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Summary Expression Gene Literature (2) GO Terms (10) Nucleotides (264) Proteins (22) Interactants (258) Wiki
XB-GENEPAGE- 923355

Gene Symbol: sae1

Gene Name: SUMO1 activating enzyme subunit 1

Synonyms: Aos , Aos1p , Sua1p
Add Xenopus synonyms , Nomenclature history


Gene Function: ubiquitin-protein ligase

Protein Function:
The heterodimer acts as an E1 ligase for sumo1, sumo2, and sumo3. It mediates ATP-dependent activation of sumo proteins followed by formation of a thioester bond between a sumo protein and a conserved ...[+]


Interactants: Loading ...

OMIM Disease Associations:
 
Xenbase Gene ID XB-GENE-923356 XB-GENE-923367 XB-GENE-17345580
Gene Symbol sae1 sae1.L sae1.S
Chromosome Chr08 chr8L
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Swiss-Prot Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.7505 Xl.7420
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 0 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine sae1 sae1.L sae1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
SAE1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Sae1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN sae1 ZFIN Ensembl
chicken
GEISHA SAE1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: SUMO2/3 modification of cyclin E contributes to the control of replication origin firing. [Nat Commun 2013]
Most recent: Genome-wide identification of thyroid hormone receptor targets in the remodeling intestine during Xenopus tropicalis metamorphosis. [Sci Rep 2017]
View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 9 terms 5 terms 0 term
EC ubiquitinprotein ligase
PANTHER sae1
KEGG Pathways K10684 K10684
KOG [O] SMT3/SUMO-activating complex, AOS1/RAD31 component
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
ORF sae1 ORF1
Affymetrix 1.0 Str.7505.1.S1_at Xl.7420.1.S1_at [+]
Affymetrix 2.0 Xl2.7420.1.S2_at

Symbol legend[+]

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