTGATTTTGGAATGACACGAGATATCTATGAGACAGATTATTACCGGAAAGGGGGAAAAGGACTCCTGCCTGTAAGGTGGATGTCCCCGGAATCCCTAAAAGATGGGGTTTTCACGGCTTTCTCAGATGTCTGGTCCTTTGGAGTTGTATTATGGGAGATAACAAGTTTGGCGGAACAGCCCTATCAGGGACTTTCTAATGAGCAGGTCCTAAAATTTGTCATGGATGGAGGTTCACTTGACCATCCAGAGAATTGCCCCCCAAGGCTGCATAGTCTGATGCAGATGTGCTGGCAGTATAACCCCAAGATGCGCCCGACCTTCTTGGAGATTATCGACATGCTAAAAGATGACCTACGTCCTAGTTTTCAGGATGTCTCCTTCTACTATAGTGACGAAAACAAGCCACCTGAAACAGATGATTTGGAGATTGATTTTGAGAATATGGAGAGCACACCCCTGGACCCTTCTTCCTGTTCATTACGGGATCAGTCGAGTCGGACGAACATCTATGAAGAACACATCCCCTACACCCACATGAATGGTGGCAGAAAAAATGGACGAATACTGTCTTTGCCACGATCCAGCCCATCCTAACATATAATGTTCTAAGATTCTAAGCATCTTAACCCTCCGTCAATTCTCAGGACAGAACAATGCCCATGGCTAGAACATCAAACCAACAACACCCTCTTCAGGTTTTGAATTGTCTCATTGTCTAACTGGGTTCATGAATTTATTGTCATGTTTATTTGTTTTGTTNTCTGACAGTTTTGANAGGCTGAATATAGGGCNAAACTGTGAATGGACNAACNGGAGGATGGTCTCCNATCTACACTANAATG
Protein		NCBI Protein >XP_002934425\|PREDICTED: insulin receptor-like [Xenopus (Silurana) tropicalis] MGQGVLWGEGHPNNNPKSKVGWKSIAGIFIIFMLILCDQNDGKICPSMDIRNNISQFSMLEDCTVIEGHLQILLMFTSKPENFRGLRFPKLTMITDYLLLFRVYGLESLKDLFPNLTVIRGTHLFFNYALVIFEMVHLKEIGLYNLMNITRGSVRIEKNNELCYLSTIDWSIILDSVEDNYIELNRDNKEECGDVCPGAGKGKSKCKQIVVNGAFIERCWTQDHCQTVCPSECKGSGCLPDGQCCHSECLGSCRKPNDPTECTACRHYQYQGVCISACPEGSYRFQGWRCIDFNTCQEMHNRCPNKENSCPPYVIHKGECMPDCPSGYIANSTTRTCTPCAGPCPKVCTIYQSVKTIDSVTSAQELRGCTVVNGSLIINIRGGSEDNLLNFNFIRTSHDMVLLKWDPYWPPDYRDLLGFMVHYKEAPYQNVTEFDGQDACGSNSWTVVDMDAPERSADGKTLSPGCLLRNLKPWTQYAVFVKTLVSGSDEGRTYGAKSKIIYIRTNETIPSVPLDPFSVSNSTSQIILKWKPPSEPNGNVTHYLVYWQEQPEDSELYELDYCNKGLKLPSRTWTPPSDIEENGNINQTDQPSSKCCPCPKTDFQIQKEQDESAFRKTFENYLHNEVFIPRPVRKRRELFGVANGTLPDPVTAPSLFNASSTRAPDETEPKIYSQKVWFKESLMVTGLKHFTGYRIEIHACNHELSMGCSVAAYVSARTMPEATADNVVGPITYEYIEPNIIHLKWQEPKDPNGLIVLYEVHYSRVGGTEEVISCVSQKQYSTDKGAKLRVLTPGNYSVKIRATSLAGNGSWTEPAYFQVPDHPHSSIVKIVTGPVIAVILLLFVLVYCVIQKKKDAEGPVGPLYASSNPEYLSASEVYIPDEWEVPRDKISLLRELGQGSFGMVYEGIAKDIIKGEPEVRVAVKTVNESASLRERIEFLNEASVMKAFSCHHVVRLLGVVSKGQPTLVIMELMTHGDLKSYLRSLRPDAENNPGRPAPTLKEMIQMAAEISDGMAYLNAKKFVHRDLAARNCMVAEDYTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTFSDVWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGSLDQPENCPPRLHSLMQMCWQYNPKMRPTFLEIIDMLKDDLHLSFQEVSFYYSDENKPPETDDLEIDFENMESTPLDPSSCSLRDQSNRGNIYEEHIPYTHMNGGRKNGRILSLPRSSPS	Refseq >NP_001081702\|insulin receptor precursor [Xenopus