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Summary Expression Gene Literature (4) GO Terms (19) Nucleotides (216) Proteins (33) Interactants (164) Wiki
XB-GENEPAGE-944496
Gene Symbol:
gna11

Gene Name:
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
G protein subunit Galphaq/Galphay, small G protein superfamily

Protein Function :
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Acts as an activator of phospholipase C.



Interactants:
Loading ...

Diseases: 


OMIM:
HYPOCALCEMIA, AUTOSOMAL DOMINANT 2; HYPOC2 [+]

External Links:
1/3
 
Xenbase Gene ID XB-GENE-944497 XB-GENE-17339871 XB-GENE-944503
Gene Symbol gna11 gna11.L gna11.S
Chromosome Chr01 chr1L Scaffold21
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 394755
779103
380535
mRNA RefSeq RefSeq RefSeq
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine gna11 gna11.L gna11.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards GNA11 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Gna11 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Gna11 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR gna11a gna11b ZFIN Ensembl
chicken
GEISHA GNA11 Ensembl
fruit fly
worm
Publications
First Increased expression of alphaq family G-proteins during oocyte maturation and early development of Xenopus laevis., Dev Biol 1996  
Most Recent Polycystin 1 loss of function is directly linked to an imbalance in G-protein signaling in the kidney., Development 2018                          
All View All Papers 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 16 terms 12 terms 8 terms
PANTHER gna11
KEGG Pathways K04635 K04635 K04635
KOG [T] G protein subunit Galphaq/Galphay, small G protein superfamily
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks gna11
Morpholinos gna11 MO1 , gna11 MO2 gna11 MO1 , gna11 MO2 gna11 MO1 , gna11 MO2
ORFs gna11 ORF1 , gna11 ORF2 gna11.S ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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