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Summary Expression Gene Literature (63) GO Terms (11) Nucleotides (49) Proteins (27) Interactants (287) Wiki
XB-GENEPAGE-943007
Gene Symbol:
bcl2

Gene Name:
B-cell CLL/lymphoma 2

Synonyms:
bcl-2 , xBcl-2 , xbcl2 ( Add synonyms , Nomenclature history )

Gene Function:
regulator of cell death/apoptosis

Protein Function :



Interactants:
Loading ...

Diseases: 


OMIM:
B-CELL CLL/LYMPHOMA 2; BCL2

External Links:
 
Xenbase Gene ID XB-GENE-943008 XB-GENE-17346445 XB-GENE-6251434
Gene Symbol bcl2 bcl2.L bcl2.S
Chromosome Chr6 chr6L chr6S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100485267
108719105
100271914
mRNA NCBI Nucleotide NCBI Nucleotide RefSeq
Protein NCBI Protein TrEMBL NCBI Protein TrEMBL NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine bcl2 bcl2.L bcl2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, BCL2 Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Bcl2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Bcl2 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR bcl2a bcl2b ZFIN Ensembl
chicken
GEISHA BCL2 Ensembl
fruit fly
worm
Publications
First Molecular cloning of a human cDNA encoding a novel protein, DAD1, whose defect causes apoptotic cell death in hamster BHK21 cells., Mol Cell Biol 1993  
Most Recent NEIL1 and NEIL2 DNA glycosylases protect neural crest development against mitochondrial oxidative stress., Elife 2019                                      
All View All Papers 8 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 9 terms 6 terms 6 terms
PANTHER bcl2
KEGG Pathways K02161 K02161 K02161
KOG [T] Anti-apoptotic Bcl-2 family proteins, prevent opening of mitochondrial porin channel
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks bcl2
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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