laevis] MGQGVLRGEGHPNNNPNSKVGWKSLVGIITIFMLILCDQSDGKICYSMDIRNNISQFSMLEDCTVIEGHLQILLMFTSKPENFRGLRFPKLTTITDYLLLFRVYGLESLKDLFPNLTVIRGTRLFFNYALVIFEMVHXKEIGLYNLMNITRGSVRIEKNNELCYLSTIDWSIILDSVEDNYIELNRDNKEECGDVCPGTVKGKSKCKHTLVNGALVERCWTQDHCQKVCPSDCKGSGCLPDGQCCHPECLGSCRKPNDPSECTACRHFQNEGVCVTACPKGSYQFQGWRCIDFNTCQELNSRCQNSRDNSCPPYVIHKGECMPDCPSGYIANSTTRTCTPCAGPCPKVCTIFQNVKTIDSVTSAQELRGCTVINGSLIINLRGGNNIATELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGEVLEAGNYSFYALDNPSLRQLWDWHKHNLTIIHGKLFFHHNPRLCLSQIHQMEEVTGTKGRQDKNDIATKTNGDQASCEDNLLTFNFIKTSHDMVLLRWDAYWPPDYRDLLGFMVHYKEAPFQNVTEFDGQDACGSNSWTVVDMDAPERSADGKTQSPGCLLRSLKPWTQYAVFVKTLVSGSDEGRTYGAKSKIIYIRTNETIPSVPLDPFSVSNSTSQIILKWKPPSEPNGNVTHYLVYWQEQPEDSDLYEVDYCNKGLKLPSRTWTPPTEIDENGNENQTEHTSVNKCCPCPKTEFQIQKEQDESAFRKTFENYLHNEVFIPRPVRKRRDLFGVANGTLPDPVTAPPLFNVSSTRAPDEPEPKIYSQKVWFKESVLISGLKHFTGYRIEIHACNHELSMGCSVAAYVNARTMPEATADKVVGPITYEYVEPNIIHLKWQEPKDPNGLIVLYEVHYSRVGGIEEVITCVSQKQYNTDKGGKLRVLTPGNYSVKIRATSLAGNGSWTEQAYFQVPDHPHSNIVKIITGPIIAVFLLLIVLVYCVVQKKKDAEGPAGPLYTSSNPEYLSASEVYIPDEWEVPRDKINLLRELGQGSFGMVYEGIAKDIIKGEPEVRVAVKTVNESASLRERIEFLNEASVMKAFNCHHVVRLLGVVSKGQPTLVIMELMAHGDLKSYLRSLRPDAENNPGRLAPTLKEIIQMAAEISDGMAYLNAKKFVHRDLAARNCMVADDYAVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTAFSDVWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGSLDHPENCPPRLHSLMQMCWQYNPKMRPTFLEIIDMLKDDLRPSFQDVSFYYSDENKPPETDDLEIDFENMESTPLDPSSCSLRDQSSRTNIYEEHIPYTHMNGGRKNGRILSLPRSSPS UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.25795	Xl.201 [+] Xl.72996
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		3 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	INSR	OMIM:610549 OMIM:609968 OMIM:246200 OMIM:262190
mouse		MGI	Insr	All(8) Targeted, knock Out(2) Targeted, other(3) Chemically Induced(3)
zebrafish		ZFIN ZFIN	insrb insra	9 Lines(s) 1 Lines(s)

Publications
First:		Expression of a functional human insulin receptor from a cloned cDNA in Chinese hamster ovary cells. [Proc Natl Acad Sci U S A 1985]
Most recent:		Xenopus laevis insulin receptor substrate IRS-1 is important for eye development. [Dev Dyn 2011]
		View All Papers 2 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		ATP binding epidermal growth factor receptor activity protein kinase activity More[+] protein serine/threonine kinase activity protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity
Biological:		protein amino acid phosphorylation transmembrane receptor protein tyrosine kinase signaling pathway
Cellular Component:		membrane
EC:		now EC:2.7.10.1 and EC:2.7.10.2
KOG:		[T] Insulin/growth factor receptor (contains protein kinase domain)

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.25795.1.A1_at [+] Str.40036.1.S1_at Str.40036.2.S1_at StrEns.2800.1.S1_at	Xl.201.1.S1_at [+] Xl.15511.1.A1_at
Affymetrix 2.0			Xl2.21470.1.S1_at [+] Xl2.21470.1.A1_at Xl2.15511.1.A1_at Xl2.201.1.S1_at

Symbol legend[+]