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Summary Expression Gene Literature (4) GO Terms (22) Nucleotides (82) Proteins (27) Interactants (51) Wiki
Gene Symbol:

Gene Name:
mitogen-activated protein kinase kinase kinase 10

xmlk2 , mlk2 ( Add synonyms , Nomenclature history )

Gene Function:
serine/threonine kinase

Protein Function :
Activates the JUN N-terminal pathway. Essential for pronephros and cement gland development.

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External Links:
Xenbase Gene ID XB-GENE-920944 XB-GENE-920952 XB-GENE-17334773
Gene Symbol map3k10 map3k10.L map3k10.S
Chromosome Chr08 chr8L
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 100488058
mRNA NCBI Nucleotide RefSeq
Protein NCBI Protein RefSeq Swiss-Prot
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine map3k10 map3k10.L map3k10.S
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
HGNC AGR, OMIM:Gene, GeneCards MAP3K10 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
MGI, AGR Map3k10 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
RGD, AGR Map3k10 Ensembl
ZFIN, AGR map3k10 ZFIN Ensembl
fruit fly
First A tissue restricted role for the Xenopus Jun N-terminal kinase kinase kinase MLK2 in cement gland and pronephric tubule differentiation., Dev Biol 2003        
Most Recent A ubiquitin-conjugating enzyme, ube2d3.2, regulates xMLK2 and pronephros formation in Xenopus., Differentiation 2008                    
All View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 14 terms 11 terms 0 term
PANTHER map3k10
KEGG Pathways K04418 K04418
KOG [T] Tyrosine kinase specific for activated (GTP-bound) p21cdc42Hs
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks map3k10
Clones Horizon Source BioScience Horizon Source BioScience

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