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Summary Expression Gene Literature (540) GO Terms (22) Nucleotides (230) Proteins (51) Interactants (650) Wiki
XB-GENEPAGE-945046
Gene Symbol:
rpa1

Gene Name:
replication protein A1

Synonyms:
rp-a , hssb , rf-a , repa1 , rpa70 , mst075 , rpa ( Add synonyms , Nomenclature history )

Gene Function:
Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins

Protein Function :
As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their re...[+]



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-945047 XB-GENE-945055 XB-GENE-17344439
Gene Symbol rpa1 rpa1.L rpa1.S
Chromosome Chr2 chr2L chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 548449
397937
108708846
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. NCBI Protein
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine rpa1 rpa1.L rpa1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards RPA1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Rpa1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Rpa1 Ensembl
zebrafish
ZFIN, AGR rpa1 ZFIN Ensembl
chicken
GEISHA RPA1 Ensembl
fruit fly
worm
Publications
First Identification of nuclear pre-replication centers poised for DNA synthesis in Xenopus egg extracts: immunolocalization study of replication protein A., J Cell Biol 1992  
Most Recent Topoisomerase II Is Crucial for Fork Convergence during Vertebrate Replication Termination., Cell Rep 2019                  
All View All Papers 1 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 22 terms 10 terms 0 term
PANTHER rpa1
KEGG Pathways K07466 K07466
KOG [L] Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks rpa1
Antibodies Rpa1 Ab1 Rpa1 Ab1
ORFs rpa1 ORF2 , rpa1 ORF1 rpa1.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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