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Summary Expression Gene Literature (38) GO Terms (33) Nucleotides (105) Proteins (31) Interactants (226) Wiki
XB-GENEPAGE-943035
Gene Symbol:
nbn

Gene Name:
nibrin

Synonyms:
nibrin , nbs , nbs1 ( Add synonyms , Nomenclature history )

Gene Function:
Transcription initiation factor IIF, large subunit (RAP74)

Protein Function :
Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand b...[+]



Interactants:
Loading ...

Diseases: 


Disease Ontology:
aplastic anemia [+]

OMIM:
APLASTIC ANEMIA [+]

External Links:
 
Xenbase Gene ID XB-GENE-943036 XB-GENE-943040 XB-GENE-17337690
Gene Symbol nbn nbn.L nbn.S
Chromosome Chr06 chr6L
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 733826
403373
mRNA NCBI Nucleotide RefSeq
Protein NCBI Protein RefSeq
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine nbn nbn.L nbn.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards NBN OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Nbn MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Nbn Ensembl
zebrafish
ZFIN, AGR nbn ZFIN Ensembl
chicken
GEISHA NBN Ensembl
fruit fly
worm
Publications
First The cell nucleus in early bovine and caprine preimplantation embryos: fine structural cytochemistry and immunoelectron microscopy., Eur J Cell Biol 1996  
Most Recent Conservation and divergence of protein pathways in the vertebrate heart., PLoS Biol 2019                                                      
All View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 28 terms 12 terms 0 term
PANTHER nbn
KEGG Pathways K10867 K10867
KOG [K] Transcription initiation factor IIF, large subunit (RAP74)
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks nbn
Antibodies Nbn Ab1 Nbn Ab1
Clones Horizon Source BioScience Horizon Source BioScience

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