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Summary Expression Gene Literature (7) GO Terms (6) Nucleotides (167) Proteins (24) Interactants (39) Wiki
XB-GENEPAGE- 922820

Gene Symbol: dad1

Gene Name: defender against cell death 1

Synonyms: DAD-1
Add Xenopus synonyms , Nomenclature history


Gene Function: negative regulator of programmed cell death

Protein Function:
Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue wit...[+]


Interactants: Loading ...

OMIM Disease Associations:
 
Xenbase Gene ID XB-GENE-922821 XB-GENE-17344095 XB-GENE-922833
Gene Symbol dad1 dad1.L dad1.S
Chromosome Chr01 chr1L Scaffold131
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq TrEMBL TrEMBL Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.10052 Xl.43587
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 7 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine dad1 dad1.L dad1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards DAD1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Dad1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN dad1 ZFIN Ensembl
chicken
GEISHA DAD1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Molecular cloning of a human cDNA encoding a novel protein, DAD1, whose defect causes apoptotic cell death in hamster BHK21 cells. [Mol Cell Biol 1993]
Most recent: Retention of duplicated ITAM-containing transmembrane signaling subunits in the tetraploid amphibian species Xenopus laevis. [Dev Comp Immunol 2015]
View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 5 terms 4 terms 5 terms
EC dolichyl-diphosphooligosaccharideprotein glycotransferase
PANTHER dad1
KEGG Pathways K12668 K12668 K12668
KOG [DO] Defender against cell death protein/oligosaccharyltransferase, epsilon subunit
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
ORF dad1 ORF1
Affymetrix 1.0 Str.10052.1.S1_at Xl.8166.1.S1_at
Affymetrix 2.0 Xl2.43587.1.S1_a_at

Symbol legend[+]

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