Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (98) GO Terms (22) Nucleotides (228) Proteins (47) Interactants (649) Wiki
Gene Symbol:

Gene Name:
replication protein A1

rp-a , hssb , rf-a , repa1 , rpa70 , mst075 , rpa ( Add synonyms , Nomenclature history )

Gene Function:
Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins

Protein Function :
As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their re...[+]

Loading ...


External Links:
Xenbase Gene ID XB-GENE-945047 XB-GENE-945055 XB-GENE-17344439
Gene Symbol rpa1 rpa1.L rpa1.S
Chromosome Chr02 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 548449
mRNA RefSeq RefSeq NCBI Nucleotide
Protein RefSeq Swiss-Prot RefSeq Swiss-Prot NCBI Protein
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine rpa1 rpa1.L rpa1.S
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
HGNC AGR, OMIM:Gene, GeneCards RPA1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
MGI, AGR Rpa1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
RGD, AGR Rpa1 Ensembl
ZFIN, AGR rpa1 ZFIN Ensembl
fruit fly
First Identification of nuclear pre-replication centers poised for DNA synthesis in Xenopus egg extracts: immunolocalization study of replication protein A., J Cell Biol 1992  
Most Recent Topoisomerase II Is Crucial for Fork Convergence during Vertebrate Replication Termination., Cell Rep 2019                  
All View All Papers 1 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 22 terms 10 terms 0 term
KEGG Pathways K07466 K07466
KOG [L] Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks rpa1
Antibodies Rpa1 Ab1 Rpa1 Ab1
ORFs rpa1 ORF2 , rpa1 ORF1 rpa1.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.14.0
Major funding for Xenbase is provided by grant P41 HD064556