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Summary Expression Gene Literature (6) GO Terms (20) Nucleotides (386) Proteins (64) Interactants (151) Wiki
XB-GENEPAGE-943467
Gene Symbol:
kars1

Gene Name:
lysyl-tRNA synthetase 1

Synonyms:
krs , kars2 , kars ( Add synonyms , Nomenclature history )

Gene Function:
Lysyl-tRNA synthetase (class II)

Protein Function :



Interactants:
Loading ...

Diseases: 


Disease Ontology:
autosomal recessive nonsyndromic deafness [+]

OMIM:
CHARCOT-MARIE-TOOTH DISEASE, RECESSIVE INTERMEDIATE B; CMTRIB [+]

External Links:
 
Xenbase Gene ID XB-GENE-943468 XB-GENE-943473 XB-GENE-17336207
Gene Symbol kars1 kars1.L kars1.S
Chromosome Chr4 chr4L chr4S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 407964
380325
379742
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine kars1 kars1.L kars1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards KARS1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Kars MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
zebrafish
ZFIN, AGR kars1 ZFIN Ensembl
chicken
GEISHA KARS Ensembl
fruit fly
worm
Publications
First Nuclear localization of aminoacyl-tRNA synthetases using single-cell capillary electrophoresis laser-induced fluorescence analysis., Anal Chem 2004  
Most Recent Biallelic KARS pathogenic variants cause an early-onset progressive leukodystrophy., Brain 2019  
All View All Papers 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 20 terms 7 terms 7 terms
PANTHER kars1
KEGG Pathways K04567 K04567 K04567
KOG [J] Lysyl-tRNA synthetase (class II)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks kars1
ORFs kars.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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